Výsledky vyhledávání - "ANTIAPOPTOTIC PROTEINS"

Akademický článek

Molecular docking study of naturally derived flavonoids with antiapoptotic BCL-2 and BCL-XL proteins toward ovarian cancer treatment

Autor: Mohd Faiz Abd Ghani, Rozana Othman, Noraziah Nordin

Publikováno v: Journal of Pharmacy and Bioallied Sciences, Vol 12, Iss 6, Pp 676-680 (2020)

The naturally derived flavonoids are well known to have anticarcinogenic effects. Flavonoids could be an alternative strategy for ovarian cancer treatment, due to existing platinum-based drugs are reported to develop resistance with low survival rate

Externí odkaz: https://doaj.org/article/0840bff13a35468fa026b08055167ccd

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Akademický článek

Plant Signalling Components EDS1 and SGT1 Enhance Disease Caused by the Necrotrophic Pathogen Botrytis cinerea

Autor: Bouarab, Kamal

Publikováno v: The New Phytologist, 2007 Jan 01. 175(1), 131-139.

Externí odkaz: https://www.jstor.org/stable/4641030

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Molecular Docking Study of Naturally Derived Flavonoids with Antiapoptotic BCL-2 and BCL-XL Proteins toward Ovarian Cancer Treatment

Autor: Rozana Othman, Mohd Faiz Abd Ghani, Noraziah Nordin

Publikováno v: Journal of Pharmacy & Bioallied Sciences
Journal of Pharmacy and Bioallied Sciences, Vol 12, Iss 6, Pp 676-680 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6d9b718900aef04d63d49b944d4856
http://europepmc.org/articles/PMC8021047

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c-FLIP, a Novel Biomarker for Cancer Prognosis, Immunosuppression, Alzheimer's Disease, Chronic Obstructive Pulmonary Disease (COPD), and a Rationale Therapeutic Target

Autor: Khadijeh Bijangi-Vishehsaraei, Ahmad R. Safa, Krzysztof Kamocki, M. Reza Saadatzadeh

Publikováno v: Biomarkers journal

Dysregulation of c-FLIP (cellular FADD-like IL-1β-converting enzyme inhibitory protein) has been shown in several diseases including cancer, Alzheimer’s disease, and chronic obstructive pulmonary disease (COPD). c-FLIP is a critical anti-cell deat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6915968f6d88217b8afcc933e654cf59
https://doi.org/10.36648/2472-1646.5.1.59

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Biochemistry of Apoptosis

Autor: Kartlaşmış, Kezban, Kökbaş, Umut, Kayrın, Levent

Publikováno v: Arsiv Kaynak Tarama Dergisi, Vol 25, Iss 1, Pp 52-69 (2016)
Volume: 25, Issue: 1 52-69
Arşiv Kaynak Tarama Dergisi

Apoptosis is one of the cell death types which is studied for a long times. During the last 30 years many investigation were carried out for this type cell death and the molecular mechanism of this self destruction of live cell were explained. Whethe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7f18a4b2e0baff2d9f2cbb5cf0f5ec9a
http://www.scopemed.org/fulltextpdf.php?mno=190438

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Akademický článek

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Akademický článek

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The Inhibitor of Death Receptor Signaling, Flice-Inhibitory Protein Defines a New Class of Tumor Progression Factors

Autor: Valentina Screpanti, Mounira Djerbi, Bjarne Bogen, Alf Grandien, Peter Biberfeld, Anca I. Catrina

Publikováno v: The Journal of Experimental Medicine

Death receptor–mediated apoptosis can be modulated by several antiapoptotic proteins, such as the FLICE (FADD [Fas-associated death domain]-like IL-1β–converting enzyme)-inhibitory proteins (FLIPs). The FLIP family includes both cellular and vir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c00630b2e4752906457dc781487194
https://doi.org/10.1084/jem.190.7.1025

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Substituted 4-(thiazol-5-yl)-2-(phenylamino)pyrimidines are highly active CDK9 inhibitors: synthesis, X-ray crystal structures, structure-activity relationship, and anticancer activities

Autor: Jane A. Endicott, Chris Pepper, Alison J. Hole, Abdullahi Y. Abbas, Shenhua Shi, Frankie Lam, Shudong Wang, Martin E.M. Noble, Sonja Baumli, Hao Shao, Xiangrui Liu, David W. Foley, Shiliang Huang, Peter Fischer

Publikováno v: Journal of Medicinal Chemistry

Cancer cells often have a high demand for antiapoptotic proteins in order to resist programmed cell death. CDK9 inhibition selectively targets survival proteins and reinstates apoptosis in cancer cells. We designed a series of 4-thiazol-2- anilinopyr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ca38616b46173ee2f7407ba2de20a5
https://pubmed.ncbi.nlm.nih.gov/23301767

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The anti-apoptotic Bcl-x(L) protein, a new piece in the puzzle of cytochrome c interactome

Autor: Paola Turano, Soizic Chevance, Daniela Lalli, Ivano Bertini, Rebecca Del Conte

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18329 (2011)
PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (4), pp.e18329. ⟨10.1371/journal.pone.0018329⟩
PLoS ONE, 2011, 6 (4), pp.e18329. ⟨10.1371/journal.pone.0018329⟩

International audience; A structural model of the adduct between human cytochrome c and the human anti-apoptotic protein Bcl-x(L), which defines the protein-protein interaction surface, was obtained from solution NMR chemical shift perturbation data.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29947da67af1934e91520eabdddaa0e7
http://europepmc.org/articles/PMC3080137?pdf=render

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