Zobrazeno 1 - 10
of 2 397
pro vyhledávání: '"AMIT SHARMA"'
Autor:
Yulu Wang, Jiading Qin, Amit Sharma, Tikam Chand Dakal, Jieyu Wang, Tiantian Pan, Ravi Bhushan, Peng Chen, Maria F. Setiawan, Ingo G.H. Schmidt-wolf, Fei Li
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract RGS (Regulator of G protein signaling) proteins have long captured the fascination of researchers due to their intricate involvement across a wide array of signaling pathways within cellular systems. Their diverse and nuanced functions have
Externí odkaz:
https://doaj.org/article/aeae2af397144ee6810256fe02c2658a
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 3, Pp 11-20 (2024)
Background: Bael is well-known for its antibacterial properties. Aqueous fruit extracts have also been shown to have hepatoprotective properties; the nephroprotective and hepatoprotective properties of Ethanolic extracts have not yet been tested. Obj
Externí odkaz:
https://doaj.org/article/1a9d2e3465304a30a09522101e7f4494
Autor:
Chunxia Zhao, Yulu Wang, Huan Wang, Amit Sharma, Yun Wu, Ingo G. H. Schmidt-Wolf, Zifeng Wang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Background Acute myeloid leukemia, constituting a majority of leukemias, grapples with a 24% 5-year survival rate. Recent strides in research have unveiled fresh targets for drug therapies. LIM-only, a pivotal transcription factor within LIM
Externí odkaz:
https://doaj.org/article/e63cf600083a45daa69c4e3f99bf7278
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Undeniably, cancer immunotherapies have expanded the spectrum of cancer treatment, however, some patients do not respond to immunotherapies. This scenario is no different for lung cancer, whose two main types, non-small cell lung cancer (NSC
Externí odkaz:
https://doaj.org/article/69bfd3fa7c6a4ad7981fd82e32a8349f
Autor:
Jingjing Pu, Ting Liu, Xuzhen Wang, Amit Sharma, Ingo G. H. Schmidt-Wolf, Liping Jiang, Jian Hou
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-19 (2024)
Abstract Histone deacetylase inhibitors (HDACis) are a significant category of pharmaceuticals that have developed in the past two decades to treat multiple myeloma. Four drugs in this category have received approval from the U.S. Food and Drug Admin
Externí odkaz:
https://doaj.org/article/b434a3dee12c430db83ac99420578c56
Autor:
Gaurav Kumar, Sanjeev Gupta, Jaspreet Kaur, Shweta Pasi, Rajendra Baharia, Ajeet Kumar Mohanty, Pawan Goel, Amit Sharma, Manju Rahi
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Achieving effective control and elimination of malaria in endemic regions necessitates a comprehensive understanding of local mosquito species responsible for malaria transmission and their susceptibility to insecticides. Methods
Externí odkaz:
https://doaj.org/article/02fc22d2edfc4d419bf503f612c58954
Autor:
Siddhartha Mishra, Nipun Malhotra, Benoît Laleu, Soumyananda Chakraborti, Manickam Yogavel, Amit Sharma
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110049- (2024)
Summary: The prolyl-tRNA synthetase (PRS) is an essential enzyme for protein translation and a validated target against malaria parasite. We describe five ATP mimetics (L95, L96, L97, L35, and L36) against PRS, exhibiting enhanced thermal stabilities
Externí odkaz:
https://doaj.org/article/af630037dd0645c6b8cbafbe9a69bcdc
Autor:
Kuldeep Singh, Piyush Singh, Anupkumar R Anvikar, Chander Prakash Yadav, Amit Sharma, Manju Rahi, Atul Goel, Sanjeev Kumar Gupta, S P Singh, Rinku Sharma, Tanu Jain, Vani H C, Shrinivasa B M, Richa Singhal, Sujith Nath N, Praveen Kumar Tripathi, Alex Eapen, D P Sinha, Waseem Akram Malla, Pallika Singh, C S Aggarwal, Vinod P Choudhary
Publikováno v:
BMJ Open, Vol 14, Iss 7 (2024)
Introduction India’s contribution to the malaria burden was highest in South-East Asia Region in 2021, accounting for 79% of the estimated malaria cases and 83% of malaria-related deaths. Intensified Malaria Control Programme supported by Global Fu
Externí odkaz:
https://doaj.org/article/f4dc65d709ef4728af973952e9b349e4
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract A firm link between endoplasmic reticulum (ER) stress and tumors has been wildly reported. Endoplasmic reticulum oxidoreductase 1 alpha (ERO1α), an ER-resident thiol oxidoreductase, is confirmed to be highly upregulated in various cancer ty
Externí odkaz:
https://doaj.org/article/500a17bba7f641ce9780392d3808f1fd
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 1, Pp 100-107 (2024)
Background: The Cinnamomum impressinervium (CI) Meisn. Tree, which belongs to the Lauraceae family and is endemic to India, is also called Assameses or Tejiya. Numerous pharmacological properties of this plant, including anti-tumor, anti-inflammatory
Externí odkaz:
https://doaj.org/article/60d7724e7c1a4465961da8e833ecc81d