AMPA receptor auxiliary subunits emerged during early vertebrate evolution by neo/subfunctionalization of unrelated proteins

Autor: David Ramos-Vicente, Àlex Bayés

Publikováno v: Open Biology, Vol 10, Iss 10 (2020)

In mammalian synapses, the function of ionotropic glutamate receptors is critically modulated by auxiliary subunits. Most of these specifically regulate the synaptic localization and electrophysiological properties of AMPA-type glutamate receptors (A

Externí odkaz: https://doaj.org/article/dd057046ed6a4161bfe6f235b07b0c6a

Metazoan evolution and diversity of glutamate receptors and their auxiliary subunits

Autor: Ramos-Vicente, D, Grant, SGN, Bayes, A

Publikováno v: NEUROPHARMACOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Glutamate is the major excitatory neurotransmitter in vertebrate and invertebrate nervous systems. Proteins involved in glutamatergic neurotransmission, and chiefly glutamate receptors and their auxiliary subunits, play key roles in nervous system fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::bd33af46065e005ad2f21ba5add7d5b8
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4390

Metazoan evolution and diversity of glutamate receptors and their auxiliary subunits.

Autor: Ramos-Vicente D; Molecular Physiology of the Synapse Laboratory, Biomedical Research Institute Sant Pau, Barcelona, Spain; Universitat Autònoma de Barcelona, Barcelona, Spain., Grant SG; Centre for Clinical Brain Sciences, Chancellor's Building, Edinburgh BioQuarter, University of Edinburgh, Edinburgh, EH16 4SB, UK; Simons Initiative for the Developing Brain (SIDB), Centre for Discovery Brain Sciences, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh, EH8 9XD, UK., Bayés À; Molecular Physiology of the Synapse Laboratory, Biomedical Research Institute Sant Pau, Barcelona, Spain; Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address: abayesp@santpau.cat.

Publikováno v: Neuropharmacology [Neuropharmacology] 2021 Sep 01; Vol. 195, pp. 108640. Date of Electronic Publication: 2021 Jun 08.