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pro vyhledávání: '"APL, acute promyelocytic leukemia"'
Akademický článek
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Akademický článek
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Autor:
Haluk Demiroglu, Necla Ozer, Elifcan Aladag, Hakan Goker, Tuncay Hazirolan, Ugur Nadir Karakulak
Publikováno v:
JACC Case Reports
JACC: Case Reports, Vol 2, Iss 13, Pp 2101-2106 (2020)
JACC: Case Reports, Vol 2, Iss 13, Pp 2101-2106 (2020)
All-trans retinoic acid (ATRA) is the mainstay of treatment in patients with acute promyelocytic leukemia. Despite being effective, it can lead to cardiac complications either as a component of ATRA syndrome or an isolated form denominated as ATRA-in
Autor:
Douglas R. Almeida-Silveira, Guilherme A. dos Santos, Carolina Hassibe Thomé, Gustavo A. de Souza, Germano Aguiar Ferreira, Vitor M. Faça, Jan Jacob Schuringa, Eduardo Magalhães Rego, Diego A Pereira-Martins, Isabel Weinhäuser, Roos Houtsma
Publikováno v:
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics, 20:100091. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Molecular & Cellular Proteomics, 20:100091. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Non–T cell activation linker (NTAL) membrane protein depletion from lipid rafts by alkylphospholipids or downregulation by shRNA knockdown decreases cell viability through regulation of the Akt/PI3K pathway in mantle cell lymphoma and acute promyel
Publikováno v:
Leukemia Research Reports
Leukemia Research Reports, Vol 9, Iss, Pp 65-71 (2018)
Leukemia Research Reports, Vol 9, Iss, Pp 65-71 (2018)
Although rare, secondary clonal hematologic neoplasia may occur after successful therapy for acute promyelocytic leukemia (APL). These secondary clonal events may be considered therapy-related, but may also be due to an underlying background of clona
Autor:
David J. Milan, Jeffrey R. Winterfield
Publikováno v:
HeartRhythm Case Reports, Vol 2, Iss 4, Pp 280-282 (2016)
HeartRhythm Case Reports
HeartRhythm Case Reports
Publikováno v:
Pharmacology & Therapeutics
Herbal medicines have accumulated valuable clinical experience in thousands of years of applications in traditional Chinese medicine (TCM) or ethnomedicine. The unique multi-target efficacy on complex diseases made herbal medicines gained a global po
Autor:
Thomas G. Hofmann, Sonja Matt
Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage. Regulation of p53 activity by post-translational modifications has been linked to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d9126e8f5961f8c92c5e28c0c3e0a4
https://europepmc.org/articles/PMC6150047/
https://europepmc.org/articles/PMC6150047/
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 789-800 (2015)
FEBS Open Bio
FEBS Open Bio
Highlights • We surveyed common myeloid leukemia cell lines undergoing differentiation therapy. • Lineage progression in induced leukemia cell lines differs from nonmalignant cells. • Aberrant transcription factor expression occurs in acute mye
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 308-318 (2015)
FEBS Open Bio
FEBS Open Bio
Highlights • VAF347 augments RA-induced expression of Vav1, c-Cbl, Lyn, and P47phox. • VAF347 augments RA-induced G0/G1 enrichment. • VAF347 augments RA-induced expression of CD11b integrin receptor. • VAF347 augments RA-induced respiratory b