Výsledky vyhledávání - "ANTHELMINTIC RESISTANCE"

Akademický článek

Benzimidazole resistance-associated mutations improve the in silico dimerization of hookworm tubulin: An additional resistance mechanism

Autor: Jan Clyden B. Tenorio, Muhammad Fikri Heikal, Alok Kafle, Prasert Saichua, Sutas Suttiprapa

Publikováno v: Veterinary World, Vol 17, Iss 12, Pp 2736-2746 (2024)

Background and Aim: Mutations in the β-tubulin genes of helminths confer benzimidazole (BZ) resistance by reducing the drug’s binding efficiency to the expressed protein. However, the effects of these resistance-associated mutations on tubulin dim

Externí odkaz: https://doaj.org/article/cadd980feeb8443e9014b960930c5a3a

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Akademický článek

Differences in constitutive gene expression of cytochrome P450 enzymes and ATP-binding cassette transporter gene expression between a susceptible and a highly macrocyclic lactone-resistant Haemonchus contortus isolate in the absence of drug-inducible expression

Autor: Natalie Jakobs, Sandro Andreotti, Sabrina Ramünke, Georg von Samson-Himmelstjerna, Jürgen Krücken

Publikováno v: Parasites & Vectors, Vol 17, Iss 1, Pp 1-19 (2024)

Abstract Background Anthelmintic resistance in ruminants is a widespread problem that has a severe impact on productivity and animal welfare. The helminth Haemonchus contortus is generally considered the most important parasite in small ruminants due

Externí odkaz: https://doaj.org/article/8263fc4eb6e347e2aef187bb82a147e9

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Akademický článek

Treatment ineffectiveness towards Haemonchus contortus is highly prevalent in sheep and goat farms of North-Eastern Italy

Autor: Anna Maurizio, Giorgia Dotto, Antonia Fasoli, Francesco Gaio, Sara Petratti, Alice Pertile, Cinzia Tessarin, Erica Marchiori, Debora Dellamaria, Jaroslav Vadlejch, Rudi Cassini

Publikováno v: BMC Veterinary Research, Vol 20, Iss 1, Pp 1-7 (2024)

Abstract Background Anthelmintic resistance (AR) is a global threat to grazing livestock farming. In Italy, anthelmintic efficacy remains high compared to other European countries, but many parts of the country haven’t been investigated yet. Local

Externí odkaz: https://doaj.org/article/782087ce09b448a380f8d31e84039022

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Akademický článek

High rates of benzimidazole-resistance-associated alleles in Haemonchus contortus and detection of resistance against macrocyclic lactones in strongylids from German alpaca herds

Autor: Barbara Hinney, Sandra Wiedermann, Xenia Vaneev, Katharina Muhm, Anja Joachim, Thomas Wittek

Publikováno v: Parasites & Vectors, Vol 17, Iss 1, Pp 1-7 (2024)

Abstract The population of South American camelids (SAC) has been steadily growing in Europe, where they are confronted with the regional endoparasite population of ruminants. As there are no anthelmintic drugs registered for use against nematode inf

Externí odkaz: https://doaj.org/article/92d9c51f355a48d492490b742012e014

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Akademický článek

Molecular detection of gene encodes a β-tubulin protein in Haemonchus contortus in sheep in Al-Qadisiyah province, Iraq

Autor: Athraa N. Abed, Monyer A. Al-Fatlawi

Publikováno v: Iraqi Journal of Veterinary Sciences, Vol 38, Iss 3, Pp 671-675 (2024)

β-tubulin protein is essential to parasitic resistance against widely used anthelmintic drugs. Many world countries are facing major challenges due to the failure of anthelmintic drugs, due to resistance, to eliminate parasitic infection in differen

Externí odkaz: https://doaj.org/article/7f0190bcc07b4da5bb05cdac0662e5a4

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Akademický článek

Efficacy of fenbendazole against gastrointestinal nematodes in naturally infected goats in Maputo Province, Mozambique using in vivo, in vitro and molecular assessment

Autor: Edna F.X. Guinda, Sonia M.S. Afonso, Stefan Fiedler, Eric R. Morgan, Sabrina Ramünke, Marc Borchert, Alsácia Atanásio, Bettencourt P.S. Capece, Jürgen Krücken, Georg von Samson-Himmelstjerna

Publikováno v: International Journal for Parasitology: Drugs and Drug Resistance, Vol 27, Iss , Pp 100572- (2025)

Anthelmintic resistance occurs worldwide in strongyles of ruminants but data from low-income countries are sparse and rarely apply most up to date methods, while effects of management practices in these countries are poorly documented. In Mozambique,

Externí odkaz: https://doaj.org/article/eaef0b3f83e0421a837d33b7a0cfb11a

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