Zobrazeno 1 - 10
of 76
pro vyhledávání: '"ANALGESIC ADJUVANT"'
Autor:
Arinze Duke George Nwosu, Leo C Chukwu, Okechukwu Onwuasoigwe, Sylvester O Nweze, Kenneth Nwadike
Publikováno v:
Indian Journal of Pain, Vol 37, Iss 2, Pp 65-73 (2023)
Conventional analgesics have traditionally been the mainstay of pain management, but unsatisfactory pain relief and troubling side effects have led to continuing search for more efficacious and safer remedies. Adjuvant analgesics are drugs with benef
Externí odkaz:
https://doaj.org/article/4ae705f352794121974052a581d99763
Autor:
Eiichi Kumamoto
Publikováno v:
Encyclopedia, Vol 2, Iss 4, Pp 1902-1934 (2022)
The action potential (AP) conduction in nerve fibers plays a crucial role in transmitting nociceptive information from the periphery to the cerebral cortex. Nerve AP conduction inhibition possibly results in analgesia. It is well-known that many anal
Externí odkaz:
https://doaj.org/article/3a80b61b1c434fd282a904d9f028a69b
Publikováno v:
Journal of Pain Research, Vol Volume 10, Pp 1801-1809 (2017)
J Ryan Scott,1 Afton L Hassett,1 Chad M Brummett,1 Richard E Harris,1,2 Daniel J Clauw,1,2 Steven E Harte1,2 1Chronic Pain and Fatigue Research Center, Department of Anesthesiology, 2Department of Internal Medicine, Division of Rheumatology, Universi
Externí odkaz:
https://doaj.org/article/f9edc44619b44ffab63ae156b3119efb
Autor:
Eiichi Kumamoto
Publikováno v:
Pharmaceuticals, Vol 13, Iss 4, p 62 (2020)
Nociceptive information is transmitted from the periphery to the cerebral cortex mainly by action potential (AP) conduction in nerve fibers and chemical transmission at synapses. Although this nociceptive transmission is largely inhibited at synapses
Externí odkaz:
https://doaj.org/article/3d6a0d1f2b424483b416d3ebeb42f4a5
Autor:
Felicity Y. Han, Andrew K. Whittaker, Steven M. Howdle, Andrew Naylor, Anjumn Shabir-Ahmed, Cheng Zhang, Maree T. Smith
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 264 (2018)
Pain is inadequately relieved by escalating doses of a strong opioid analgesic such as morphine in up to 25% of patients with cancer-related severe pain complicated by a neuropathic (nerve damage) component. Hence, there is an unmet medical need for
Externí odkaz:
https://doaj.org/article/642895c52bf94bb4b194afe7b11d3364
Akademický článek
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Autor:
Han, Felicity, Whittaker, Andrew, Howdle, Steven, Naylor, Andrew, Shabir-Ahmed, Anjumn, Zhang, Cheng, Smith, Maree
Pain is inadequately relieved by escalating doses of a strong opioid analgesic such as morphine in up to 25% of patients with cancer-related severe pain complicated by a neuropathic (nerve damage) component. Hence, there is an unmet medical need for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::44797dd366d7fbcf242750228e7a8d22
Akademický článek
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Autor:
Funai, Yusuke, Funao, Tomoharu, Ikenaga, Kazutake, Takahashi, Ryota, Hase, Ichiro, Nishikawa, Kiyonobu
Publikováno v:
Osaka City Medical Journal. 60(1):11-19
Background : Tricyclic antidepressants (TCAs) are known to prolong QTc interval. However, little is known about the QTc lengthening effect of TCAs at analgesic dosages and the predictive factors for abnormal QTc prolongation. / Methods : We conducted
Akademický článek
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