Zobrazeno 1 - 10
of 68
pro vyhledávání: '"ANIL SADARANGANI"'
Autor:
Jean Y.J. Wang, Helena L. Borges, Lars Eckmann, Michael E. Ramirez, Priya Sridevi, Anil Sadarangani, Rossana C. Soletti, Jinbo Han
PDF file - 2529K, S1 Similar levels of TUNEL-positive cells were observed in the splenic tissue sections from Rb+/+ and RbMI/MI mice at 24 hr after PBS (Veh) or TNF-α i.p. injection. Scale bar: 50 μm. **p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4a527d0bf603d8601b2be7dc7f67b1
https://doi.org/10.1158/1541-7786.22509795
https://doi.org/10.1158/1541-7786.22509795
Autor:
Jean Y.J. Wang, Helena L. Borges, Lars Eckmann, Michael E. Ramirez, Priya Sridevi, Anil Sadarangani, Rossana C. Soletti, Jinbo Han
Tumor necrosis factor (TNF)-α promotes tumor development under chronic inflammation. Because TNF also activates caspase-8, selective inhibition of TNF-induced extrinsic apoptosis would be required for inflammation-associated tumor growth. In a mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8603c131ef1fa8068dbcc5396ea06415
https://doi.org/10.1158/1541-7786.c.6539400
https://doi.org/10.1158/1541-7786.c.6539400
Autor:
ANIL SADARANGANI, ANA MARÍA SALGADO, SUMIE KATO, MAURICIO PINTO, ANDRÉS CARVAJAL, CAROLINA MONSO, GARETH I OWEN, PILAR VIGIL
Publikováno v:
Biological Research, Vol 38, Iss 2-3, Pp 245-258 (2005)
Estrogen and progestin combination in hormone replacement therapy (HRT) increases the incidence of breast cancer, but decreases the endometrial cancer risk of unopposed estrogen. Therefore, a SERM such as Tibolone, that delivers the beneficial, but n
Externí odkaz:
https://doaj.org/article/f68dde2764764f77b3f8b517ebea6a0f
Autor:
Wenxue Ma, Alejandro Gutierrez, Daniel J Goff, Ifat Geron, Anil Sadarangani, Christina A M Jamieson, Angela C Court, Alice Y Shih, Qingfei Jiang, Christina C Wu, Kang Li, Kristen M Smith, Leslie A Crews, Neil W Gibson, Ida Deichaite, Sheldon R Morris, Ping Wei, Dennis A Carson, A Thomas Look, Catriona H M Jamieson
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39725 (2012)
Leukemia initiating cells (LIC) contribute to therapeutic resistance through acquisition of mutations in signaling pathways, such as NOTCH1, that promote self-renewal and survival within supportive niches. Activating mutations in NOTCH1 occur commonl
Externí odkaz:
https://doaj.org/article/6a6e685aeb1a4e9ea677136b58ec1e0c
Autor:
Catriona Jamieson, Maurizio Pellecchia, Wenxue Ma, Lawrence S.B. Goldstein, Alice Y. Shih, Maryla Krajewska, Kelly A. Frazer, Janine M. Low-Marchelli, Anil Sadarangani, John C. Reed, Karen Messer, Ifat Geron, Minya Pu, Christian L. Barrett, Dayong Zhai, Sheldon R. Morris, Lei Bao, Daniel Goff, Hye Jung E. Chun, Jessica M. Rusert, Thomas J. Hudson, Angela Court Recart, Kim Hien T. Dao, Peggy Wentworth, Mark D. Minden, Ryan Chuang, Christina Jamieson, Jason Gotlib, Kristen M. Smith, Jun Wei, Kamran Shazand, Giovanni Martinelli, Heather Leu, Marco A. Marra, Larisa Balaian
Publikováno v:
Cell Stem Cell. 12(3):316-328
SummaryLeukemia stem cells (LSCs) play a pivotal role in the resistance of chronic myeloid leukemia (CML) to tyrosine kinase inhibitors (TKIs) and its progression to blast crisis (BC), in part, through the alternative splicing of self-renewal and sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcec4d248dc5222d4c3b8491f2ea003d
Autor:
Anil Sadarangani, Priya Sridevi, Rossana C. Soletti, Lars Eckmann, Jean Y. J. Wang, Jinbo Han, Michael E. Ramirez, Helena L. Borges
Publikováno v:
Molecular Cancer Research. 11:207-218
Tumor necrosis factor (TNF)-α promotes tumor development under chronic inflammation. Because TNF also activates caspase-8, selective inhibition of TNF-induced extrinsic apoptosis would be required for inflammation-associated tumor growth. In a mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aad1f3967fbbb2dafdb5e3f8141ccdb
