Zobrazeno 1 - 10
of 17
pro vyhledávání: '"ALT, alternative lengthening of telomeres"'
Autor:
Satoru Ide, Asuka Sasaki, Yusuke Kawamoto, Toshikazu Bando, Hiroshi Sugiyama, Kazuhiro Maeshima
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-16 (2021)
Abstract Background Knowing chromatin components at a DNA regulatory element at any given time is essential for understanding how the element works during cellular proliferation, differentiation and development. A region-specific chromatin purificati
Externí odkaz:
https://doaj.org/article/fca7317f52a14d65bd0e426a803df5bf
Autor:
Toshikazu Bando, Hiroshi Sugiyama, Satoru Ide, Asuka Sasaki, Yusuke Kawamoto, Kazuhiro Maeshima
Publikováno v:
Epigenetics & Chromatin
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-16 (2021)
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-16 (2021)
Background Knowing chromatin components at a DNA regulatory element at any given time is essential for understanding how the element works during cellular proliferation, differentiation and development. A region-specific chromatin purification is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb964d9d119bdbc4222c6b6d84fd27c9
https://pubmed.ncbi.nlm.nih.gov/34627342
https://pubmed.ncbi.nlm.nih.gov/34627342
Autor:
Monica L. Guzman, Yi Feng, Mohamed O. Rabie, Eun Young Yu, Gail J. Roboz, Neal F. Lue, Nai-Kong V. Cheung, Irene Y. Cheung
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 7, Pp 689-701 (2019)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 7, Pp 689-701 (2019)
Telomeres play important roles in genome stability and cell proliferation. High risk neuroblastoma (HRNB), an aggressive childhood cancer, is especially reliant on telomere maintenance. Three recurrent genetic aberrations in HRNB (MYCN amplification,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d7095fac210e6387715a7e1ba3601e
https://doi.org/10.1016/j.neo.2019.04.002
https://doi.org/10.1016/j.neo.2019.04.002
Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 9, Pp 905-916 (2018)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
About 15% of human cancers counteract telomere loss by alternative lengthening of telomeres (ALT), which is attributed to homologous recombination (HR)-mediated events. But how telomeric HR leads to length elongation is poorly understood. Here, we ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c075d5ca31978fe2ee65205df1841c86
http://www.sciencedirect.com/science/article/pii/S1476558618302720
http://www.sciencedirect.com/science/article/pii/S1476558618302720
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 5, Pp 425-431 (2018)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Excess telomere shortening has been observed in most cancer cells. The telomere quantitative polymerase chain reaction (qPCR) assay has become an important tool for epidemiological studies examining the effects of aging, stress, and other factors on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1823b3d85a6600cd70db2ebe7797e5b
https://doi.org/10.1016/j.neo.2018.02.007
https://doi.org/10.1016/j.neo.2018.02.007
Akademický článek
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Autor:
Jennifer Fairlie, Lea Harrington
Publikováno v:
DNA Repair
Highlights • Telomere elongation decreases human tumour cell viability after irradiation. • The longer the telomeres, the greater the sensitivity to sub-lethal irradiation. • Increased sensitivity to irradiation is independent of telomere signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f219b77f032854fa2e343c7e4949fbf1
Akademický článek
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Autor:
Eid, Rita
Des mutations dans ATRX, une protéine de remodelage de la chromatine, ont été associées, dans plusieurs études cliniques, avec la voie télomérase-indépendante de maintenance des télomères (voie ALT) dans plusieurs types de cancer. Grâce à
Externí odkaz:
http://www.theses.fr/2015TOUR4021/document
Autor:
Cabuy, Erik
Telomeres are nucleoprotein complexes located at the end of chromosomes. They have an essential role in protecting chromosome ends. Telomerase or ALT (alternative lengthening of telomeres) mechanisms maintain telomeres by compensating natural telomer
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412795