Zobrazeno 1 - 10
of 165
pro vyhledávání: '"ANTONIO GIUSEPPE NACCARATO"'
Autor:
Stefania Crucitta, Francesco Pasqualetti, Alessandra Gonnelli, Martina Ruglioni, Giovanna Irene Luculli, Martina Cantarella, Valerio Ortenzi, Cristian Scatena, Fabiola Paiar, Antonio Giuseppe Naccarato, Romano Danesi, Marzia Del Re
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Circulating cell-free DNA (cfDNA, liquid biopsy) is a powerful tool to detect molecular alterations. However, depending on tumor characteristics, biology and anatomic localization, cfDNA detection and analysis may be challenging.
Externí odkaz:
https://doaj.org/article/8711305b7cb2476693f032c8b3a5f8d5
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/84f8db96b58247d3aff5eaa39dcb9f07
Autor:
Mariangela Morelli, Francesca Lessi, Serena Barachini, Romano Liotti, Nicola Montemurro, Paolo Perrini, Orazio Santo Santonocito, Carlo Gambacciani, Matija Snuderl, Francesco Pieri, Filippo Aquila, Azzurra Farnesi, Antonio Giuseppe Naccarato, Paolo Viacava, Francesco Cardarelli, Gianmarco Ferri, Paul Mulholland, Diego Ottaviani, Fabiola Paiar, Gaetano Liberti, Francesco Pasqualetti, Michele Menicagli, Paolo Aretini, Giovanni Signore, Sara Franceschi, Chiara Maria Mazzanti
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundGlioblastoma (GB) is the most severe form of brain cancer, with a 12-15 month median survival. Surgical resection, temozolomide (TMZ) treatment, and radiotherapy remain the primary therapeutic options for GB, and no new therapies have been
Externí odkaz:
https://doaj.org/article/a0c643cddb5e4ccf92ca9ca6b88b0ff3
New insights in the expression of stromal caveolin 1 in breast cancer spread to axillary lymph nodes
Autor:
Cristian Scatena, Giovanni Fanelli, Giuseppe Nicolò Fanelli, Michele Menicagli, Paolo Aretini, Valerio Ortenzi, Sara Piera Civitelli, Lorenzo Innocenti, Federica Sotgia, Michael P. Lisanti, Antonio Giuseppe Naccarato
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Recent evidence suggests that a loss of expression of caveolin in the stromal compartment (sCav-1) of human invasive breast carcinoma (IBC) may be a predictor of disease recurrence, metastasis and poor outcome. At present, there is little kn
Externí odkaz:
https://doaj.org/article/daa8355ce42840c988783df105fba6a4
Autor:
Cristian Scatena, Sara Franceschi, Maria Franzini, Chiara Sanguinetti, Nadia Romiti, Laura Caponi, Mario Mandalà, Chiara Maria Mazzanti, Antonio Giuseppe Naccarato
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Neoplastic cells promote a hypercoagulable state by the expression of cell surface proteins, such as tissue factor. In BRAFv600 mutated melanoma patients upon BRAF inhibitors, a hypercoagulable state correlates with prognosis, whi
Externí odkaz:
https://doaj.org/article/cb3e35aeda904db5b9f43d41ed771174
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The processes of recurrence and metastasis, through which cancer relapses locally or spreads to distant sites in the body, accounts for more than 90% of cancer-related deaths. At present there are very few treatment options for patients at this stage
Externí odkaz:
https://doaj.org/article/54445c1b5de4490ab194b451a7453d5d
Autor:
Prospero Civita, Sara Franceschi, Paolo Aretini, Valerio Ortenzi, Michele Menicagli, Francesca Lessi, Francesco Pasqualetti, Antonio Giuseppe Naccarato, Chiara Maria Mazzanti
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Laser capture microdissection (LCM) coupled with RNA-seq is a powerful tool to identify genes that are differentially expressed in specific histological tumor subtypes. To better understand the role of single tumor cell populations in the complex het
Externí odkaz:
https://doaj.org/article/4dee5e5eaf434870a049ce0045876c10
Autor:
Alessandro Apollo, Valerio Ortenzi, Cristian Scatena, Katia Zavaglia, Paolo Aretini, Francesca Lessi, Sara Franceschi, Sara Tomei, Carlo Alberto Sepich, Paolo Viacava, Chiara Maria Mazzanti, Antonio Giuseppe Naccarato
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210635 (2019)
BackgroundBladder cancer (BC) is the 9th most common cancer diagnosis worldwide. Low grade (LG) represents 70% of all BCs, characterized by recurrence and rare ability (10-15%) to progress to high grade (HG) and invade. The remaining 30% is high grad
Externí odkaz:
https://doaj.org/article/203481e447544f468e2d74d702ddb16c
Autor:
Cristian Scatena, Manuela Roncella, Antonello Di Paolo, Paolo Aretini, Michele Menicagli, Giovanni Fanelli, Carolina Marini, Chiara Maria Mazzanti, Matteo Ghilli, Federica Sotgia, Michael P. Lisanti, Antonio Giuseppe Naccarato
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Background and objectives: Cancer stem cells (CSCs) have been implicated in tumor initiation, recurrence, metastatic spread and poor survival in multiple tumor types, breast cancers included. CSCs selectively overexpress key mitochondrial-related pro
Externí odkaz:
https://doaj.org/article/e6c0448c52944cf6ba869f3cd03e3fd6
Autor:
Luisa Maresca, Samuele Lodovichi, Alessandra Lorenzoni, Tiziana Cervelli, Rossella Monaco, Laura Spugnesi, Mariella Tancredi, Elisabetta Falaschi, Katia Zavaglia, Elisabetta Landucci, Manuela Roncella, Caterina Congregati, Angiolo Gadducci, Antonio Giuseppe Naccarato, Maria Adelaide Caligo, Alvaro Galli
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
In this study, we determined if BRCA1 partners involved in DNA double-strand break (DSB) and mismatch repair (MMR) may contribute to breast and ovarian cancer development. Taking advantage the functional conservation of DNA repair pathways between ye
Externí odkaz:
https://doaj.org/article/e639c8c962944410837a5ab480c63c8e