Zobrazeno 1 - 10
of 17
pro vyhledávání: '"AP, area postrema"'
Autor:
Henriette Frikke-Schmidt, Randy J. Seeley, Joseph W. Galaske, Martin G. Myers, Karin Hultman, Sebastian Beck Jørgensen
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 21, Iss, Pp 13-21 (2019)
Molecular Metabolism, Vol 21, Iss, Pp 13-21 (2019)
Objective Analogues of GDF15 (Growth Differentiation Factor 15) are promising new anti-obesity therapies as pharmacological treatment with GDF15 results in dramatic reductions of food intake and body weight. GDF15 exerts its central anorexic effects
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 5, Iss 10, Pp 834-843 (2016)
Molecular Metabolism, Vol 5, Iss 10, Pp 834-843 (2016)
Objective Adult neurogenesis in the subgranular zone and subventricular zone is generally accepted, but its existence in other brain areas is still controversial. Circumventricular organs, such as the area postrema (AP) have recently been described a
Autor:
Emmanuel Gilissen, Tanya Calvey, Paul R. Manger, John D. Pettigrew, Consolate Kaswera-Kyamakya, Nina Patzke, Mads F. Bertelsen
Publikováno v:
Journal of Chemical Neuroanatomy
Highlights • Cholinergic, catecholaminergic, serotonergic and orexinergic systems in the brains of strepsirrhine primates are described. • All species show a similar global pattern of nuclear organization of these systems. • For these systems t
Autor:
Cork, Simon C, Richards, James E, Holt, Marie K, Gribble, Fiona M, Reimann, Frank, Trapp, Stefan
Publikováno v:
Molecular Metabolism, Vol 4, Iss 10, Pp 718-731 (2015)
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable. This study investiga
Publikováno v:
Temperature: Multidisciplinary Biomedical Journal
Diverse transmitter systems (e.g. acetylcholine, dopamine, endocannabinoids, endorphins, glutamate, histamine, 5-hydroxytryptamine, substance P) have been implicated in the pathways by which nausea and vomiting are induced and are targets for anti-em
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 11, Pp 1350-1359 (2017)
Molecular Metabolism, Vol 6, Iss 11, Pp 1350-1359 (2017)
Objective Glucagon-like peptides are co-released from enteroendocrine L cells in the gut and preproglucagon (PPG) neurons in the brainstem. PPG-derived GLP-1/2 are probably key neuroendocrine signals for the control of energy balance and glucose home
Autor:
Angela M. Ramos-Lobo, Daniella do Carmo Buonfiglio, Carol F. Elias, Lais I. Cardinali, João A.B. Pedroso, Isadora C. Furigo, Jose Donato, Julio Tirapegui
Publikováno v:
Molecular Metabolism
Therapies that improve leptin sensitivity have potential as an alternative treatment approach against obesity and related comorbidities. We investigated the effects of Socs3 gene ablation in different mouse models to understand the role of SOCS3 in t
Autor:
Simon C, Cork, James E, Richards, Marie K, Holt, Fiona M, Gribble, Frank, Reimann, Stefan, Trapp
Publikováno v:
Molecular Metabolism
Objective Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable. This study investigated the novel GLP-1R-
Autor:
A. de Vries, Graham A. W. Rook, Andrea Evans, Jacob Harvey Hollis, Jon R. F. Hunt, Julian F. R. Paton, E. van Kampen, B. Pan, Christopher A. Lowry, Stafford L. Lightman, DM Knight, Laura Rosa Brunet
Publikováno v:
Neuroscience
Peripheral immune activation can have profound physiological and behavioral effects including induction of fever and sickness behavior. One mechanism through which immune activation or immunomodulation may affect physiology and behavior is via action
Publikováno v:
Neuroscience
Highlights • Spinal GLP-1 axons target primarily sympathetic preganglionic neurons. • Spinal GLP-1 axons innervate interneurons that may regulate sympathetic outflow. • Many GLP-1 neurons in the medulla are spinally-projecting. • The lumbar c