Close Encounters of the Third Domain: The Emerging Genomic View of Archaeal Diversity and Evolution

Autor: Anja Spang, Joran Martijn, Jimmy H. Saw, Anders E. Lind, Lionel Guy, Thijs J. G. Ettema

Publikováno v: Archaea, Vol 2013 (2013)

The Archaea represent the so-called Third Domain of life, which has evolved in parallel with the Bacteria and which is implicated to have played a pivotal role in the emergence of the eukaryotic domain of life. Recent progress in genomic sequencing t

Externí odkaz: https://doaj.org/article/a16f7c5421a94399ace1ddb3db109f9d

Novel TPR::ROS1 Fusion Gene Activates MAPK, PI3K and JAK/STAT Signaling in an Infant-type Pediatric Glioma

Autor: LILY DELAND, SIMON KEANE, THOMAS OLSSON BONTELL, HENRIK FAGMAN, HELENE SJÖGREN, ANDERS E. LIND, HELENA CARÉN, MAGNUS TISELL, JONAS A. NILSSON, KATARINA EJESKÄR, MAGNUS SABEL, FRIDA ABEL

BACKGROUND/AIM: Although fusion genes involving the proto-oncogene receptor tyrosine kinase ROS1 are rare in pediatric glioma, targeted therapies with small inhibitors are increasingly being approved for histology-agnostic fusion-positive solid tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76905c783246a995ac43a1144e0940b
http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-22033

Hikarchaeia demonstrate an intermediate stage in the methanogen-to-halophile transition

Autor: Anders E. Lind, Julian Vosseberg, Max Emil Schön, Thijs J. G. Ettema, Tom A. Williams, Joran Martijn, Anja Spang

Publikováno v: Nature Communications
Nature Communications 11 (2020) 1
Martijn, J, Schoen, M, Lind, A, Vosseberg, J, Williams, T, Spang, A & Ettema, T J G 2020, ' Hikarchaeia demonstrate an intermediate stage in the methanogen-to-halophile transition ', Nature Communications, vol. 11, 5490 (2020) . https://doi.org/10.1038/s41467-020-19200-2
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 11, 1. Nature Publishing Group
Nature Communications, 11(1)

Halobacteria (henceforth: Haloarchaea) are predominantly aerobic halophiles that are thought to have evolved from anaerobic methanogens. This remarkable transformation most likely involved an extensive influx of bacterial genes. Whether it entailed a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6d80aa5d34fad14de1289db1295a38
https://doi.org/10.1038/s41467-020-19200-2

Convergent Evolution of Hydrogenosomes from Mitochondria by Gene Transfer and Loss

Autor: Thijs J. G. Ettema, T. Martin Embley, William H Lewis, Kacper M Sendra, Anders E. Lind, Robert P. Hirt, Tom A. Williams, Genoveva F. Esteban, Henning Onsbring

Publikováno v: Molecular Biology and Evolution 37 (2020) 2
Molecular Biology and Evolution
Molecular Biology and Evolution, 37(2), 524-539
Lewis, W, Lind, A, Sendra, K M, Onsbring, H, Williams, T, Esteban, G, Hirt, R P, Ettema, T J G & Embley, T M 2019, ' Convergent evolution of hydrogenosomes from mitochondria by gene transfer and loss ', Molecular Biology and Evolution . https://doi.org/10.1093/molbev/msz239

Hydrogenosomes are H2-producing mitochondrial homologs found in some anaerobic microbial eukaryotes that provide a rare intracellular niche for H2-utilizing endosymbiotic archaea. Among ciliates, anaerobic and aerobic lineages are interspersed, demon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda88c09c02f7a74829aae7075c01a65
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-408104

Confident phylogenetic identification of uncultured prokaryotes through long read amplicon sequencing of the 16S-ITS-23S rRNA operon

Autor: Olga Vinnere Pettersson, Thijs J. G. Ettema, Ignas Bunikis, Anders E. Lind, Max Emil Schön, Ian Spiertz, Lina Juzokaite, Joran Martijn

Publikováno v: Environmental Microbiology
Environmental Microbiology 21 (2019) 7
Environmental Microbiology, 21(7), 2485-2498

Amplicon sequencing of the 16S rRNA gene is the predominant method to quantify microbial compositions and to discover novel lineages. However, traditional short amplicons often do not contain enough information to confidently resolve their phylogeny.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d3b25f7aa2c41ac385f1cc43701a93
https://pubmed.ncbi.nlm.nih.gov/31012228