Zobrazeno 1 - 10
of 4 086
pro vyhledávání: '"ALZHEIMER ́S DISEASE"'
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-33 (2024)
Abstract Amyloid β42 (Aβ42) plays a decisive role in the pathology of Alzheimer’s disease. The Aβ42 peptide can aggregate into various supramolecular structures, with oligomers being the most toxic form. However, different Aβ species that cause
Externí odkaz:
https://doaj.org/article/4f151de0003645d299688fddb0eefb4d
Autor:
Rocio Alfaro-Ruiz, Alejandro Martín-Belmonte, Carolina Aguado, Ana Esther Moreno-Martínez, Yugo Fukazawa, Rafael Luján
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-16 (2024)
Abstract Synaptic dysfunction is an early feature in Alzheimer’s disease (AD) pathogenesis and a major morphological correlate of memory deficits. Given the main synaptic location of N-methyl-D-aspartate receptors (NMDARs), their dysregulation has
Externí odkaz:
https://doaj.org/article/dc5e597fa919457eaabb9d675def2f90
Autor:
Josefine Kappe, Felix Wittmann, Melanie Luppa, Maria Isabel Cardona, Solveign Weise, Stephan Fuchs, Robert Philipp Kosilek, Linda Sanftenberg, Christian Brettschneider, Juliane Döhring, Catharina Escales, David Czock, Birgitt Wiese, Jochen René Thyrian, Wolfgang Hoffmann, Thomas Frese, Jochen Gensichen, Hans-Helmut König, Hanna Kaduszkiewicz, Steffi Gerlinde Riedel-Heller
Publikováno v:
BMC Primary Care, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background General practitioners (GPs) play a crucial role in identifying cognitive impairment and dementia and providing post-diagnostic care. This study investigates (1) how promising GP consider lifestyle changes to maintain cognitive per
Externí odkaz:
https://doaj.org/article/a7b91def9aa847c0bed783bcd2b0c067
Autor:
Silvia Teixeira de Pinho, Angeliete Garcez Militão, Tatiane Gomes Teixeira, Mauricio Calomeni, Daniel Almeida Marinho, Vernon Furtado da Silva
Publikováno v:
Motricidade, Vol 20, Iss S1 (2024)
Alzheimer's disease (AD) is the most common neurodegenerative disease (Raskin et al., 2015). Noninvasive brain stimulation (NIBS) is another form of cognitive therapy that has received attention recently (Xu et al., 2019; Calomeni et al., 2017). To i
Externí odkaz:
https://doaj.org/article/a843a5bf40d04de99b9c03410ef2993a
Publikováno v:
Pharmacological Research, Vol 205, Iss , Pp 107247- (2024)
About 80 % of brain disorders have a genetic basis. The pathogenesis of most neurodegenerative diseases is associated with a myriad of genetic defects, epigenetic alterations (DNA methylation, histone/chromatin remodeling, miRNA dysregulation), and e
Externí odkaz:
https://doaj.org/article/4d97885196c74d7bb0aa63ff0436548f
Autor:
Afshin Kheradmand, Shayan Fallah, Mitra-Sadat Sadat-Shirazi, Ghorbangol Ashabi, Solmaz Khalifeh, Nayereh Zare
Publikováno v:
Archives of Advances in Biosciences, Vol 15, Iss 1, Pp 1-6 (2024)
Introduction: Alzheimerʼs disease (AD) has been identified as a progressive memory and cognitive impairment. Some Salvia species are suggested by certain studies for the management of mild to moderate AD. We aimed to evaluate the anti-inflammatory,
Externí odkaz:
https://doaj.org/article/7d4a84f841d84414acfa950ee0fc0d8d