Zobrazeno 1 - 10
of 70
pro vyhledávání: '"APCs, Antigen presenting cells"'
Autor:
Andrea R Delpero, Larry Karnes, Shannon E. Ronca, Shashikant Nagre, David G. Alleva, Sarah S Webb, Hanne Andersen Elyard, Allison I Jasa, Thomas M. Lancaster, JoAnn Yee, Sylaja Murikipudi, Vidhya Rao, Frans Sollie, Nishit J Shah, Freedom M Green, Melanie M Scully, Jeffrey R Haworth, Thillainaygam Sathiyaseelan, Emma K Greaves, Ramya Ragupathy, Jeffrey Klein, Todd C. Zion
Publikováno v:
Vaccine
AKS-452 is a biologically-engineered vaccine comprising an Fc fusion protein of the SARS-CoV-2 viral spike protein receptor binding domain antigen (Ag) and human IgG1 Fc (SP/RBD-Fc) in clinical development for the induction and augmentation of neutra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbd52d976e8f0e684d66cd171ccbc43
https://doi.org/10.1016/j.vaccine.2021.09.077
https://doi.org/10.1016/j.vaccine.2021.09.077
Publikováno v:
Neoplasia (New York, N.Y.)
Early lung carcinoma development may be modulated by innate host cellular mechanisms that promote tumor growth and invasion. We recently identified how a loss-of-function mutation in the glycan sulfating enzyme N-deacetylase/N-sulfotransferase-1 (Nds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c1a8c4e83557920ae120f81f6685b95
http://europepmc.org/articles/PMC8560828
http://europepmc.org/articles/PMC8560828
Autor:
Yihui Yang, Xiangjin Zheng, Sha Li, Jinyi Liu, Wan Li, Jie Yi, Weiqi Fu, Jinhua Wang, Guanhua Du, Liwen Ren
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2783-2797 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon fusion of multivesicular bodies with the cell surface. They can transport nucleic acids, proteins, and lipids for intercellular communication and activate signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfeee0d62636797c4da5264a84ca925
https://doi.org/10.1016/j.apsb.2021.01.001
https://doi.org/10.1016/j.apsb.2021.01.001
Autor:
Philip Manning, S. Moein Moghimi, Wing Man Lau, Eldhose Skaria, Keng Wooi Ng, Rachael V. Dixon, Mark A. Birch-Machin
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2344-2361 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Recent infectious disease outbreaks, such as COVID-19 and Ebola, have highlighted the need for rapid and accurate diagnosis to initiate treatment and curb transmission. Successful diagnostic strategies critically depend on the efficiency of biologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b221e8e2687471aecd4df6fbd917e9a7
http://www.sciencedirect.com/science/article/pii/S2211383521000484
http://www.sciencedirect.com/science/article/pii/S2211383521000484
Publikováno v:
Bioactive Materials
Bioactive Materials, Vol 6, Iss 7, Pp 1973-1987 (2021)
Bioactive Materials, Vol 6, Iss 7, Pp 1973-1987 (2021)
The tumor development and metastasis are closely related to the structure and function of the tumor microenvironment (TME). Recently, TME modulation strategies have attracted much attention in cancer immunotherapy. Despite the preliminary success of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9e3a12774af1e45fb188f205ad9bdc
https://doi.org/10.1016/j.bioactmat.2020.12.010
https://doi.org/10.1016/j.bioactmat.2020.12.010
Autor:
Zhonggui He, Yixin Sun, Gang Wang, Linlin Cao, Yang Wang, Qikun Jiang, Jin Sun, Dongyang Zhao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1382-1396 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Hypoxia, a salient feature of most solid tumors, confers invasiveness and resistance to the tumor cells. Oxygen-consumption photodynamic therapy (PDT) suffers from the undesirable impediment of local hypoxia in tumors. Moreover, PDT could further wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55dbc5e9669afc312da6e54f6cee2e96
https://doi.org/10.1016/j.apsb.2020.01.004
https://doi.org/10.1016/j.apsb.2020.01.004
Autor:
Christine M. Akamine, Hana M. El Sahly
Publikováno v:
Translational Research
The mRNA therapeutics have been studied since the 1970s and the currently available mRNA vaccines against COVID-19 are the culmination of decades of scientific research. The mRNA vaccines BNT162b2 and mRNA-1273 have played a key role in our global re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5fb17a5ba87457527cd1ba281170c15
https://pubmed.ncbi.nlm.nih.gov/34954088
https://pubmed.ncbi.nlm.nih.gov/34954088
Autor:
Hae Li Ko, Kyung Won Kang, Manki Song, Sang-Myeong Lee, Hye-Lim Park, Jae-Ouk Kim, Hye-Jung Kim, Jae-Hwan Nam, Eui-Cheol Shin, Hye Won Kwak, Seung Rok Ryu, Hyo Jung Park, Dae Gwin Jeong, Rhoon-Ho Kim, Min Ho Cha, Hun Kim
Publikováno v:
Vaccine
Highlights • RNA adjuvant was developed from the CrPV intergenic region IRES. • The RNA adjuvant functioned as an adjuvant with protein-based vaccines. • The RNA adjuvant increased vaccine efficacy and induced balanced Th1/Th2 response. • The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bee6776ec07d79debcbc88725f48c1
https://doi.org/10.1016/j.vaccine.2019.07.070
https://doi.org/10.1016/j.vaccine.2019.07.070
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 4, Pp 675-689 (2019)
Acta Pharmaceutica Sinica B, Vol 9, Iss 4, Pp 675-689 (2019)
Erythrocytes (red blood cells, RBCs) are the most abundant circulating cells in the blood and have been widely used in drug delivery systems (DDS) because of their features of biocompatibility, biodegradability, and long circulating half-life. Accord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0114f126bb7f05846b43a30dd847397c
http://europepmc.org/articles/PMC6663920
http://europepmc.org/articles/PMC6663920
Autor:
Karl R. Clauser, Steven A. Carr, Daniel B. Graham, Shira Weingarten-Gabbay, Susan Klaeger, Jennifer G. Abelin, Hannah B. Taylor, Siranush Sarkizova
Publikováno v:
Molecular & Cellular Proteomics : MCP
Immunotherapies have emerged to treat diseases by selectively modulating a patient’s immune response. Although the roles of T and B cells in adaptive immunity have been well studied, it remains difficult to select targets for immunotherapeutic stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d3c27b5c73a09d43bed1593d25ed23
http://europepmc.org/articles/PMC8327157
http://europepmc.org/articles/PMC8327157