Zobrazeno 1 - 10
of 484
pro vyhledávání: '"APOE ε4"'
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Herpes zoster (HZ), commonly known as “shingles,” may contribute to cognitive decline through mechanisms such as neuroinflammation or direct neuronal injury. However, evidence on the longitudinal association between HZ and cog
Externí odkaz:
https://doaj.org/article/b8d2ee581ca141bf8bb96a08918d6677
Autor:
Zoe E. Neale, Jennifer R. Fonda, Mark W. Miller, Erika J. Wolf, Rui Zhang, Richard Sherva, Kelly M. Harrington, Victoria Merritt, Matthew S. Panizzon, Richard L. Hauger, J. Michael Gaziano, the VA Million Veteran Program, Mark W. Logue
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are associated with self-reported problems with cognition as well as risk for Alzheimer’s disease and related dementias (ADRD). Overlapping symptom profiles o
Externí odkaz:
https://doaj.org/article/deba554bad8742d5845318631a672ec6
Autor:
Xiaoling Wang, Xiaomin Zhang, Jing Liu, Jingjing Zhang, Congcong Liu, Yuting Cui, Qiao Song, Yuli Hou, Yaqi Wang, Qian Zhang, Yingzhen Zhang, Yujian Fan, Jianping Jia, Peichang Wang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Previous studies have demonstrated that early intervention was the best plan to inhibit the progression of Alzheimer’s disease (AD), which relied on the discovery of early diagnostic biomarkers. In this study, synaptic vesicle g
Externí odkaz:
https://doaj.org/article/416dba92365c4d508a69707518e6cb4f
Autor:
Sang-Won Han, Sang-Hwa Lee, Jong Ho Kim, Jae-Jun Lee, Young Ho Park, SangYun Kim, Kwangsik Nho, Jong-Hee Sohn
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundAlzheimer’s disease (AD) is a complex neurodegenerative disorder influenced by various factors, including liver function, which may impact the clearance of amyloid-β (Aβ) in the brain. This study aimed to explore how the apolipoprotein
Externí odkaz:
https://doaj.org/article/8a5523f08e4948efb929cc75837c39d4
Autor:
Danira Toral-Rios, Pavel Pichardo-Rojas, Elizabeth Ruiz-Sánchez, Óscar Rosas-Carrasco, Rosa Carvajal-García, Dey Carol Gálvez-Coutiño, Nancy Lucero Martínez-Rodríguez, Ana Daniela Rubio-Chávez, Myr Alcántara-Flores, Arely López-Ramírez, Alma Rosa Martínez-Rosas, Ángel Alberto Ruiz-Chow, Mario Alonso-Vanegas, Victoria Campos-Peña
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10228 (2024)
Temporal Lobe Epilepsy (TLE) is a chronic neurological disorder characterized by recurrent focal seizures originating in the temporal lobe. Despite the variety of antiseizure drugs currently available to treat TLE, about 30% of cases continue to have
Externí odkaz:
https://doaj.org/article/9b1d4d24a96148bd9ba05051ed8f7303
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionAlthough there have been many researches on the etiology and risk factors with the onset of hemifacial spasm, researches on the risk factors related to progression rate are limited. This study aims to analyze the risk factors related to t
Externí odkaz:
https://doaj.org/article/3c976d7ff0f4428ba844eb1bbcb69340
Autor:
Laura Perna, Hannah Stocker, Lena Burow, Léon Beyer, Kira Trares, Carolin Kurz, Selim Gürsel, Bernd Holleczek, Maia Tatò, Konrad Beyreuther, Ute Mons, Klaus Gerwert, Robert Perneczky, Ben Schöttker, Hermann Brenner
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background Subjective cognitive complaints (SCC) have been mostly studied in the context of Alzheimer’s disease in memory clinic settings. The potential of combining SCC with genetic information and blood biomarkers of neurodegenerative di
Externí odkaz:
https://doaj.org/article/8ca4f10d01674786a34aa01b7d7f0079
Autor:
Shaozhen Ji, Jia Kang, Chao Han, Xitong Xu, Meijie Chen, Jie Chen, Jagadish K Chhetri, Jing Pan, Piu Chan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
ObjectiveTo determine whether the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with cognitive impairment (CI) in community-dwelling Chinese older adults, and to investigate whether this relationship is modified by the
Externí odkaz:
https://doaj.org/article/3eb6ad808b01421aa417ba1a66d19ec5
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION We evaluated how the apolipoprotein E (APOE) ε4 allele modulated the spatial patterns of longitudinal atrophy in the Alzheimer's disease–vulnerable brain areas of patients with mild traumatic brain injury (mTBI) from the acut
Externí odkaz:
https://doaj.org/article/06168a36948f411681938a4019026a0e
Autor:
Andrée‐Ann Baril, Cynthia Picard, Anne Labonté, Erlan Sanchez, Catherine Duclos, Béry Mohammediyan, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, John C. S. Breitner, Sylvia Villeneuve, Judes Poirier, PREVENT‐AD Research Group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION Measuring day‐to‐day sleep variability might reveal unstable sleep‐wake cycles reflecting neurodegenerative processes. We evaluated the association between Alzheimer's disease (AD) fluid biomarkers with day‐to‐day slee
Externí odkaz:
https://doaj.org/article/f65f59e65abd48bbb9ebefd6cae1b6d9