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Specific involvement of tyrosine 764 of human granulocyte colony- stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes

Autor: JP de Koning, AM Schelen, F Dong, C van Buitenen, BM Burgering, JL Bos, B Lowenberg, IP Touw

Publikováno v: Blood. 87:132-140

Signal transduction from the granulocyte colony-stimulating factor receptor (G-CSF-R) occurs via multiple pathways, one of which involves activation of p21Ras and mitogen-activated protein kinase. The SH2 domain-containing proteins Shc and GRB2 have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78a126d07fc03afb9c52a782b825e4c2
https://doi.org/10.1182/blood.v87.1.132.bloodjournal871132

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Proliferation signaling and activation of Shc, p21Ras, and Myc via tyrosine 764 of human granulocyte colony-stimulating factor receptor

Autor: Jp, Koning, Aa, Soede-Bobok, Am, Schelen, Smith L, van Leeuwen D, VALERIA SANTINI, Bm, Burgering, Jl, Bos, Lowenberg B, Ip, Touw

Publikováno v: Europe PubMed Central

The membrane-distal region of the cytoplasmic domain of human granulocyte colony-stimulating factor receptor (G-CSF-R) contains four conserved tyrosine residues: Y704, Y729, Y744, and Y764. Three of these (Y729, Y744, and Y764) are located in the C-t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::03639949ad0e4affd0ea91e1e78222d5
https://pubmed.ncbi.nlm.nih.gov/9490675

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