Zobrazeno 1 - 10
of 176
pro vyhledávání: '"APARNA, D."'
Autor:
Lorey K. Smith, Tiffany Parmenter, Margarete Kleinschmidt, Eric P. Kusnadi, Jian Kang, Claire A. Martin, Peter Lau, Riyaben Patel, Julie Lorent, David Papadopoli, Anna Trigos, Teresa Ward, Aparna D. Rao, Emily J. Lelliott, Karen E. Sheppard, David Goode, Rodney J. Hicks, Tony Tiganis, Kaylene J. Simpson, Ola Larsson, Benjamin Blythe, Carleen Cullinane, Vihandha O. Wickramasinghe, Richard B. Pearson, Grant A. McArthur
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Different adaptive mechanisms have been reported to reduce the efficacy of mutant BRAF inhibition in melanoma. Here, the authors show BRAF inhibition induces the translational regulation of metabolic genes leading to acquired therapy resistance.
Externí odkaz:
https://doaj.org/article/059612c027f74f17b5f4fdc038786683
Autor:
AbuHammad, Shatha, Cullinane, Carleen, Martin, Claire, Bacolas, Zoe, Ward, Teresa, Chen, Huiqin, Slater, Alison, Ardley, Kerry, Kirby, Laura, Chan, Keefe T., Brajanovski, Natalie, Smith, Lorey K., Rao, Aparna D., Lelliott, Emily J., Kleinschmidt, Margarete, Vergara, Ismael A., Papenfuss, Anthony T., Lau, Peter, Ghosh, Prerana, Haupt, Sue, Haupt, Ygal, Sanij, Elaine, Poortinga, Gretchen, Pearson, Richard B., Falk, Hendrik, Curtis, David J., Stupple, Paul, Devlin, Mark, Street, Ian, Davies, Michael A., McArthur, Grant A., Sheppard, Karen E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Apr . 117(17), 9644-9645.
Externí odkaz:
https://www.jstor.org/stable/26929974
Autor:
AbuHammad, Shatha, Cullinane, Carleen, Martin, Claire, Bacolas, Zoe, Ward, Teresa, Chen, Huiqin, Slater, Alison, Ardley, Kerry, Kirby, Laura, Chan, Keefe T., Brajanovski, Natalie, Smith, Lorey K., Rao, Aparna D., Lelliott, Emily J., Kleinschmidt, Margarete, Vergara, Ismael A., Papenfuss, Anthony T., Lau, Peter, Ghosh, Prerana, Haupt, Sue, Haupt, Ygal, Sanij, Elaine, Poortinga, Gretchen, Pearson, Richard B., Falk, Hendrik, Curtis, David J., Stupple, Paul, Devlin, Mark, Street, Ian, Davies, Michael A., McArthur, Grant A., Sheppard, Karen E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Sep 01. 116(36), 17990-18000.
Externí odkaz:
https://www.jstor.org/stable/26851238
Autor:
Deepak N Singh, Kumar Chandan Srivastava, Aparna D Potsangbam, Deepti Shrivastava, Doddabasavaiah Basavapur Nandini, Wahengbam T Singh, Koijam S Singh
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 12, Iss 5, Pp 324-331 (2020)
Background and Objective: The role of inducible nitric oxide synthase (iNOS) has been implicated in various pathological processes including oral carcinoma. Oral premalignancy being its precursor lesion is also expected to show similar pattern. This
Externí odkaz:
https://doaj.org/article/5b4bb9e943d24272a4512b2aeee0b14a
Publikováno v:
Journal of Wound Care. 32:lxiii-lxxiv
Objective: Treatment of contaminated wounds represents a significant challenge in healthcare and there is a need to develop approaches maximising skin retention to maintain therapeutic concentrations of anti-infectives at the wound site. The objectiv
Autor:
Nicholas C. Allen, Andrew J. Martin, Victoria A. Snaidr, Renee Eggins, Alvin H. Chong, Pablo Fernandéz-Peñas, Douglas Gin, Shireen Sidhu, Vanessa L. Paddon, Leith A. Banney, Adrian Lim, Edward Upjohn, Helmut Schaider, Aparna D. Ganhewa, Jennifer Nguyen, Catriona A. McKenzie, Saurabh Prakash, Catriona McLean, Alistair Lochhead, Jan Ibbetson, Andrew Dettrick, Anthony Landgren, Katherine J. Allnutt, Clare Allison, Rachael B. Davenport, Blake P. Mumford, Brittany Wong, Brendan Stagg, Alexander Tedman, Hannah Gribbin, Harrison A. Edwards, Nicholas De Rosa, Thomas Stewart, Brent J. Doolan, Yonatan Kok, Kate Simpson, Zhi M. Low, Tom Kovitwanichkanont, Richard A. Scolyer, Haryana M. Dhillon, Janette L. Vardy, Steven J. Chadban, David G. Bowen, Andrew C. Chen, Diona L. Damian
Publikováno v:
New England Journal of Medicine. 388:804-812
Publikováno v:
Holland‐Frei Cancer Medicine. :1-14
Publikováno v:
In Pharmacological Research May 2016 107:42-47
Publikováno v:
Current Drug Therapy. 18
Abstract: COVID-19 was deemed a global pandemic by the World Health Organization in February 2020. The prevalence of viral diseases worldwide has increased the importance of receiving immediate medical attention. There is currently no specific medica
Autor:
Akash K. Kaushik, Amy Tarangelo, Lindsey K. Boroughs, Mukundan Ragavan, Yuanyuan Zhang, Cheng-Yang Wu, Xiangyi Li, Kristen Ahumada, Jui-Chung Chiang, Vanina T. Tcheuyap, Faeze Saatchi, Quyen N. Do, Cissy Yong, Tracy Rosales, Christina Stevens, Aparna D. Rao, Brandon Faubert, Panayotis Pachnis, Lauren G. Zacharias, Hieu Vu, Feng Cai, Thomas P. Mathews, Giannicola Genovese, Barbara S. Slusher, Payal Kapur, Xiankai Sun, Matthew Merritt, James Brugarolas, Ralph J. DeBerardinis
Publikováno v:
Science advances. 8(50)
Targeting metabolic vulnerabilities has been proposed as a therapeutic strategy in renal cell carcinoma (RCC). Here, we analyzed the metabolism of patient-derived xenografts (tumorgrafts) from diverse subtypes of RCC. Tumorgrafts from VHL -mutant cle