Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 Mice.

Autor: Rombaut, Ben^1,2 (AUTHOR) ben.rombaut@uhasselt.be, Schepers, Melissa^1,2,3 (AUTHOR) d.vandenhove@maastrichtuniversity.nl, Tiane, Assia^1,2,3 (AUTHOR) a.tiane@maastrichtuniversity.nl, Mussen, Femke^1,2,4 (AUTHOR) femke.mussen@uhasselt.be, Koole, Lisa^1,2 (AUTHOR) lisa.koole@maastrichtuniversity.nl, Kessels, Sofie¹ (AUTHOR) sofie.kessels@uhasselt.be, Trippaers, Chloë^1,5 (AUTHOR) chloe.trippaers@uhasselt.be, Jacobs, Ruben¹ (AUTHOR) ruben.jacobs@maastrichtuniversity.nl, Wouters, Kristiaan^6,7 (AUTHOR) kristiaan.wouters@maastrichtuniversity.nl, Willems, Emily^1,2 (AUTHOR) emily.willems@uhasselt.be, Veggel, Lieve van^1,2,3 (AUTHOR) lieve.vanveggel@uhasselt.be, Koulousakis, Philippos^1,2 (AUTHOR) p.koulousakis@maastrichtuniversity.nl, Deluyker, Dorien⁸ (AUTHOR) dorien.deluyker@uhasselt.be, Bito, Virginie⁸ (AUTHOR) virginie.bito@uhasselt.be, Prickaerts, Jos² (AUTHOR), Wens, Inez^1,2,3 (AUTHOR) inez.wens@uhasselt.be, Brône, Bert¹ (AUTHOR) bert.brone@uhasselt.be, van den Hove, Daniel L. A.^2,9 (AUTHOR), Vanmierlo, Tim^1,2,3 (AUTHOR) t.vanmierlo@maastrichtuniversity.nl

Publikováno v: Cells (2073-4409). Jun2024, Vol. 13 Issue 12, p1000. 21p.

Wwl70-induced ABHD6 inhibition attenuates memory deficits and pathological phenotypes in APPswe/PS1dE9 mice

Autor: Xue, Zhiwei, Ye, Lei, Ge, Jianwei, Lan, Zhen, Zou, Xinxin, Mao, Chenglu, Bao, Xinyu, Yu, Linjie, Xu, Yun, Zhu, Xiaolei

Publikováno v: In Pharmacological Research August 2023 194

Therapeutic effects of long-term HBOT on Alzheimer's disease neuropathologies and cognitive impairment in APPswe/PS1dE9 mice

Autor: Cui Yang, Guangdong Liu, Xianrong Zeng, Yang Xiang, Xi Chen, Weidong Le

Publikováno v: Redox Biology, Vol 70, Iss , Pp 103006- (2024)

Alzheimer's disease (AD) is the most common neurodegenerative disorder with the pathological hallmarks of amyloid beta (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain. Although there is a hope that anti-amyloid monoclonal antibodies may

Externí odkaz: https://doaj.org/article/cb3741da05f74216b5dc43000815d7ae

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Z-Guggulsterone attenuates cognitive defects and decreases neuroinflammation in APPswe/PS1dE9 mice through inhibiting the TLR4 signaling pathway

Autor: Liu, Jing, Lin, Ye, Yang, Yang, Guo, Yane, Shang, Yanchang, Zhou, Bo, Liu, Tianlong, Fan, Jiao, Wei, Chao

Publikováno v: In Biochemical Pharmacology August 2022 202