https://doi.org/10.1158/1541-7786.mcr-12-0670
https://doi.org/10.1158/1541-7786.mcr-12-0670
Autor:
Anil Sadarangani, Maria A. Zipeto, Leslie Crews, Cayla Mason, Daniel Goff, Mark D. Minden, Sheldon R. Morris, Marco A. Marra, Russell Wall, Kelly A. Frazer, Hye Jung E. Chun, Angela C. Court, Gabriel Pineda, Qingfei Jiang, Larisa Balaian, Ifat Geron, Nathaniel Delos Santos, Catriona Jamieson, Maurizio Pellecchia, Christian L. Barrett
Publikováno v:
Cell stem cell, vol 19, iss 2
Post-transcriptional adenosine-to-inosine RNA editing mediated by adenosine deaminase acting on RNA1 (ADAR1) promotes cancer progression and therapeutic resistance. However, ADAR1 editase-dependent mechanisms governing leukemia stem cell (LSC) genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3959f35de561890f64dd896e3040d7ee
https://escholarship.org/uc/item/04z5f0f3
https://escholarship.org/uc/item/04z5f0f3
Publikováno v:
Systems Biology in Reproductive Medicine. 56:318-326
The aim of this study is to compare the expression patterns of tyrosine kinases and their ligand activators between matched myometrium and leiomyoma tissues. Total RNA extracted from 42 pairs of matched leiomyomal and adjacent myometrial tissues were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36b7d81413f86dc27de75ac2ad72405
https://doi.org/10.3109/19396361003646109
https://doi.org/10.3109/19396361003646109
Autor:
Anil Sadarangani, Daniel Goff, Annelie E. Abrahamsson Schairer, Catriona Jamieson, Todd VanArsdale, Richard A. Moore, Karen Messer, Lei Bao, Marco A. Marra, Thomas J. Hudson, Ifat Geron, Michael John Munchhof, Minya Pu, Kathleen M. Lennon, Russell Wall, Mark D. Minden, Sheldon R. Morris, Gabriel Pineda, Angela C. Court, Tannishtha Reya, Amy Jackson-Fisher, John Douglas Mcpherson, Hanna K. A. Mikkola, Sacha L. Prashad, Alice Shih, Hye Jung E. Chun
Publikováno v:
Journal of Translational Medicine
Journal of translational medicine, vol 13, iss 1
Sadarangani, A; Pineda, G; Lennon, KM; Chun, HJ; Shih, A; Schairer, AE; et al.(2015). GLI2 inhibition abrogates human leukemia stem cell dormancy. Journal of Translational Medicine, 13(1), 1. doi: 10.1186/s12967-015-0453-9. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/1176d581
Journal of translational medicine, vol 13, iss 1
Sadarangani, A; Pineda, G; Lennon, KM; Chun, HJ; Shih, A; Schairer, AE; et al.(2015). GLI2 inhibition abrogates human leukemia stem cell dormancy. Journal of Translational Medicine, 13(1), 1. doi: 10.1186/s12967-015-0453-9. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/1176d581
Background Dormant leukemia stem cells (LSC) promote therapeutic resistance and leukemic progression as a result of unbridled activation of stem cell gene expression programs. Thus, we hypothesized that 1) deregulation of the hedgehog (Hh) stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2ca942bcd7dd390925140e5a54b08c
https://doi.org/10.1186/s12967-015-0453-9
https://doi.org/10.1186/s12967-015-0453-9
Autor:
Larisa Balaian, Michael D. Burkart, Anna A. Kulidjian, James J. La Clair, Nathaniel Delos Santos, Reymundo Villa, Sheldon R. Morris, Maria A. Zipeto, Catriona Jamieson, Edward D. Ball, Heather Leu, Anil Sadarangani, Angela C. Court, Leslie Crews, Rainer Storb
Publikováno v:
Cancer Research. 76:915-915
Introduction: Human bone marrow aging is typified by decreased cellularity, stem cell exhaustion and myeloid lineage bias that may set the stage for development of myeloid malignancies. Secondary AML (sAML) is a malignancy that has been associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e9a9e00dfd0a63d373a6a62d97836f
https://doi.org/10.1158/1538-7445.am2016-915
https://doi.org/10.1158/1538-7445.am2016-915