Zobrazeno 1 - 10
of 906
pro vyhledávání: '"ALT, Alanine aminotransferase"'
Autor:
Caroline M. Sabotta, Suet-Ying Kwan, Lauren E. Petty, Jennifer E. Below, Aron Joon, Peng Wei, Susan P. Fisher-Hoch, Joseph B. McCormick, Laura Beretta
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Objective: Mexican Americans are disproportionally affected by non-alcoholic fatty liver disease (NAFLD), liver fibrosis and hepatocellular carcinoma. Noninvasive means to identify those in this population at high risk for these diseases are urgently
Externí odkaz:
https://doaj.org/article/df20d580aa9947ec9bc99e7e0778b6bc
Akademický článek
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Autor:
Wenchao Wei, Chi Chun Wong, Xiang Zhang, Jun Yu, Weixin Liu, Feixue Wang, Yunfei Zhou, Dabin Liu, Joseph J.Y. Sung
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 257-274 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Hepatic immune microenvironment plays a pivotal role in the development of nonalcoholic steatohepatitis (NASH). However, the role of natural killer (NK) cells, accounting for 10%–20% of liver lymphocytes, in NASH is still unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c28da1742a020c4b72f0c4a997351c0
http://www.sciencedirect.com/science/article/pii/S2352345X21001867
http://www.sciencedirect.com/science/article/pii/S2352345X21001867
Autor:
Chengjie Shan, Wenxin Jia, Minyi Qian, Lirui Wang, Bernd Schnabl, Dalei Wu, Nan Zhang, Yinan Zhang, Danyang Zhao, Meiling Zhang, Song Yang, Yufei Zhang, Yingsheng Gao, Quan Zhang, Chuyue Pan, Xu Shen, Jun Liu, Pengpeng Cai
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 233-256 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 233-256 (2022)
Background & Aims The ligand-activated transcription factor, aryl hydrocarbon receptor (AHR) can sense xenobiotics, dietary, microbial, and metabolic cues. Roles of Ahr in intestinal epithelial cells (IECs) have been much less elucidated compared wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec51e69e7577835c46cf4ef5134d8f2
https://doi.org/10.1016/j.jcmgh.2021.08.014
https://doi.org/10.1016/j.jcmgh.2021.08.014
Autor:
Ana M. Rojas, Natalia Ehrenhaus Masotta, Fabián Martínez-Perafán, Valeria Tripodi, Marta A. Carballo, Susana Gorzalczany
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 1229-1239 (2021)
Toxicology Reports, Vol 8, Iss, Pp 1229-1239 (2021)
Graphical abstract
Highlights • An oral high-dose CoQ10 oleogel was assessed in its genotoxicity and acute toxicity. • There was no genotoxic risk associated with the use of CoQ10 oleogel in volunteers. • Biochemical parameters remained wi
Highlights • An oral high-dose CoQ10 oleogel was assessed in its genotoxicity and acute toxicity. • There was no genotoxic risk associated with the use of CoQ10 oleogel in volunteers. • Biochemical parameters remained wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e42be4b9647c4ee2a5671c3ad690c4d
http://europepmc.org/articles/PMC8233171
http://europepmc.org/articles/PMC8233171
Akademický článek
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Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 322-339 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Fibrosis is a pathological reparative process that can occur in most organs and is responsible for nearly half of deaths in the developed world. Despite considerable research, few therapies have proven effective and been approved clinically for treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31e277e49b3a3364e9726d531259ad4
https://doi.org/10.1016/j.apsb.2020.09.001
https://doi.org/10.1016/j.apsb.2020.09.001
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 557-570 (2021)
Toxicology Reports, Vol 8, Iss, Pp 557-570 (2021)
Highlights • Four-week repeated-dose toxicity of intramuscular DSS was studied in minipigs. • DSS administration at ≥10 mg/kg/day causes toxicity and injection-site reaction. • The NOAEL of DSS after 4-week administration was 2 mg/kg/day in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b26ee397ae350858c363f15bad4a7b1
https://doi.org/10.1016/j.toxrep.2021.02.022
https://doi.org/10.1016/j.toxrep.2021.02.022
Akademický článek
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Akademický článek
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