TRIM35 triggers cardiac remodeling by regulating SLC7A5-mediated amino acid transport and mTORC1 activation in fibroblasts.

Autor: Yang, Boshen¹ (AUTHOR), Wang, Zhixiang¹ (AUTHOR), Niu, Kaifan¹ (AUTHOR), Li, Taixi¹ (AUTHOR), Tong, Tingting² (AUTHOR), Li, Suiji³ (AUTHOR), Su, Liuhang³ (AUTHOR), Wang, Yan³ (AUTHOR), Shen, Chengxing¹ (AUTHOR) shencx@sjtu.edu.cn, Jin, Xian¹ (AUTHOR) jinxianian@126.com, Song, Juan³ (AUTHOR) songjuan_ok@163.com, Lu, Xia¹ (AUTHOR) xialu0292@163.com

Publikováno v: Cell Communication & Signaling. 9/20/2024, Vol. 22 Issue 1, p1-22. 22p.

Mammalian Amino Acid Transport : Mechanism and Control. [elektronicky zdroj]

Autor: Häussinger, D.

Externí odkaz: Kolekce e-knih KNAV (Registrovani uzivatele: plny text online 5 minut, dalsi pristup na vyzadani. Registered users: full text online 5 minutes, further access on request.)

SNF2L maintains glutathione homeostasis by initiating SLC7A11 transcription through chromatin remodeling.

Autor: Zhang J; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China., Gao Z; Department of Urology, The Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China., Yang Y; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China., Li Z; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China., Wu B; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China., Fan C; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China., Zheng Y; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China., Yang R; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China., Zhang F; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China., Lin X; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China., Zheng D; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China. zheng.daoshan@fjmu.edu.cn.

Publikováno v: Cell death & disease [Cell Death Dis] 2024 Nov 12; Vol. 15 (11), pp. 820. Date of Electronic Publication: 2024 Nov 12.

TRIM35 triggers cardiac remodeling by regulating SLC7A5-mediated amino acid transport and mTORC1 activation in fibroblasts

Autor: Boshen Yang, Zhixiang Wang, Kaifan Niu, Taixi Li, Tingting Tong, Suiji Li, Liuhang Su, Yan Wang, Chengxing Shen, Xian Jin, Juan Song, Xia Lu

Publikováno v: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)

Abstract Background Cardiac maladaptive remodeling is one of the leading causes of heart failure with highly complicated pathogeneses. The E3 ligase tripartite motif containing 35 (TRIM35) has been identified as a crucial regulator governing cellular

Externí odkaz: https://doaj.org/article/f114b1523ff0406c92b20114a03f63e0

Asparagine transport through SLC1A5/ASCT2 and SLC38A5/SNAT5 is essential for BCP-ALL cell survival and a potential therapeutic target.

Autor: Taurino G; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy., Dander E; Tettamanti Center, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Chiu M; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy., Pozzi G; Laboratory of Human Anatomy, Department of Medicine and Surgery, University of Parma, Parma, Italy., Maccari C; Laboratory of Industrial Toxicology, Department of Medicine and Surgery, University of Parma, Parma, Italy., Starace R; Tettamanti Center, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Silvestri D; Tettamanti Center, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Griffini E; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy., Bianchi MG; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy.; MRH-Microbiome Research Hub, Parco Area Delle Scienze 11/A, University of Parma, Parma, Italy., Carubbi C; Laboratory of Human Anatomy, Department of Medicine and Surgery, University of Parma, Parma, Italy., Andreoli R; Laboratory of Industrial Toxicology, Department of Medicine and Surgery, University of Parma, Parma, Italy.; CERT-Center of Excellence for Toxicological Research, University of Parma, Parma, Italy., Mirandola P; Laboratory of Human Anatomy, Department of Medicine and Surgery, University of Parma, Parma, Italy., Valsecchi MG; Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Rizzari C; Department of Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., D'Amico G; Tettamanti Center, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Bussolati O; Laboratory of General Pathology, Department of Medicine and Surgery, University of Parma, Parma, Italy.; MRH-Microbiome Research Hub, Parco Area Delle Scienze 11/A, University of Parma, Parma, Italy.

Publikováno v: British journal of haematology [Br J Haematol] 2024 Jul; Vol. 205 (1), pp. 175-188. Date of Electronic Publication: 2024 May 13.