Zobrazeno 1 - 10
of 337
pro vyhledávání: '"ANTHONY J. WINDEBANK"'
Autor:
Mohamad Bydon, Wenchun Qu, F. M. Moinuddin, Christine L. Hunt, Kristin L. Garlanger, Ronald K. Reeves, Anthony J. Windebank, Kristin D. Zhao, Ryan Jarrah, Brandon C. Trammell, Sally El Sammak, Giorgos D. Michalopoulos, Konstantinos Katsos, Stephen P. Graepel, Kimberly L. Seidel-Miller, Lisa A. Beck, Ruple S. Laughlin, Allan B. Dietz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Intrathecal delivery of autologous culture-expanded adipose tissue-derived mesenchymal stem cells (AD-MSC) could be utilized to treat traumatic spinal cord injury (SCI). This Phase I trial (ClinicalTrials.gov: NCT03308565) included 10 patien
Externí odkaz:
https://doaj.org/article/58b0acd07326464a9f8c65e7ce63ed73
Autor:
Mohamad Bydon, Wenchun Qu, F. M. Moinuddin, Christine L. Hunt, Kristin L. Garlanger, Ronald K. Reeves, Anthony J. Windebank, Kristin D. Zhao, Ryan Jarrah, Brandon C. Trammell, Sally El Sammak, Giorgos D. Michalopoulos, Konstantinos Katsos, Stephen P. Graepel, Kimberly L. Seidel-Miller, Lisa A. Beck, Ruple S. Laughlin, Allan B. Dietz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/296a648e5b93480eb9ccacd2491a8ea0
Autor:
Ahad M. Siddiqui, Riazul Islam, Carlos A. Cuellar, Jodi L. Silvernail, Bruce Knudsen, Dallece E. Curley, Tammy Strickland, Emilee Manske, Parita T. Suwan, Timur Latypov, Nafis Akhmetov, Shuya Zhang, Priska Summer, Jarred J. Nesbitt, Bingkun K. Chen, Peter J. Grahn, Nicolas N. Madigan, Michael J. Yaszemski, Anthony J. Windebank, Igor A. Lavrov
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Here, we report the effect of newly regenerated axons via scaffolds on reorganization of spinal circuitry and restoration of motor functions with epidural electrical stimulation (EES). Motor recovery was evaluated for 7 weeks after spinal tr
Externí odkaz:
https://doaj.org/article/67d449c107bc43249dbc266d5bec3d00
Autor:
Nicolas N. Madigan, Michael J. Polzin, Gaofeng Cui, Teerin Liewluck, Mohammad H. Alsharabati, Christopher J. Klein, Anthony J. Windebank, Georges Mer, Margherita Milone
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract The MYH2 gene encodes the skeletal muscle myosin heavy chain IIA (MyHC-IIA) isoform, which is expressed in the fast twitch type 2A fibers. Autosomal dominant or recessive pathogenic variants in MYH2 lead to congenital myopathy clinically fea
Externí odkaz:
https://doaj.org/article/3a44d8dc51b44329ad0732315017e487
Autor:
Ashley A. Krull, Deborah O. Setter, Tania F. Gendron, Sybil C. L. Hrstka, Michael J. Polzin, Joseph Hart, Amel Dudakovic, Nicolas N. Madigan, Allan B. Dietz, Anthony J. Windebank, Andre J. van Wijnen, Nathan P. Staff
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Mesenchymal stromal cells (MSCs) have been studied with increasing intensity as clinicians and researchers strive to understand the ability of MSCs to modulate disease progression and promote tissue regeneration. As MSCs are used
Externí odkaz:
https://doaj.org/article/47692b6a9c6541b9a0f6a8f7dadecf99
Autor:
Alexandra J. Greenberg-Worisek, Katherine E. Cornelius, Luz Cumba Garcia, Felicity T. Enders, Nilay D. Shah, Anthony J. Windebank
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 8-15 (2020)
As the pace of biomedical innovation rapidly evolves, there is a need to train researchers to understand regulatory science challenges associated with clinical translation. We describe a pilot course aimed at addressing this need delivered jointly th
Externí odkaz:
https://doaj.org/article/a7fd22d72ee949f694c431165f72b77c
Publikováno v:
Fly, Vol 12, Iss 3-4, Pp 174-182 (2018)
Drosophila melanogaster has recently been developed as a simple, in vivo, genetic model of chemotherapy-induced peripheral neuropathy. Flies treated with the chemotherapy agent cisplatin display both a neurodegenerative phenotype and cell death in ra
Externí odkaz:
https://doaj.org/article/580f71c2a27e4b26a3faa9e84a2fd1a8
Autor:
Jason J. Tang, Jewel L. Podratz, Miranda Lange, Heidi J. Scrable, Mi-Hyeon Jang, Anthony J. Windebank
Publikováno v:
Molecular Brain, Vol 10, Iss 1, Pp 1-13 (2017)
Abstract Mechano growth factor (MGF) is a splice variant of IGF-1 first described in skeletal muscle. MGF induces muscle cell proliferation in response to muscle stress and injury. In control mice we found endogenous expression of MGF in neurogenic a
Externí odkaz:
https://doaj.org/article/f9171dbff1904323a7afe14e4cde3b55
Autor:
Craig M. Nelson, Vanda A. Lennon, Han Lee, Randall G. Krug, Aichurok Kamalova, Nicolas N. Madigan, Karl J. Clark, Anthony J. Windebank, John R. Henley
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Following injury, the mammalian spinal cord forms a glial scar and fails to regenerate. In contrast, vertebrate fish spinal cord tissue regenerates significantly to restore function. Cord transection in zebrafish (Danio rerio) initially causes paraly
Externí odkaz:
https://doaj.org/article/f67ee13612df40c685a96d539d7e7052
Autor:
Ahad M. Siddiqui, Rosa Brunner, Gregory M. Harris, Alan Lee Miller, Brian E. Waletzki, Ann M. Schmeichel, Jean E. Schwarzbauer, Jeffrey Schwartz, Michael J. Yaszemski, Anthony J. Windebank, Nicolas N. Madigan
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 479 (2021)
Spinal cord injury (SCI) results in cell death, demyelination, and axonal loss. The spinal cord has a limited ability to regenerate, and current clinical therapies for SCI are not effective in helping promote neurologic recovery. We have developed a
Externí odkaz:
https://doaj.org/article/2a37287371dc43eb81a0436be9a73352