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Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.

Autor: Peterson A; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Sathe A; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Zaras D; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Yang Y; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Durant A; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Deters KD; Department of Integrative Biology and Physiology, University of California, Los Angeles, California, USA., Shashikumar N; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Pechman KR; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Kim ME; Department of Computer Science, Vanderbilt University, Nashville, Tennessee, USA., Gao C; Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, Tennessee, USA., Mohd Khairi N; Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, Tennessee, USA., Li Z; Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, Tennessee, USA., Yao T; Department of Computer Science, Vanderbilt University, Nashville, Tennessee, USA., Huo Y; Department of Computer Science, Vanderbilt University, Nashville, Tennessee, USA.; Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, Tennessee, USA., Dumitrescu L; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Gifford KA; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Wilson JE; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Psychiatry and Behavioral Sciences, Center for Cognitive Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Veteran's Affairs, Geriatric Research, Education and Clinical Center, Tennessee Valley Healthcare System, Nashville, Tennessee, USA., Cambronero FE; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Risacher SL; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, Indiana, USA., Beason-Held LL; Laboratory for Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., An Y; Laboratory for Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Arfanakis K; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.; Department of Diagnostic Radiology, Rush University Medical Center, Chicago, Illinois, USA., Erus G; Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Davatzikos C; Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Tosun D; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA., Toga AW; Laboratory of Neuroimaging, USC Stevens Institute of Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Thompson PM; Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, Marina del Rey, California, USA., Mormino EC; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA., Habes M; Neuroimage Analytics Laboratory and Biggs Institute Neuroimaging Core, Glenn Biggs Institute for Neurodegenerative Disorders, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Wang D; Neuroimage Analytics Laboratory and Biggs Institute Neuroimaging Core, Glenn Biggs Institute for Neurodegenerative Disorders, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Zhang P; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Schilling K; Department of Radiology & Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Albert M; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Kukull W; National Alzheimer's Coordinating Center, University of Washington, Seattle, Washington, USA., Biber SA; National Alzheimer's Coordinating Center, University of Washington, Seattle, Washington, USA., Landman BA; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Computer Science, Vanderbilt University, Nashville, Tennessee, USA.; Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Radiology & Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA., Johnson SC; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.; Wisconsin Alzheimer's Institute, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA., Schneider J; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA., Barnes LL; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA., Jefferson AL; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Computer Science, Vanderbilt University, Nashville, Tennessee, USA., Resnick SM; Laboratory for Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Saykin AJ; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, Indiana, USA., Hohman TJ; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Archer DB; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Dec 22. Date of Electronic Publication: 2024 Dec 22.

Genetic association between the APOE ε4 allele, toxicant exposures and Gulf war illness diagnosis.

Autor: Abdullah, L^1,2 (AUTHOR) labdullah@roskampinstitute.org, Nkiliza, A² (AUTHOR), Niedospial, D¹ (AUTHOR), Aldrich, G^1,2 (AUTHOR), Bartenfelder, G¹ (AUTHOR), Keegan, A¹ (AUTHOR), Hoffmann, M¹ (AUTHOR), Mullan, M¹ (AUTHOR), Klimas, N^3,4 (AUTHOR), Baraniuk, J⁵ (AUTHOR), Crawford, F^1,2 (AUTHOR), Krengel, M⁶ (AUTHOR), Chao, L⁷ (AUTHOR), Sullivan, K⁸ (AUTHOR)

Publikováno v: Environmental Health: A Global Access Science Source. 7/6/2023, Vol. 22 Issue 1, p1-7. 7p.

Plasma NfL is associated with the APOE ε4 allele, brain imaging measurements of neurodegeneration, and lower recall memory scores in cognitively unimpaired late-middle-aged and older adults.

Autor: Malek-Ahmadi, Michael¹ (AUTHOR) michael.malekahmadi@bannerhealth.com, Su, Yi¹ (AUTHOR), Ghisays, Valentina¹ (AUTHOR), Luo, Ji¹ (AUTHOR), Devadas, Vivek¹ (AUTHOR), Chen, Yinghua¹ (AUTHOR), Lee, Wendy¹ (AUTHOR), Protas, Hillary¹ (AUTHOR), Chen, Kewei¹ (AUTHOR), Zetterberg, Henrik^2,3,4,5,6 (AUTHOR), Blennow, Kaj^2,3 (AUTHOR), Caselli, Richard J.⁷ (AUTHOR), Reiman, Eric M.^1,8,9,10 (AUTHOR)

Publikováno v: Alzheimer's Research & Therapy. 4/10/2023, Vol. 15 Issue 1, p1-10. 10p.