Zobrazeno 1 - 10
of 140
pro vyhledávání: '"ANNALEN BLECKMANN"'
Autor:
Suganja Chandrabalan, Linh Dang, Uwe Hansen, Melanie Timmen, Corinna Wehmeyer, Richard Stange, Tim Beißbarth, Claudia Binder, Annalen Bleckmann, Kerstin Menck
Publikováno v:
Biological Procedures Online, Vol 26, Iss 1, Pp 1-17 (2024)
Abstract Background Osteoclasts are the tissue-specific macrophage population of the bone and unique in their bone-resorbing activity. Hence, they are fundamental for bone physiology in health and disease. However, efficient protocols for the isolati
Externí odkaz:
https://doaj.org/article/1c6c35f19f30456b964c2af20178a2ad
Autor:
Anna-Maria Diedrich, Assal Daneshgar, Peter Tang, Oliver Klein, Annika Mohr, Olachi A. Onwuegbuchulam, Sabine von Rueden, Kerstin Menck, Annalen Bleckmann, Mazen A. Juratli, Felix Becker, Igor M. Sauer, Karl H. Hillebrandt, Andreas Pascher, Benjamin Struecker
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Background The extracellular matrix (ECM) is a three-dimensional network of proteins that encases and supports cells within a tissue and promotes physiological and pathological cellular differentiation and functionality. Understanding the co
Externí odkaz:
https://doaj.org/article/184b7542c395420292ac63157f983099
Autor:
Nadja Schöne, Marcel Kemper, Kerstin Menck, Georg Evers, Carolin Krekeler, Arik Bernard Schulze, Georg Lenz, Eva Wardelmann, Claudia Binder, Annalen Bleckmann
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Immunotherapy has revolutionized the treatment of patients with non‐small cell lung cancer (NSCLC). High expression of tissue PD‐L1 (tPD‐L1) is currently the only approved biomarker for predicting treatment response. However, even tPD
Externí odkaz:
https://doaj.org/article/33b401bedfa54e9ba0cbe7aa50c5a449
Autor:
Ruben Evertz, Christine Diehl, Katharina Gödde, Miroslava Valentova, Tania Garfias-Veitl, Tobias R. Overbeck, Friederike Braulke, Alessia Lena, Sara Hadzibegovic, Annalen Bleckmann, Ulrich Keller, Ulf Landmesser, Alexander O. König, Gerd Hasenfuss, Andreas Schuster, Markus S. Anker, Stephan von Haehling
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Maintaining cancer patients’ exercise capacity and therefore patients’ ability to live a self-determined life is of huge importance, but little is known about major determinants. We sought to identify determinants of exercise capacity in
Externí odkaz:
https://doaj.org/article/714f73e5313b4f03983b1731284c9e65
Autor:
Barnabas Irmer, Janes Efing, Lea Elisabeth Reitnauer, Allegra Angenendt, Saskia Heinrichs, Antonia Schubert, Matthias Schulz, Claudia Binder, Joke Tio, Uwe Hansen, Christiane Geyer, Mirjam Gerwing, Annalen Bleckmann, Kerstin Menck
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Extracellular vesicles (EVs) harbor a plethora of different biomolecules, which they can transport across cells. In cancer, tumor-derived EVs thereby support the creation of a favorable tumor microenvironment. So far, EV uptake an
Externí odkaz:
https://doaj.org/article/2d48326b02b54a75a3384e4a27350f60
Autor:
Ruben Evertz, Katharina Gödde, Christine Diehl, Miroslava Valentova, Tania Garfias‐Veitl, Friederike Braulke, Gerald G. Wulf, Tobias R. Overbeck, Annalen Bleckmann, Alexander O. König, Pia Weinländer, Sophia Potthoff, Sara Hadzibegovic, Alessia Lena, Ulrich Keller, Ulf Landmesser, Andreas Schuster, Markus S. Anker, Gerd Hasenfuß, Stephan vonHaehling
Publikováno v:
ESC Heart Failure, Vol 10, Iss 1, Pp 167-176 (2023)
Abstract Aims Maintaining quality of life (QoL) in patients with cancer has gathered significant interest, but little is known about its major determinants. We sought to identify determinants of QoL in patients undergoing cancer treatment as well as
Externí odkaz:
https://doaj.org/article/586093e844e2498bae29c65f7e2a7ebf
Autor:
Johannes Robert Fleischer, Alexandra Maria Schmitt, Gwendolyn Haas, Xingbo Xu, Elisabeth Maria Zeisberg, Hanibal Bohnenberger, Stefan Küffer, Laure-Anne Teuwen, Philipp Johannes Karras, Tim Beißbarth, Annalen Bleckmann, Mélanie Planque, Sarah-Maria Fendt, Peter Vermeulen, Michael Ghadimi, Joanna Kalucka, Tiago De Oliveira, Lena-Christin Conradi
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-22 (2023)
Abstract Background Colorectal cancer liver metastases (CRCLM) are associated with a poor prognosis, reflected by a five-year survival rate of 14%. Anti-angiogenic therapy through anti-VEGF antibody administration is one of the limited therapies avai
Externí odkaz:
https://doaj.org/article/380114cc6bdc4ae19d7ea19ff089eb9c
Autor:
Julia Felicitas Leni Koenig, Thomas Asendorf, Alfred Simon, Annalen Bleckmann, Lorenz Truemper, Gerald Wulf, Tobias R. Overbeck
Publikováno v:
BMC Palliative Care, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background The advance directive represents patients’ health care choices and fosters patients’ autonomy. Nevertheless, understanding patients’ wishes based on the information provided in advance directives remains a challenge for heal
Externí odkaz:
https://doaj.org/article/8ded9082ab8e4d5c8e4a73f1aae9c206
Autor:
Göran Ramin Boeckel, Silke Dorothea Hölscher, Christin Bürger, Torid Jacob, Carolin Krekeler, Evgenii Shumilov, Christian Reicherts, Annalen Bleckmann, Georg Lenz, Richard Vollenberg, Phil-Robin Tepasse
Publikováno v:
Current Oncology, Vol 29, Iss 4, Pp 2312-2325 (2022)
Patients with hematologic malignancies are at high risk of exacerbated condition and higher mortality from coronavirus disease 2019 (COVID-19). Bamlanivimab, casirivimab/imdevimab combination, and sotrovimab are monoclonal antibodies (mABs) that can
Externí odkaz:
https://doaj.org/article/8cedc6fdf00745f9891b1e55c41679e6
Autor:
Kerstin Menck, Saskia Heinrichs, Darius Wlochowitz, Maren Sitte, Helen Noeding, Andreas Janshoff, Hannes Treiber, Torben Ruhwedel, Bawarjan Schatlo, Christian von der Brelie, Stefan Wiemann, Tobias Pukrop, Tim Beißbarth, Claudia Binder, Annalen Bleckmann
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Breast cancer has been associated with activation of the WNT signaling pathway, although no driver mutations in WNT genes have been found yet. Instead, a high expression of the alternative WNT receptor ROR2 was observed, in partic
Externí odkaz:
https://doaj.org/article/d0a5a0c967764391a19be071ba9a9dca