Zobrazeno 1 - 10
of 235
pro vyhledávání: '"ANDRAS PERL"'
Publikováno v:
ACR Open Rheumatology, Vol 6, Iss 6, Pp 334-346 (2024)
Despite being some of the most anecdotally well‐known roads to pathogenesis, the mechanisms governing autoimmune rheumatic diseases are not yet fully understood. The overactivation of the cellular immune system and the characteristic development of
Externí odkaz:
https://doaj.org/article/610c5978ca8a40da89c398b807c20f0f
Autor:
Nick Huang, Thomas Winans, Brandon Wyman, Zachary Oaks, Tamas Faludi, Gourav Choudhary, Zhi-Wei Lai, Joshua Lewis, Miguel Beckford, Manuel Duarte, Daniel Krakko, Akshay Patel, Joy Park, Tiffany Caza, Mahsa Sadeghzadeh, Laurence Morel, Mark Haas, Frank Middleton, Katalin Banki, Andras Perl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-26 (2024)
Abstract Activation of the mechanistic target of rapamycin (mTOR) is a key metabolic checkpoint of pro-inflammatory T-cell development that contributes to the pathogenesis of autoimmune diseases, such as systemic lupus erythematosus (SLE), however, t
Externí odkaz:
https://doaj.org/article/e3357fd5b886440da3453dab516c3244
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/334d408f9804475cb4060554f7eb3200
Publikováno v:
Clinical Immunology Communications, Vol 2, Iss , Pp 54-56 (2022)
The 2019 Coronavirus disease (COVID-19) vaccine is a major weapon in the fight against the severe acute respiratory syndrome brought about by coronavirus 2 (SARS-CoV-2). The vaccine significantly reduces the risk and severity of infection by SARS-CoV
Externí odkaz:
https://doaj.org/article/6b7108ad04c44b299975225956a2c715
Autor:
Andras Perl, Laurence Morel
Publikováno v:
EBioMedicine, Vol 90, Iss , Pp 104520- (2023)
Externí odkaz:
https://doaj.org/article/2cbd41576add41128049491d3b453be2
Autor:
Russell C. Levack, Krista L. Newell, Berenice Cabrera-Martinez, Justin Cox, Andras Perl, Sheldon I. Bastacky, Gary M. Winslow
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
CD11c+T-bet+ B cells have been linked with different autoimmune diseases, but targeting these cells has been challenging. Here the authors use an adenosine 2A receptor agonist to deplete these B cells and to inhibit or reverse autoimmune symptoms and
Externí odkaz:
https://doaj.org/article/ad1d117384734ced8d0988ad19e62902
Autor:
ANDRAS PERL, Hajra Tily, Zhi-wei Lai, Julie Yu, Stephen V Faraone, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Maha Dawood, Ricardo Garcia, Lisa Francis, Paul E Phillips
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/0cef401f7fc543deb878c26431ce792f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/a854bc96ba534189b93735374461bfb9
Autor:
Joy S. Park, Andras Perl
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10749 (2023)
Endocytic recycling regulates the cell surface receptor composition of the plasma membrane. The surface expression levels of the T cell receptor (TCR), in concert with signal transducing co-receptors, regulate T cell responses, such as proliferation,
Externí odkaz:
https://doaj.org/article/499a0f5de96d45f282ca150498bc6e6f
Publikováno v:
Clinical Immunology Communications, Vol 1, Iss , Pp 1-3 (2021)
We describe a 64-year-old Caucasian female with a history of Raynaud's disease, hand arthritis, photosensitivity, Sjogren's syndrome and leukocytoclastic vasculitis who presented with progressively worsening fingertip necrosis that began three days a
Externí odkaz:
https://doaj.org/article/3b80059aa2db493d80fe2ab643ac2863