Zobrazeno 1 - 10
of 18
pro vyhledávání: '"ANWAR SHEED KHAN"'
Autor:
Sajjad Ahmad, Jawad Ahmed, Eman H. Khalifa, Farhad Ali Khattak, Anwar Sheed khan, Syed Umar Farooq, Sannaa M.A. Osman, Magdi M. Salih, Nadeem Ullah, Taj Ali Khan
Publikováno v:
Journal of Infection and Public Health, Vol 16, Iss 9, Pp 1368-1378 (2023)
Background: The IL-12/23/ISG15-IFN-γ pathway is the main immunological pathway for controlling intra-macrophagic microorganisms such as Mycobacteria, Salmonella, and Leishmania spp. Consequently, upon mutations in genes of the IL-12/23/ISG15-IFN-γ
Externí odkaz:
https://doaj.org/article/2cf49dd5f260447a8015562e9a94e718
Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan
Autor:
Gary Napier, Anwar Sheed Khan, Abdul Jabbar, Muhammad Tahir Khan, Sajid Ali, Muhammad Qasim, Noor Mohammad, Rumina Hasan, Zahra Hasan, Susana Campino, Sajjad Ahmad, Baharullah Khattak, Simon J. Waddell, Taj Ali Khan, Jody E. Phelan, Taane G. Clark
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Tuberculosis, caused by Mycobacterium tuberculosis, is a high-burden disease in Pakistan, with multi-drug (MDR) and extensive-drug (XDR) resistance, complicating infection control. Whole genome sequencing (WGS) of M. tuberculosis is being us
Externí odkaz:
https://doaj.org/article/e9e9a17025eb4d2199855338fa7f1d4e
Autor:
Anwar Sheed Khan, Jody E. Phelan, Muhammad Tahir Khan, Sajid Ali, Muhammad Qasim, Gary Napier, Susana Campino, Sajjad Ahmad, Otavio Marques Cabral, Shulin Zhang, Hazir Rahman, Dong-Qing Wei, Taane G. Clark, Taj Ali Khan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis, is endemic in Pakistan. Resistance to both firstline rifampicin and isoniazid drugs (multidrug-resistant TB; MDR-TB) is hampering disease control. Rifampicin resistance is attributed t
Externí odkaz:
https://doaj.org/article/641c2d4cd264462fbb84db67d61c18c5
Autor:
Muhammad Tahir Khan, Sajid Ali, Anwar Sheed Khan, Noor Muhammad, Faiza Khalil, Muhammad Ishfaq, Muhammad Irfan, Abdullah G. Al-Sehemi, Shabbir Muhammad, Arif Malik, Taj Ali Khan, Dong Qing Wei
Publikováno v:
ACS Omega, Vol 6, Iss 10, Pp 6588-6599 (2021)
Externí odkaz:
https://doaj.org/article/89c19e0965b64ab6b151644bd1ddac3e
Autor:
Muhammad Tahir khan, Shaukat Iqbal Malik, Sajid Ali, Nayyer Masood, Tariq Nadeem, Anwar Sheed Khan, Muhammad Tanvir Afzal
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Pyrazinamide (PZA) is an important component of first-line drugs because of its distinctive capability to kill subpopulations of persistent Mycobacterium tuberculosis (MTB). The prodrug (PZA) is converted to its active form, pyraz
Externí odkaz:
https://doaj.org/article/8746672e891741a3b5564a870f7a230d
Publikováno v:
Journal of the Pakistan Medical Association, Vol 71, Iss 3 (2021)
Abstract Objective: To explore the burden of drug resistant tuberculosis in Khyber Pakhtunkhwa, Pakistan. Methods: A total of 8220 referred suspected TB patient samples were collected from 1st March 2016 to 28th February 2017 from TB laboratories
Externí odkaz:
https://doaj.org/article/20d5d004d4d341a3828f46537beb262f
Autor:
SAJID ALI, MUHAMMAD TAHIR KHAN, ANWAR SHEED KHAN, NOOR MOHAMMAD, MUHAMMAD MUMTAZ KHAN, SAJJAD AHMAD, SADIQ NOOR, ABDUL JABBAR, CANTILLON DAIRE, FARIHA HASSAN
Publikováno v:
Polish Journal of Microbiology, Vol 69, Iss i_current (2020)
Externí odkaz:
https://doaj.org/article/f971f3a0511d4d62847877c2f337a414
Autor:
Aamir Mehmood, Muhammad Tahir Khan, Aman Chandra Kaushik, Anwar Sheed Khan, Muhammad Irfan, Dong-Qing Wei
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Pyrazinamide (PZA) is one of the main FDA approved drugs to be used as the first line of defense against Mycobacterium Tuberculosis (MTB). It is activated into pyrazinoic acid (POA) via MTB's pncA gene-encoded pyrazinamidase (PZase). Mutations are mo
Externí odkaz:
https://doaj.org/article/a8fcae9137fc44f5958f9cce2c096628
Autor:
Anwar Sheed Khan, Jody E. Phelan, Muhammad Tahir Khan, Sajid Ali, Muhammad Qasim, Gary Napier, Susana Campino, Sajjad Ahmad, Otavio Cabral-Marques, Shulin Zhang, Hazir Rahman, Dong-Qing Wei, Taane G. Clark, Taj Ali Khan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/e0f8cf1232424098a5334ea195a843ec
Autor:
Anwar Sheed Khan, Jody E. Phelan, Muhammad Tahir Khan, Sajid Ali, Muhammad Qasim, Noor Mohammad, Gary Napier, Sajjad Ahmad, Jamshed Alam, Baharullah Khattak, Susana Campino, Taane G. Clark, Taj Ali Khan
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 138
Tuberculosis, caused by Mycobacterium tuberculosis, is a major public health issue in Pakistan. Isoniazid is a first-line pro-drug that requires activation through an enzyme called catalase peroxidase, but is subject to widespread resistance, driven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5433a0a52f4b1b930ca91aba6e960f9
https://pubmed.ncbi.nlm.nih.gov/36463715
https://pubmed.ncbi.nlm.nih.gov/36463715