Zobrazeno 1 - 10
of 1 225
pro vyhledávání: '"AMP-activated protein kinase(AMPK)"'
Autor:
Mariola Olkowicz, Agnieszka Karas, Piotr Berkowicz, Patrycja Kaczara, Agnieszka Jasztal, Zuzanna Kurylowicz, Filip Fedak, Hernando Rosales-Solano, Kanchan Sinha Roy, Agnieszka Kij, Elzbieta Buczek, Janusz Pawliszyn, Stefan Chlopicki
Publikováno v:
Pharmacological Research, Vol 210, Iss , Pp 107478- (2024)
Mitochondrial dysfunction and 12-lipoxygenase (ALOX12)-derived 12(S)-HETE production have been associated with vascular inflammation and the pathogenesis of atherosclerosis. However, the role of ALOX12 in regulating vascular energy metabolism in vasc
Externí odkaz:
https://doaj.org/article/8ca22da45ba24b6e961c7c33ebd74e00
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Dysregulation in histone acetylation, a significant epigenetic alteration closely associated with major pathologies including cancer, promotes tumorigenesis, inactivating tumor-suppressor genes and activating oncogenic pathways. A
Externí odkaz:
https://doaj.org/article/9ad56304106049e5925bc82ddd268493
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2615 (2024)
Background/Objectives: The severity of acute lung injury is significantly impacted by age and sex in patients with hemorrhagic shock. AMP-activated protein kinase (AMPK) is a crucial regulator of energy metabolism but its activity declines with aging
Externí odkaz:
https://doaj.org/article/5151278ed1b94caa9279c977236345c9
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 3739-3740 (2024)
Lian W, Chen W. Drug Des Devel Ther. 2020;14:3385–3391. We, the Editor and Publisher of the journal Drug Design, Development and Therapy have retracted the published article. Following publication of the article, concerns were raised about the dupl
Externí odkaz:
https://doaj.org/article/494ede36e0b84e9cad42f011a2037ce5
Autor:
Xu Zhang
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/e8a4c1297f084fe4b6fea658230a5b66
Publikováno v:
Shipin Kexue, Vol 44, Iss 15, Pp 129-136 (2023)
Objective: To investigate the effect of hawthorn procyanidins (HPC) on lipid metabolism and its mechanism by regulating the AMP-activated protein kinase/sterol regulatory element binding protein-1c (AMPK/SREBP-1c) signaling pathway. Methods: Sixty ra
Externí odkaz:
https://doaj.org/article/cecc4ce4a91141a6b514a7a2fc722658
Autor:
Steffen H. Raun, Mona S. Ali, Xiuqing Han, Carlos Henríquez‐Olguín, T.C. Phung Pham, Roberto Meneses‐Valdés, Jonas R. Knudsen, Anna C.H. Willemsen, Steen Larsen, Thomas E. Jensen, Ramon Langen, Lykke Sylow
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1631-1647 (2023)
Abstract Background Metabolic dysfunction and cachexia are associated with poor cancer prognosis. With no pharmacological treatments, it is crucial to define the molecular mechanisms causing cancer‐induced metabolic dysfunction and cachexia. Adenos
Externí odkaz:
https://doaj.org/article/7e761cbfe9a2416998776cb54140a53c
Autor:
Jian Zhang, Hui Gong, Tingting Zhao, Weitong Xu, Honghan Chen, Tiepeng Li, Yu Yang, Ming Yang, Ning Huang, Chuhui Gong, Fangfang Wang, Cuiying Zhang, Jin Liu, Hengyi Xiao
Publikováno v:
MedComm, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract Senescence‐associated microRNAs (SA‐miRNAs) are important molecules for aging regulation. While many aging‐promoting SA‐miRNAs have been identified, confirmed aging‐suppressive SA‐miRNAs are rare, that impeded our full understand
Externí odkaz:
https://doaj.org/article/d69463e9705548748608c83cb797c9a5
Autor:
Safaa I. Khater, Maram Shalabi, Buthainah B. Alammash, Alaa I. Alrais, Doaa Al-ahmadi, Leena S. Alqahtani, Tarek Khamis, Sahar Abdelaziz, Khalifa Aldawy
Publikováno v:
Journal of Advanced Veterinary and Animal Research, Vol 10, Iss 2, Pp 308-320 (2023)
Phytoestrogens are non-steroid polyphenolic materials present in 300 plants. Regarding their structural similarities to estradiol, phytoestrogens attach to estrogen receptors and display anti-or pro-estrogenic activities. This review explored phytoes
Externí odkaz:
https://doaj.org/article/899a753aaf844801959989c07e00b4fd
Autor:
Seyedeh Mona Mousavi Esfahani, Parastoo Tarighi, Kosar Dianat, Tabarek Mahdi Ashour, Negar Mottaghi-Dastjerdi, Mehdi Aghsami, Mahsa Sabernavaei, Hamed Montazeri
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Paliurus spina-christi Mill. (PSC) fruit is frequently used in the treatment of diabetes mellitus in Mediterranean regions. Here, we investigated the effects of various PSC fruit extracts (PSC-FEs) on glucose consumption and some
Externí odkaz:
https://doaj.org/article/f2b46d1c66b94ff29dfb40c679a8d9d5