Zobrazeno 1 - 10
of 252
pro vyhledávání: '"APLP1"'
Autor:
Sandra Schilling, Alexander August, Mathieu Meleux, Carolin Conradt, Luisa M. Tremmel, Sandra Teigler, Virginie Adam, Ulrike C. Müller, Edward H. Koo, Stefan Kins, Simone Eggert
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-24 (2023)
Abstract Background The amyloid precursor protein (APP), a key player in Alzheimer’s disease (AD), is part of a larger gene family, including the APP like proteins APLP1 and APLP2. They share similar structures, form homo- and heterotypic dimers an
Externí odkaz:
https://doaj.org/article/a809ffebfcb1404d87c26c6dbb1a7647
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Diabetic Peripheral Neuropathy (DPN) poses an escalating threat to public health, profoundly impacting well-being and quality of life. Despite its rising prevalence, the pathogenesis of DPN remains enigmatic, and existing clinical interventions fall
Externí odkaz:
https://doaj.org/article/bec6e6112bac4cd9add97e92dd1347f3
Autor:
Khue Vu Nguyen
Publikováno v:
AIMS Neuroscience, Vol 9, Iss 2, Pp 175-215 (2022)
A heterozygous Arg393His point mutation at the reactive site of antithrombin (AT) gene causing thrombosis in a Vietnamese patient is reported and named as Arg393His in AT-Hanoi. The present variant is characterized by a severe reduction of functional
Externí odkaz:
https://doaj.org/article/1f5c51639c4a4885a406cbcd8a40b05c
Autor:
Susanne Erdinger, Irmgard Amrein, Michaela Back, Susann Ludewig, Martin Korte, Jakob von Engelhardt, David P. Wolfer, Ulrike C. Müller
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The amyloid precursor protein APP plays a crucial role in Alzheimer pathogenesis. Its physiological functions, however, are only beginning to be unraveled. APP belongs to a small gene family, including besides APP the closely related amyloid precurso
Externí odkaz:
https://doaj.org/article/ffbf24cb46bb4306b854fd2685dece4f
Akademický článek
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Akademický článek
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Autor:
Phan H. Truong, Roberto Cappai, Peter J. Crouch, James B. Hilton, Giuseppe D. Ciccotosto, Catriona McLean
Publikováno v:
Cellular and Molecular Life Sciences
Motor neurone disease (MND) is a neurodegenerative disorder characterised by progressive destruction of motor neurons, muscle paralysis and death. The amyloid precursor protein (APP) is highly expressed in the central nervous system and has been show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99986fe9e64c62fa2701fc43a265697f
https://doi.org/10.1007/s00018-021-03924-5
https://doi.org/10.1007/s00018-021-03924-5
Autor:
Erdinger, Susanne, Amrein, Irmgard, Back, Michaela, Ludewig, Susann, Korte, Martin, von Engelhardt, Jakob, Wolfer, David P, Müller, Ulrike C
Publikováno v:
Frontiers in Molecular Neuroscience, 15
The amyloid precursor protein APP plays a crucial role in Alzheimer pathogenesis. Its physiological functions, however, are only beginning to be unraveled. APP belongs to a small gene family, including besides APP the closely related amyloid precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4822a96af5e15b1e09aec74ecce72fc0
https://hdl.handle.net/20.500.11850/582965
https://hdl.handle.net/20.500.11850/582965
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
François Béliveau, Christine Lavoie, Richard Leduc, Antoine Désilets, Cloé Fontaine-Carbonneau, Andréanne Laniel, Erwan Lanchec
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
The amyloid beta peptide (Aβ) is derived from the amyloid precursor protein (APP) by secretase processing. APP is also cleaved by numerous other proteases, such as the type II transmembrane serine protease matriptase, with consequences on the produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d98edca0b87f87b7ee2653b705ba04
http://link.springer.com/article/10.1038/s41598-020-67005-6
http://link.springer.com/article/10.1038/s41598-020-67005-6