Zobrazeno 1 - 10
of 4 968
pro vyhledávání: '"ANTIVIRAL DRUGS"'
Autor:
Jixiang Liang, Weihang Xu, Xiaoming Pan, Shiyun Han, Linwei Zhang, Hao Wen, Mingyue Ding, Wanpo Zhang, Dapeng Peng
Publikováno v:
Veterinary Quarterly, Vol 44, Iss 1, Pp 1-49 (2024)
The porcine enteric coronaviruses (PECs) currently reported include porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), and swine acute diarrhea syndrome coronavirus (SADS-CoV). In the
Externí odkaz:
https://doaj.org/article/90daa24fcbf54185a3f390550f07686b
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 11, Pp 12847-12865 (2024)
The pathogen of COVID-19, SARS-CoV-2, has caused a severe global health crisis. So far, while COVID-19 has been suppressed, the continuous evolution of SARS-CoV-2 variants has reduced the effectiveness of vaccines such as mRNA-1273 and drugs such as
Externí odkaz:
https://doaj.org/article/1a7b487bed5343758b5ab6789f7ede0e
Autor:
Patrik Roser, Mona Brunstein, Michael Specka, Jörg Timm, Stefan Kühnhold, Fabrizio Schifano, Udo Bonnet, Norbert Scherbaum
Publikováno v:
Harm Reduction Journal, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background Direct acting antivirals (DAAs) as a curative treatment of hepatitis C have been available for several years and have replaced interferon-containing therapies. However, treatment rates of people who inject drugs (PWID) are declini
Externí odkaz:
https://doaj.org/article/9861bcb80e984246810b3ef275bf47ed
Publikováno v:
Virus Research, Vol 350, Iss , Pp 199503- (2024)
Equine infectious anemia virus (EIAV) is an equine lentivirus related to human immunodeficiency virus type 1 (HIV-1). Both viruses are related among the Retroviridae family, but their clinical manifestations are different as EIAV causes a long persis
Externí odkaz:
https://doaj.org/article/41a27a0fec034d4c881ade9df17431df
Autor:
Yulong Wang, Linjin Fan, Pengfei Ye, Zequn Wang, Chudan Liang, Quan Liu, Xiaofeng Yang, Zhenyu Long, Wendi Shi, Yuandong Zhou, Jingyan Lin, Huijun Yan, Hongxin Huang, Linna Liu, Jun Qian
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Nipah virus (NiV), a highly pathogenic Henipavirus in humans, has been responsible for annual outbreaks in recent years. Experiments involving live NiV are highly restricted to biosafety level 4 (BSL-4) laboratories, which impedes NiV research. In th
Externí odkaz:
https://doaj.org/article/1fcd8756fc974de7a5f6d51976888bd1
Autor:
Elodie Bomfim Hyppolito, Alberto Novaes Ramos Jr, Larissa Peixoto Teixeira, Arthur Machado Bezerra, Lucas Arruda Mendes, Taynara Lais Silva, José Milton de Castro Lima, Érico Antonio Gomes de Arruda, Eder Janes Guerra, Maria Macedo Saraiva Tavares, Carlos Eduardo Pereira Lima, Ticiana Mota Esmeraldo, Francisco Sérgio Rangel de Paula Pessoa, Alessandra Maria Montalverne Pierre, Karla Brandão Pereira, Antônio Haroldo Araújo Filho, Lívia Melo Carone Linhares, Anderson Fuentes Ferreira, Roberto da Justa Pires Neto
Publikováno v:
Revista da Sociedade Brasileira de Medicina Tropical, Vol 57 (2024)
ABSTRACT Background: This study aimed to evaluate the effectiveness and safety of direct-acting antivirals (DAAs) for hepatitis C treatment by measuring sustained virologic response (SVR) and serious adverse events to help design effective interventi
Externí odkaz:
https://doaj.org/article/6c0837740663476eb1bc38e67ab0a66f
Autor:
M. A. Zakharova, M. V. Chudinov
Publikováno v:
Тонкие химические технологии, Vol 19, Iss 3, Pp 214-231 (2024)
Objectives. To describe the pharmaceutical technology of controlled degradation of protein molecules (PROTAC®, Proteolysis Targeting Chimera), approaches to the design of the PROTAC® molecule, methods of ligand and linker selection and synthesis, a
Externí odkaz:
https://doaj.org/article/ada0adb00df44d4e8dbe708ae2f25183
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-16 (2024)
Abstract Coronaviruses employ various strategies for survival, among which the activation of endogenous or exogenous apoptosis stands out, with viral proteins playing a pivotal role. Notably, highly pathogenic coronaviruses such as SARS-CoV-2, SARS-C
Externí odkaz:
https://doaj.org/article/8901bba9bc52497b98943b8fd769d2a0
Autor:
M. N. Dunaeva
Publikováno v:
Антибиотики и Химиотерапия, Vol 69, Iss 3-4, Pp 73-94 (2024)
Influenza is an acute respiratory viral infection, known for its epidemics and pandemics, claiming millions of lives everywhere. Influenza A virus (Orthomyxoviridae family), whose genome consists of 8 RNA segments of negative polarity, is widespread
Externí odkaz:
https://doaj.org/article/ea4065bc73a246aebc23d090e04f4c8c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The ongoing COVID-19 pandemic continues to pose significant challenges worldwide, despite widespread vaccination. Researchers are actively exploring antiviral treatments to assess their efficacy against emerging virus variants. The aim of th
Externí odkaz:
https://doaj.org/article/d784abca3ed04706996c1700472719bb