Induced hypernatremia in patients with moderate-to-severe ARDS: a randomized controlled study

Autor: Shailesh Bihari, Shivesh Prakash, Dani L. Dixon, Elena Cavallaro, Andrew D. Bersten

Publikováno v: Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-12 (2021)

Abstract Background Induced hypernatremia and hyperosmolarity is protective in animal models of lung injury. We hypothesized that increasing and maintaining plasma sodium between 145 and 150 mmol/l in patients with moderate-to-severe ARDS would be sa

Externí odkaz: https://doaj.org/article/ba1930534f84443087cc737cf7778861

Bolus intravenous 0.9% saline leads to interstitial permeability pulmonary edema in healthy volunteers

Autor: Elena Cavallaro, Shailesh Bihari, Hanmo Li, Ubbo F Wiersema, Dani-Louise Dixon, David Schembri, Andrew D. Bersten

Publikováno v: European Journal of Applied Physiology. 121:3409-3419

Bolus intravenous administration of 0.9% saline has been associated with the development of pulmonary edema, and increased mortality. An animal model has previously demonstrated that rapid intravenous administration of 0.9% saline was associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2e4c6bc3377a2b3fe262e26af7e734c
https://doi.org/10.1007/s00421-021-04805-2

Acute respiratory distress syndrome phenotypes with distinct clinical outcomes in PHARLA trial cohort

Autor: Shailesh Bihari, Carolyn S. Calfee, Intensive, Eldho Paul, Pratik Sinha, Shay McGuinness, Alistair Nichol, Dani Dixon, Cardiothoracic, contributed equally to manuscript, Carol L. Hodgson, Andrew D. Bersten

Publikováno v: Critical Care and Resuscitation. 23:163-170

Background: The Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure (PHARLAP) randomised controlled trial compared an open lung ventilation strategy with control ventilation, and found that open lung ventilation did not reduce the nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f92479e252dc902dc758838401b7ec5
https://doi.org/10.51893/2021.2.oa3

Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery

Autor: Karine E. Manera, Armando Teixeira-Pinto, Tess E Cooper, Peter Horby, Saad Nseir, Lilia Cervantes, Andrea Matus Gonzalez, Tom Snelling, Alan R Smyth, Yasser Sakr, Simon A. Carter, Dale M. Needham, Andrew D. Bersten, Paula R Williamson, Giovanni F.M. Strippoli, Luciano Cesar Pontes Azevedo, Antoni Torres, Jonathan C. Craig, Elyssa Hannan, Eduardo Lorca, John C. Marshall, Sally Crowe, Amanda Baumgart, Junhua Zhang, Derek P. Chew, Mervyn Mer, Angela Ju, Sangeeta Mehta, Pedro Póvoa, Ivor S. Douglas, Mark Reid, Deena Lynch, Allison Tong, Anne McKenzie, Ella Flemyng, Steve Webb, Andrea K. Viecelli, A. John Simpson, Julian H Elliott, Martin Howell, Ning Shen, Nicole Evangelidis, Laila Woc-Colburn, Tari Turner, Jaehee Lee, Andrew Conway Morris

Publikováno v: Critical Care Medicine
Tong, A, Baumgart, A, Evangelidis, N, Viecelli, A K, Carter, S A, Azevedo, L C, Cooper, T, Bersten, A, Cervantes, L, Chew, D P, Crowe, S, Douglas, I S, Flemyng, E, Elliott, J H, Hannan, E, Horby, P, Howell, M, Ju, A, Lee, J, Lorca, E, Lynch, D, Manera, K E, Marshall, J C, Gonzalez, A M, McKenzie, A, Mehta, S, Mer, M, Morris, A C, Needham, D M, Nseir, S, Povoa, P, Reid, M, Sakr, Y, Shen, N, Smyth, A R, Simpson, A J, Snelling, T, Strippoli, G F M, Teixeira-Pinto, A, Torres, A, Turner, T, Webb, S, Williamson, P R, Woc-Colburn, L, Zhang, J, Craig, J C & COVID-19-Core Outcomes Set Investigators 2021, ' Core Outcome Measures for Trials in People With Coronavirus Disease 2019 : Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery ', Critical Care Medicine, vol. 49, no. 3, pp. 503-516 . https://doi.org/10.1097/CCM.0000000000004817

Supplemental Digital Content is available in the text.
OBJECTIVES: Respiratory failure, multiple organ failure, shortness of breath, recovery, and mortality have been identified as critically important core outcomes by more than 9300 patients, h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0c2eb88ae3be14864548f3a9e896e4
http://europepmc.org/articles/PMC7892260

ICU shift related effects on sleep, fatigue and alertness levels

Autor: A. Venkatapathy, Shivesh Prakash, Shailesh Bihari, E. Everest, Andrew D. Bersten

Publikováno v: Occupational Medicine. 70:107-112

Background Shift work may lead to suboptimal sleep resulting in impaired alertness, and lowered performance levels, all of which can lead to medical errors. Aims To examine fatigue, sleepiness and behavioural alertness prospectively in a tertiary lev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6454ffda73f060a0f3718bcf7476d51
https://doi.org/10.1093/occmed/kqaa013