Zobrazeno 1 - 10
of 7 523
pro vyhledávání: '"AMYLOID BETA-PEPTIDE"'
Autor:
Rethinam Senthil
Publikováno v:
Toxicology Reports, Vol 13, Iss , Pp 101778- (2024)
The development and characterization of anticancer complex drugs (ACD), specifically Amyloid Beta Peptide (ABP) - Ruthenium III (Ru III) - nivolumab (NB), were explored through analytical techniques. Fourier-transform infrared (FTIR) spectroscopy dem
Externí odkaz:
https://doaj.org/article/001a3e97b0ab409a93afbcd62bc3eec5
Akademický článek
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Akademický článek
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Autor:
Madhu S. Budamagunta, Hidetoshi Mori, Joshua Silk, Ryan R. Slez, Balázs Bognár, Ulises Ruiz Mendiola, Tamás Kálai, Izumi Maezawa, John C. Voss
Publikováno v:
Antioxidants, Vol 13, Iss 11, p 1411 (2024)
The disorder and heterogeneity of low-molecular-weight amyloid-beta oligomers (AβOs) underlie their participation in multiple modes of cellular dysfunction associated with the etiology of Alzheimer’s disease (AD). The lack of specified conformatio
Externí odkaz:
https://doaj.org/article/475cc58fa1364a01b0428157530bf5ee
Autor:
Tsu-Kung Lin, Chi-Ren Huang, Kai-Jung Lin, Yi-Heng Hsieh, Shang-Der Chen, Yi-Chun Lin, A-Ching Chao, Ding-I Yang
Publikováno v:
Antioxidants, Vol 13, Iss 11, p 1378 (2024)
The major pathological characteristics of Alzheimer’s disease (AD) include senile plaques and neurofibrillary tangles (NFTs), which are mainly composed of aggregated amyloid-beta (Aβ) peptide and hyperphosphorylated tau protein, respectively. The
Externí odkaz:
https://doaj.org/article/3ec10bfd3daa46cd8efc27baa4f42ee8
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1443 (2024)
Peptides possess a number of pharmacologically desirable properties, including greater chemical diversity than other biomolecule classes and the ability to selectively bind to specific targets with high potency, as well as biocompatibility, biodegrad
Externí odkaz:
https://doaj.org/article/e40427d75b2e4ecb87a79098cdd7bf56
Autor:
Ryder Davidson, Reese I. Krider, Philip Borsellino, Keith Noorda, George Alhwayek, Thomas A. Vida
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 8816-8839 (2023)
Neuroinflammation, a core pathological feature observed in several neurodegenerative diseases, including Alzheimer’s disease (AD), is rapidly gaining attention as a target in understanding the molecular underpinnings of these disorders. Glial cells
Externí odkaz:
https://doaj.org/article/41beca0a9bb64f129382349375589a27
Autor:
Björn Johansson, Sho Oasa, Aida Muntsant Soria, Ann Tiiman, Linda Söderberg, Ebba Amandius, Christer Möller, Lars Lannfelt, Lars Terenius, Lydia Giménez-Llort, Vladana Vukojević
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Background Standard neuropathologic analysis of Alzheimer’s brain relies on traditional fluorescence microscopy, which suffers from limited spatial resolution due to light diffraction. As a result, it fails to reveal intricate details of a
Externí odkaz:
https://doaj.org/article/dee0db3a60734c11941bb0c8d4633267
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 17, Iss 2, Pp 75-83 (2023)
Alzheimer's disease (AD) is the most common neurodegenerative disease and cause of dementia. It is associated with progressive cognitive decline due to the development of cortical and hippocampal atrophy. We reviewed key factors in AD pathogenesis
Externí odkaz:
https://doaj.org/article/db2027e887b044c2a9e8f8382f6f22fa
Autor:
Yu-Jung Lin, Chih-Yang Huang, Bruce Chi-Kang Tsai, Kannan Ashok Kumar, Dennis Jine-Yuan Hsieh, Ping-Ling Chiu, Yung-Ming Chang, Tsung-Jung Ho, Wei-Wen Kuo, Da-Tong Ju
Publikováno v:
Journal of Functional Foods, Vol 110, Iss , Pp 105874- (2023)
Alpha-synuclein (α-syn) and amyloid-beta peptide (Aβ) accumulation cause neurodegenerative diseases. The accumulation of neurotoxins, like Aβ, tau, and α-syn is related to aging therefore studying aging mediated neurodegenerative disease is impor
Externí odkaz:
https://doaj.org/article/66c717f01e644688b4078fda7f84fa97