Zobrazeno 1 - 10
of 22
pro vyhledávání: '"ANT, adenine nucleotide translocase"'
Autor:
Shaoping Guan, Xinping Liu, Richard W. Gross, Harold F. Sims, Beverly Gibson Dilthey, Sung Ho Moon
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100052-(2021)
Journal of Lipid Research, Vol 62, Iss, Pp 100052-(2021)
High-fat (HF) diet–induced obesity precipitates multiple metabolic disorders including insulin resistance, glucose intolerance, oxidative stress, and inflammation, resulting in the initiation of cell death programs. Previously, we demonstrated muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac707a6479481fac40eba79f66d3ab5b
http://europepmc.org/articles/PMC8010217
http://europepmc.org/articles/PMC8010217
Publikováno v:
Redox Biology, Vol 18, Iss, Pp 279-294 (2018)
Redox Biology
Redox Biology
Tau is a key protein for microtubule stability; however, post-translationally modified tau contributes to neurodegenerative diseases by forming tau aggregates in the neurons. Previous reports from our group and others have shown that pathological for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2f553ad0342b33fd6d09fcde65ae42
https://doi.org/10.1016/j.redox.2018.07.010
https://doi.org/10.1016/j.redox.2018.07.010
Publikováno v:
Biochemistry and Biophysics Reports, Vol 26, Iss, Pp 100928-(2021)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
VWA8 (Von Willebrand A Domain Containing Protein 8) is a AAA+ ATPase that is localized to the mitochondrial matrix and is widely expressed in highly energetic tissues. Originally found to be higher in abundance in livers of mice fed a high fat diet,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09823394b9e2df418df83daf7d8171c
https://doi.org/10.1016/j.bbrep.2021.100928
https://doi.org/10.1016/j.bbrep.2021.100928
Autor:
Fabio Di Lisa, Paolo Bernardi
Publikováno v:
Journal of Molecular and Cellular Cardiology
The mitochondrial permeability transition (PT) – an abrupt increase permeability of the inner membrane to solutes – is a causative event in ischemia–reperfusion injury of the heart, and the focus of intense research in cardioprotection. The PT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48153568f5aefe237a4b56960be7b044
http://europepmc.org/articles/PMC4294587
http://europepmc.org/articles/PMC4294587
Publikováno v:
Journal of Molecular and Cellular Cardiology
We critically assess the proposal that succinate-fuelled reverse electron flow (REF) drives mitochondrial matrix superoxide production from Complex I early in reperfusion, thus acting as a key mediator of ischemia/reperfusion (IR) injury. Real-time s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634c2fd43b4e26a7f7a1dfc2fc12acd4
https://pubmed.ncbi.nlm.nih.gov/28689004
https://pubmed.ncbi.nlm.nih.gov/28689004
Publikováno v:
Cell Calcium
Graphical abstract
The mitochondrial permeability transition pore (mPTP) has long been known to have a role in mitochondrial calcium (Ca2+) homeostasis under pathological conditions as a mediator of the mitochondrial permeability transition and
The mitochondrial permeability transition pore (mPTP) has long been known to have a role in mitochondrial calcium (Ca2+) homeostasis under pathological conditions as a mediator of the mitochondrial permeability transition and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c778ebd2bd98fa51e3e32528cffb5ed7
http://europepmc.org/articles/PMC4074345
http://europepmc.org/articles/PMC4074345
Publikováno v:
Redox Biology
Redox Biology, Vol 2, Iss C, Pp 224-233 (2014)
Redox Biology, Vol 2, Iss C, Pp 224-233 (2014)
Mitochondrial toxicity is increasingly being implicated as a contributing factor to many xenobiotic-induced organ toxicities, including skeletal muscle toxicity. This has necessitated the need for predictive in vitro models that are able to sensitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797228fc9bd46940fbbd75c188da6a9b
https://doi.org/10.1016/j.redox.2013.12.028
https://doi.org/10.1016/j.redox.2013.12.028
Publikováno v:
Biochemical Journal
Mitochondrial protein tyrosine phosphorylation is an important mechanism for the modulation of mitochondrial functions. In the present study, we have identified novel substrates of c-Src in mitochondria and investigated their function in the regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e018b65ec457e1f3873f06359710a897
https://doi.org/10.1042/bj20120509
https://doi.org/10.1042/bj20120509
Publikováno v:
Mitochondrion
Phosphate activation of the mitochondrial permeability transition pore (MPTP) opening is well-documented and could involve the phosphate carrier (PiC) that we have proposed is the pore's cyclophilin-D binding component. However, others have reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f575a22a3e038b074f4eadf378fa27
http://europepmc.org/articles/PMC3281194
http://europepmc.org/articles/PMC3281194
Publikováno v:
Biochemical Journal
Oxidized cytochrome c is a powerful superoxide scavenger within the mitochondrial IMS (intermembrane space), but the importance of this role in situ has not been well explored. In the present study, we investigated this with particular emphasis on wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1228d43589184d32e9c71d29b2836c80
http://europepmc.org/articles/PMC3195442
http://europepmc.org/articles/PMC3195442