Zobrazeno 1 - 10
of 258
pro vyhledávání: '"AMPK-mTOR pathway"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionDepression is a common psychological disorder, accompanied by a disturbance of the gut microbiota and its metabolites. Recently, microbiota-derived tryptophan metabolism and AMPK/mTOR pathway were found to be strongly linked to the develo
Externí odkaz:
https://doaj.org/article/f679474a78a0489992c4674bec0ca2d3
Autor:
Yue Yin, Chunyan Yan, Rui Zhang, Yuliang Wang, Yang Song, Shujuan Hu, Xin Zhao, Ruofan Liu, Minghao Guo, Yaxuan Wang, Xin Cai, Dexiu Wang
Publikováno v:
Journal of Functional Foods, Vol 116, Iss , Pp 106168- (2024)
Vascular dementia (VD), a chronic syndrome of acquired intellectual impairment resulting from cerebrovascular diseases, is closely linked to neuronal autophagy and apoptosis. As a standardized extract from Ginkgo biloba L. leaves, EGb761 is widely ap
Externí odkaz:
https://doaj.org/article/057420e74c4a45d38e7792df68f34fea
Autor:
Rong Li, Wenjie Duan, Tingle Feng, Chenyang Gu, Qiankun Zhang, Jun Long, Shiying Huang, Lukui Chen
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-16 (2023)
Abstract Background Neural stem cell-derived extracellular vesicles (NSC-EVs) mediated endogenous neurogenesis determines a crucial impact on spontaneous recovery after stroke. Here, we checked the influence of Lycium barbarum polysaccharide (LBP) on
Externí odkaz:
https://doaj.org/article/cee57a5c6d5640b0a9ee06e904c2fa2b
Autor:
Yan Li, Yongying Zhou, Daoquan Liu, Zhen Wang, Jizhang Qiu, Junchao Zhang, Ping Chen, Guang Zeng, Yuming Guo, Xinghuan Wang, Michael E. DiSanto, Xinhua Zhang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-29 (2023)
Abstract Background Benign prostatic hyperplasia (BPH) is a common disease in elderly men, mainly resulted from an imbalance between cell proliferation and death. Glutathione peroxidase 3 (GPX3) was one of the differentially expressed genes in BPH id
Externí odkaz:
https://doaj.org/article/1b5c10b6dae647a39ffa2e0ef2324734
Publikováno v:
Poultry Science, Vol 103, Iss 3, Pp 103442- (2024)
ABSTRACT: Intermittent cold stimulation (ICS) enhances broilers’ resistance to cold stress. Nonetheless, further research is needed to investigate the underlying mechanisms that enhance cold stress resistance. A total of 160 one-day-old male Ross 3
Externí odkaz:
https://doaj.org/article/0b9164bd878745d2a989a53a4c682f71
Autor:
Shengyuan Wang, Bengang Chen, Minghao Yuan, Shu Liu, Haixia Fan, Xu Yang, Qian Zou, Yinshuang Pu, Zhiyou Cai
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Age-related cognitive impairment represents a significant health concern, with the understanding of its underlying mechanisms and potential interventions being of paramount importance. This study aimed to investigate the effects of hyperbaric oxygen
Externí odkaz:
https://doaj.org/article/bf187b8f0a6b4262b1b98235dbe9815c
Publikováno v:
Animal Nutrition, Vol 13, Iss , Pp 1-8 (2023)
Since starch digestion in the small intestine provides more energy than digestion in the rumen of ruminants, reducing dietary rumen degradable starch (RDS) content is beneficial for improving energy utilization of starch in ruminants. The present stu
Externí odkaz:
https://doaj.org/article/167f3637327d42ad9e2cf87885cee019
Publikováno v:
Gynecological Endocrinology, Vol 39, Iss 1 (2023)
Objective: Polycystic ovarian syndrome (PCOS) is a prevalent gynecologic disorder, often associated with abnormal follicular development. Cangfu Daotan decoction (CFD) is a traditional Chinese medicine formula that is effective in alleviating PCOS cl
Externí odkaz:
https://doaj.org/article/82dab9d9efc1414c8936fddea2eb4f01
Publikováno v:
PeerJ, Vol 11, p e16517 (2023)
Objective The objective of this study was to investigate the effects and mechanisms of adipose-derived stem cell-derived exosome (ADSCs-Exo) in treating premature ovarian failure (POF). Methods We constructed a POF mouse model through intraperitoneal
Externí odkaz:
https://doaj.org/article/765d0a53826a439eaaa034286c6aafa9
Autor:
Chen Chen, Tao Zhu, Lifen Gong, Zhe Hu, Hao Wei, Jianchen Fan, Donghui Lin, Xiaojun Wang, Junyu Xu, Xinyan Dong, Yifan Wang, Ningxiao Xia, Linghui Zeng, Peifang Jiang, Yicheng Xie
Publikováno v:
Neurobiology of Disease, Vol 186, Iss , Pp 106273- (2023)
Epilepsy is one of the most common neurological disorders. Neuroinflammation involving the activation of microglia and astrocytes constitutes an important and common mechanism in epileptogenesis. Transient receptor potential melastatin 2 (TRPM2) is a
Externí odkaz:
https://doaj.org/article/98754b13d1ac4fd9bea6deb83c1bc203