Prevalence and associations of chronic kidney disease among antiretroviral therapy-naïve persons living with HIV in Lagos, Nigeria

Autor: Oluwatosin Olaseni Odubela, Nkiruka Nnonyelum Odunukwe, Nasheeta Peer, Adesola Zaidat Musa, Babatunde Lawal Salako, Andre Pascal Kengne

Publikováno v: BMC Nephrology, Vol 25, Iss 1, Pp 1-14 (2024)

Abstract Background Chronic kidney disease (CKD) affects almost 10% of the global populace including people living with HIV (PLWH). PLWH acquire CKD from both traditional and HIV-specific CKD risk factors. This study aimed to determine the prevalence

Externí odkaz: https://doaj.org/article/f8929682da624f0585b7c2a19d3b958f

Acceptability, barriers and facilitators of using dried blood spots-point-of-care testing for sickle cell disease in Africa: an implementation science protocol for a multinational qualitative study

Autor: Andre Pascal Kengne, Leon Tshilolo, Grace Ndeezi, Nicola Mulder, Moses Joloba, Victoria Nembaware, Nchangwi Syntia Munung, Vivian Paintsil, Emmanuel Peprah, Fred Stephen Sarfo, Deogratias Munube, Collen Masimirembwa, Ambroise Wonkam, Daniel Ansong, Kwaku Ohene-Frempong, Ezekiel Mupere, Sarah Kiguli, Julie Makani, Josephine Mgaya, Siana Nkya, Fred Semitala, Raphael Zozimus Sangeda, Emmanuel Balandya, Anazoeze Madu, Catherine Chunda-Liyoka, Yeya Dit Sadio Sarro, Daudi Jjingo, Obiageli Eunice Nnodu, Lulu Chirande, Boubacari Ali Touré, Aldiouma Guindo, Patience Kuona, Kevin Esoh, Mario Jonas, Maxwell Nwegbu, Upendo Masamu, Jack Morrice, Patrick Ohiani Moru, Valentina Ngo Bitoungui, Hans Ackerman, Alex Osei Akoto, Emmanuela Ambrose, Evans Amuzu, Samuel Asala, Biobele Brown, Mmbando Bruno, Daima Bukini, Pamela Gorejena, Abdul Aziz Hassan, Justin Hokororo, Jade Hotchkiss, Abdoul Malik Idris, Hezekiah Isa, Agnes Jonathan, Gwendoline Q. Kandawasvika, Daniel Kandonga, Ibrahima Keita, Sekou Kene, Frank Makundi, Janeth Manongi, Hamakwa Mantina, Jason Maro, Irene Kida Minja, Khuthala Mnika, Takudzwa Mtisi, Wilson Mupfururirwa, Ritah Mutagonda, Ruth Namazzi, Solomon Ofori-Aquah, Emmanuel Okocha, Fumni Olopade, Jesca Ondego, Chandré Oosterwyk-Liu, Nash Oyekanmi, Stella Paul, Cynthia Phiri, Paschal Ruggajo, Parker Ruhl, Ian Machingura Ruredzo, Pauline Sambo, Sawabati Shabani, Florence Urio, Robert Opoka

Publikováno v: BMJ Open, Vol 14, Iss 11 (2024)

Background Sickle cell disease (SCD) is a prevalent inherited blood disorder. Globally, approximately 515 000 babies are born with SCD annually, with 75% of these births occurring in Africa. Integrating newborn screening (NBS) for SCD into primary he

Externí odkaz: https://doaj.org/article/071fae27709947318206425d2fa31a68

Association between the MTNR1B, HHEX, SLC30A8, and TCF7L2 single nucleotide polymorphisms and cardiometabolic risk profile in a mixed ancestry South African population

Autor: Ndonwi Elvis Ngwa, Don Makwakiwe Matshazi, Glenda Mary Davison, Andre Pascal Kengne, Tandi Edith Matsha

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Abstract Single nucleotide polymorphisms of the TCF7L2, HHEX, SLC30A8, MTNR1B, SLC2A2 and GLIS3 genes are well established candidate genes for cardiometabolic diseases (CMDs) across different ethnic populations. We investigated their association with

Externí odkaz: https://doaj.org/article/b8a08ce94db04ed2aa636e45846495f4

Interdisciplinary perspectives on multimorbidity in Africa: Developing an expanded conceptual model.

Autor: Justin Dixon, Ben Morton, Misheck J Nkhata, Alan Silman, Ibrahim G Simiyu, Stephen A Spencer, Myrna Van Pinxteren, Christopher Bunn, Claire Calderwood, Clare I R Chandler, Edith Chikumbu, Amelia C Crampin, John R Hurst, Modou Jobe, Andre Pascal Kengne, Naomi S Levitt, Mosa Moshabela, Mayowa Owolabi, Nasheeta Peer, Nozgechi Phiri, Sally J Singh, Tsaone Tamuhla, Mandikudza Tembo, Nicki Tiffin, Eve Worrall, Nateiya M Yongolo, Gift T Banda, Fanuel Bickton, Abbi-Monique Mamani Bilungula, Edna Bosire, Marlen S Chawani, Beatrice Chinoko, Mphatso Chisala, Jonathan Chiwanda, Sarah Drew, Lindsay Farrant, Rashida A Ferrand, Mtisunge Gondwe, Celia L Gregson, Richard Harding, Dan Kajungu, Stephen Kasenda, Winceslaus Katagira, Duncan Kwaitana, Emily Mendenhall, Adwoa Bemah Boamah Mensah, Modai Mnenula, Lovemore Mupaza, Maud Mwakasungula, Wisdom Nakanga, Chiratidzo Ndhlovu, Kennedy Nkhoma, Owen Nkoka, Edwina Addo Opare-Lokko, Jacob Phulusa, Alison Price, Jamie Rylance, Charity Salima, Sangwani Salimu, Joachim Sturmberg, Elizabeth Vale, Felix Limbani

Publikováno v: PLOS Global Public Health, Vol 4, Iss 7, p e0003434 (2024)

Multimorbidity is an emerging challenge for health systems globally. It is commonly defined as the co-occurrence of two or more chronic conditions in one person, but its meaning remains a lively area of academic debate, and the utility of the concept

Externí odkaz: https://doaj.org/article/32bf2d97e2a74d06b14764f6364a7432

The prevalence of insufficient iodine intake in pregnancy in Africa: a systematic review and meta-analysis

Autor: Charles Bitamazire Businge, Hannibal Tafadzwa Musarurwa, Benjamin Longo-Mbenza, Andre Pascal Kengne

Publikováno v: Systematic Reviews, Vol 11, Iss 1, Pp 1-12 (2022)

Abstract Background Fortification of foodstuffs with iodine, mainly through iodization of salt, which commenced in several African countries after 1995 is the main method for mitigating iodine deficiency in Africa. We assessed the degree of iodine nu

Externí odkaz: https://doaj.org/article/610dc64ba9b44a748f3dd198ebd3ff56