Zobrazeno 1 - 10
of 439
pro vyhledávání: '"APP processing"'
Autor:
Mojgan Rastegar
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Externí odkaz:
https://doaj.org/article/ed0d7cef255d4b3d93135cab1c0e5bcf
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
BackgroundPeriodontitis is one of the most common oral diseases and has been shown to be a risk factor for systemic diseases. Our aim was to investigate the relationship between periodontitis and cognitive impairment and to explore the role of the P3
Externí odkaz:
https://doaj.org/article/c5f783b8f7604670a4f242baf53e1f9c
Akademický článek
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Autor:
Maria Mensch, Jade Dunot, Sandy M. Yishan, Samuel S. Harris, Aline Blistein, Alban Avdiu, Paula A. Pousinha, Camilla Giudici, Marc Aurel Busche, Peter Jedlicka, Michael Willem, Hélène Marie
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Background Amyloid precursor protein (APP) processing is central to Alzheimer’s disease (AD) etiology. As early cognitive alterations in AD are strongly correlated to abnormal information processing due to increasing synaptic impairment, i
Externí odkaz:
https://doaj.org/article/8d3b175cccd54deba4ca41637388c576
Autor:
Yi Hu, Xu Zhang, Jing Zhang, Xinyi Xia, Huxiao Li, Che Qiu, Yue Liao, Huiwen Chen, Zhiyan He, Zhongchen Song, Wei Zhou
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Increasing evidence suggests a causal link between periodontitis and cognitive disorders. Systemic inflammation initiated by periodontitis may mediate the development of cognitive impairment. Our study aims to investigate the effe
Externí odkaz:
https://doaj.org/article/2d1c4f1cbd8f44af82a11b9ceeb6fd71
Autor:
Catarina B. Ferreira, Mikael Marttinen, Joana E. Coelho, Kaisa M.A. Paldanius, Mari Takalo, Petra Mäkinen, Luukas Leppänen, Catarina Miranda-Lourenço, João Fonseca-Gomes, Sara R. Tanqueiro, Sandra H. Vaz, Rita F. Belo, Ana Maria Sebastião, Ville Leinonen, Hilkka Soininen, Ian Pike, Annakaisa Haapasalo, Luísa V. Lopes, Alexandre de Mendonça, Maria José Diógenes, Mikko Hiltunen
Publikováno v:
Neurobiology of Disease, Vol 163, Iss , Pp 105603- (2022)
Alzheimer's disease (AD) is the most common form of dementia, which is neuropathologically characterized by extracellular senile plaques containing amyloid-β and intracellular neurofibrillary tangles composed of hyperphosphorylated tau protein. Prev
Externí odkaz:
https://doaj.org/article/64ca49ebf34d4f8fba3b77430bcc78cd
Autor:
Giulia Cencelli, Laura Pacini, Anastasia De Luca, Ilenia Messia, Antonietta Gentile, Yunhee Kang, Veronica Nobile, Elisabetta Tabolacci, Peng Jin, Maria Giulia Farace, Claudia Bagni
Publikováno v:
Cells, Vol 12, Iss 5, p 758 (2023)
Fragile X syndrome (FXS) is the most common form of monogenic intellectual disability and autism, caused by the absence of the functional fragile X messenger ribonucleoprotein 1 (FMRP). FXS features include increased and dysregulated protein synthesi
Externí odkaz:
https://doaj.org/article/bfc2cef50c6448248165690cda33d363
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Yi Hu, Huxiao Li, Jing Zhang, Xu Zhang, Xinyi Xia, Che Qiu, Yue Liao, Huiwen Chen, Zhongchen Song, Wei Zhou
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
BackgroundPeriodontitis is one of the most common oral diseases and is a potential risk factor for systemic diseases. In this study, we aimed to investigate the association between periodontitis and learning and memory impairment.MethodsWe establishe
Externí odkaz:
https://doaj.org/article/7dae9a6a51c149f394807eaab570cd9b
Autor:
Adelaide Fernandes, Cláudia Caldeira, Carolina Cunha, Elisabete Ferreiro, Ana Rita Vaz, Dora Brites
Publikováno v:
Cells, Vol 11, Iss 1, p 137 (2022)
The prevalence of Alzheimer’s disease (AD), the most common cause of age-associated dementia, is estimated to increase over the next decades. Evidence suggests neuro-immune signaling deregulation and risk genes beyond the amyloid-β (Aβ) depositio
Externí odkaz:
https://doaj.org/article/d57a4ebc31514e888496a493024594d7