Zobrazeno 1 - 10
of 140
pro vyhledávání: '"APICA"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3083 (2024)
This study investigates the impact of SCs consumption by assessing the effects of three novel synthetic cannabinoids (SCs); MDMB-CHMINACA, 5F-ADB-PINACA, and APICA post-drug treatment. SCs are known for their rapid onset (
Externí odkaz:
https://doaj.org/article/acd3969f3e4c4c05a36c0edb34663b3a
Akademický článek
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Publikováno v:
Forensic Toxicology. 38:216-226
Different kinds of new synthetic cannabinoids (SCs) have been continuously developed to evade drug monitoring. Segmental hair analysis offers a longer period for retrospective drug detection compared with blood or urine. In this study, matrix-assiste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d92da1c53d11b4774ec23f887a87c36
https://doi.org/10.1007/s11419-019-00510-0
https://doi.org/10.1007/s11419-019-00510-0
Publikováno v:
Journal of Herbs, Spices & Medicinal Plants. 26:172-190
The effects of explant source, medium composition, and growth regulators were examined in callus lines of Curcuma longa. Callus cultures were induced from leaf sheath, leaf lamina, leaf base, apica...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78ebea0afa0e1f6cd28afde6ab6da8e2
https://doi.org/10.1080/10496475.2019.1689542
https://doi.org/10.1080/10496475.2019.1689542
Autor:
Rochelle Boyd, Michael Kassiou, Karen Blakey, Mitchell Longworth, Mark Connor, Tristan A. Reekie
Publikováno v:
Forensic Toxicology. 37:350-365
This work reports the synthesis and pharmacological and analytical data for a new series of recently identified azaindole-adamantyl-derived synthetic cannabinoids (SCs). Each SC was synthesised using an efficient and divergent synthesis, and assessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11cf62f598009651b9d73d18c6843f2a
https://doi.org/10.1007/s11419-019-00466-1
https://doi.org/10.1007/s11419-019-00466-1
Publikováno v:
ACS Chemical Neuroscience. 8:1673-1680
Synthetic cannabinoids (SCs) containing a 1-pentyl-1-H substituted indole or indazole are abused around the world and are associated with an array of serious side effects. These compounds undergo extensive phase 1 metabolism after ingestion with litt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fd56b3f2e3eb459e572eacbc495577
https://doi.org/10.1021/acschemneuro.7b00116
https://doi.org/10.1021/acschemneuro.7b00116
Autor:
Charles H. Mitch, Aiping Zhang, Mercedes Carpintero, Bradley Condon, C. Groshong, Shane Atwell, John W. Koss, Carl D Overshiner, Jeffrey M. Schkeryantz, Stephon C. Smith, Mark G. Bures, James E. Matt, S.R. Wasserman, Adam M. Fivush, Wesley Seidel, Carlos Jaramillo, K. Conners, David W. Bedwell, Jeffrey M. Witkin, Maria-Jesus Blanco, Daniel Ray Mayhugh, Steven James Quimby, Bruce A. Dressman, Keith A. Wafford, John T. Catlow, Allie Edward Tripp, Paul L. Ornstein, Mario Barberis, José Francisco Soriano, Steven Swanson, Beverly A. Heinz, Jon A. Erickson, Xia Li, Iain MacEwan, Thomas C. Britton, James A. Monn, Susana García-Cerrada, Jing Wang, Mark Donald Chappell, Eric George Tromiczak, Renhua Li, José Eugenio de Diego, Christine Sougias, Tatiana Natali Vetman, Xushan Wang, Stephen Antonysamy
Publikováno v:
Journal of Medicinal Chemistry. 59:10974-10993
As part of our ongoing efforts to identify novel ligands for the metabotropic glutamate 2 and 3 (mGlu2/3) receptors, we have incorporated substitution at the C3 and C4 positions of the (1S,2R,5R,6R)-2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::812f4203afd8777afc4ec3e0d87f74f0
https://doi.org/10.1021/acs.jmedchem.6b01119
https://doi.org/10.1021/acs.jmedchem.6b01119
Autor:
Ping Chen, Xiaodong Li
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience
Background: Exercise therapy has been widely applied in clinical rehabilitation as an important practical and side effect—free adjuvant therapy, with a significant effect in alleviating motor dysfunction of patients with Parkinson’s disease (PD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ecfe1955f131370ed85f9cd207f221
https://doi.org/10.3389/fnagi.2019.00255
https://doi.org/10.3389/fnagi.2019.00255
Publikováno v:
Drug Testing and Analysis. 9:378-388
N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide (APINACA) and N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide (APICA) are carboxamide-type synthetic cannabinoids comprising indazole/indole-3-carboxylic acid and adamantan-1-amine moieties. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49d52575fa7a5f0563a458d27b6142e0
https://doi.org/10.1002/dta.2124
https://doi.org/10.1002/dta.2124