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Plasma p-tau217 in Alzheimer's disease: Lumipulse and ALZpath SIMOA head-to-head comparison.

Autor: Pilotto A; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia 25123, Italy.; Department of continuity of care and frailty, Neurology Unit, ASST Spedali Civili Hospital, Brescia 25123, Italy.; Neurobiorepository and Laboratory of advanced biological markers, University of Brescia and ASST Spedali Civili Hospital, Brescia 25123, Italy., Quaresima V; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia 25123, Italy.; Department of continuity of care and frailty, Neurology Unit, ASST Spedali Civili Hospital, Brescia 25123, Italy.; Neurobiorepository and Laboratory of advanced biological markers, University of Brescia and ASST Spedali Civili Hospital, Brescia 25123, Italy.; Residency Program in Clinical Pathology and Clinical Biochemistry, Department of Molecular and Translational Medicine, University of Brescia, Brescia 25123, Italy.; Department of Clinical Laboratory, ASST Spedali Civili Hospital, Brescia 25123, Italy., Trasciatti C; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia 25123, Italy.; Department of continuity of care and frailty, Neurology Unit, ASST Spedali Civili Hospital, Brescia 25123, Italy.; Neurobiorepository and Laboratory of advanced biological markers, University of Brescia and ASST Spedali Civili Hospital, Brescia 25123, Italy.; Residency Program in Clinical Pathology and Clinical Biochemistry, Department of Molecular and Translational Medicine, University of Brescia, Brescia 25123, Italy., Tolassi C; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia 25123, Italy.; Department of continuity of care and frailty, Neurology Unit, ASST Spedali Civili Hospital, Brescia 25123, Italy.; Neurobiorepository and Laboratory of advanced biological markers, University of Brescia and ASST Spedali Civili Hospital, Brescia 25123, Italy.; Residency Program in Clinical Pathology and Clinical Biochemistry, Department of Molecular and Translational Medicine, University of Brescia, Brescia 25123, Italy., Bertoli D; Department of Clinical Laboratory, ASST Spedali Civili Hospital, Brescia 25123, Italy., Mordenti C; Department of Clinical Laboratory, ASST Spedali Civili Hospital, Brescia 25123, Italy., Galli A; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia 25123, Italy.; Department of continuity of care and frailty, Neurology Unit, ASST Spedali Civili Hospital, Brescia 25123, Italy., Rizzardi A; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia 25123, Italy.; Department of continuity of care and frailty, Neurology Unit, ASST Spedali Civili Hospital, Brescia 25123, Italy., Caratozzolo S; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia 25123, Italy.; Department of continuity of care and frailty, Neurology Unit, ASST Spedali Civili Hospital, Brescia 25123, Italy., Zancanaro A; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia 25123, Italy.; Department of continuity of care and frailty, Neurology Unit, ASST Spedali Civili Hospital, Brescia 25123, Italy., Contador J; Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona 08005, Spain.; Department of Neurology, Hospital del Mar Research Institute, Barcelona 08005, Spain.; Cognitive Decline Unit, Department of Neurology, Hospital del Mar, Barcelona 08005, Spain., Hansson O; Department of Clinical Sciences, Clinical Memory Research Unit, Malmö 205 02, Sweden.; Memory Clinic, Skåne University Hospital, Malmö 205 02, Sweden.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Malmö 205 02, Sweden., Palmqvist S; Department of Clinical Sciences, Clinical Memory Research Unit, Malmö 205 02, Sweden.; Memory Clinic, Skåne University Hospital, Malmö 205 02, Sweden.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Malmö 205 02, Sweden., De Santis G; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg 405 30, Sweden., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg 405 30, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal 431 30, Sweden.; Dementia Research Center, Institute of Neurology, University College London, London WC1E 6BT, UK.; UK Dementia Research Institute, University College London, London WC1E 6BT, UK.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53707, USA., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg 405 30, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris 75013, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei 230001, P.R. China., Brugnoni D; Department of Clinical Laboratory, ASST Spedali Civili Hospital, Brescia 25123, Italy., Suárez-Calvet M; Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona 08005, Spain.; Department of Neurology, Hospital del Mar Research Institute, Barcelona 08005, Spain.; Cognitive Decline Unit, Department of Neurology, Hospital del Mar, Barcelona 08005, Spain., Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg 405 30, Sweden.; Banner Sun Health Research Institute, Sun City, AZ 85351, USA.; Banner Alzheimer's Institute, Phoenix, AZ 85006, USA.; Brain Health Center, University of Brescia, Brescia 25123, Italy., Padovani A; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia 25123, Italy.; Department of continuity of care and frailty, Neurology Unit, ASST Spedali Civili Hospital, Brescia 25123, Italy.; Neurobiorepository and Laboratory of advanced biological markers, University of Brescia and ASST Spedali Civili Hospital, Brescia 25123, Italy.; Brain Health Center, University of Brescia, Brescia 25123, Italy.

Publikováno v: Brain : a journal of neurology [Brain] 2024 Dec 16. Date of Electronic Publication: 2024 Dec 16.

ALZpath Proprietary pTau217 Antibody Named to TIME'S List of the Best Inventions of 2024

Autor: PR Newswire

Publikováno v: PR Newswire US. 10/30/2024.

Diagnostic accuracy of the plasma ALZpath pTau217 immunoassay to identify Alzheimer's disease pathology.

Autor: Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; King's College London, Institute of Psychiatry, Psychology and Neuroscience Maurice Wohl Institute Clinical Neuroscience Institute London UK.; NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia at South London and Maudsley NHS Foundation London UK.; Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway., Brum WS; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil., Di Molfetta G; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Benedet AL; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Arslan B; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Jonatis E; Wisconsin Alzheimer's Institute, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA.; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA.; Department of Medicine, Division of Geriatrics and Gerontology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA., Langhough RE; Wisconsin Alzheimer's Institute, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA.; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA.; Department of Medicine, Division of Geriatrics and Gerontology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA., Cody K; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA., Wilson R; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA.; Department of Medicine, Division of Geriatrics and Gerontology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA., Carlsson CM; Wisconsin Alzheimer's Institute, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA.; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA.; Department of Medicine, Division of Geriatrics and Gerontology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA.; Geriatric Research Education and Clinical Center of the Wm. S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA., Vanmechelen E; ADx NeuroSciences, Technologiepark 94, Ghent, Belgium., Montoliu-Gaya L; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Lantero-Rodriguez J; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Rahmouni N; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Tissot C; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Stevenson J; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Servaes S; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Therriault J; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Pascoal T; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Lleó A; Department of Neurology, Institut d'Investigacions Biomèdiques Sant Pau - Hospital de Sant Pau, Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Barcelona, Catalunya.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain., Alcolea D; Department of Neurology, Institut d'Investigacions Biomèdiques Sant Pau - Hospital de Sant Pau, Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Barcelona, Catalunya.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain., Fortea J; Department of Neurology, Institut d'Investigacions Biomèdiques Sant Pau - Hospital de Sant Pau, Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Barcelona, Catalunya.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain., Rosa-Neto P; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Johnson S; Wisconsin Alzheimer's Institute, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA.; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA., Jeromin A; ALZpath. Inc, Carlsbad, CA 92008, USA., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Jul 12. Date of Electronic Publication: 2023 Jul 12.

ALZpath Dx: A novel accessible, validated, and scalable phosphorylated‐tau 217 (pTau217) assay in blood.

Autor: Portbury, Stuart D, Chaby, Lauren, Jeromin, Andreas

Publikováno v: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2023 Supplement 15, Vol. 19, p1-1, 1p