Zobrazeno 1 - 10
of 661
pro vyhledávání: '"ALK gene"'
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-5 (2023)
Abstract Background Since the inception of targeted therapies in treating lung cancer, providers have had to be aware of a new host of side effects when selecting management options for patients. Although targeted therapies are creating increased hop
Externí odkaz:
https://doaj.org/article/82b88e43addb44659c2e777713f90591
Akademický článek
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Autor:
Yuzuna Aoki, MD, Masayuki Maeda, MD, PhD, Seiya Kishi, MD, Ryota Kogue, MD, PhD, Fumine Tanaka, MD, Maki Umino, MD, PhD, Mami Takeoka, MD, Ryo Hanaki, MD, PhD, Junya Hirayama, MD, PhD, Hiroto Yuasa, MD, Hiroshi Imai, MD, PhD, Masahiro Hirayama, MD, PhD, Hajime Sakuma, MD, PhD
Publikováno v:
Radiology Case Reports, Vol 17, Iss 10, Pp 3867-3870 (2022)
ALK-positive histiocytosis is an emerging histiocytic entity that can involve a single organ or multiple organs. This disease frequently involves the central nervous system, and the importance of immunohistochemical and genetic analyses is emphasized
Externí odkaz:
https://doaj.org/article/a985d667288a48b891f6f7a0552f8a0e
Autor:
Jianxin Chen, Junhui Wang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
ALK gene missense mutations are conventionally considered non-driver mutations without pathological significance, and therefore, there is a lack of effective target drugs against them. The standard treatment option for patients with ALK missense muta
Externí odkaz:
https://doaj.org/article/b0a7c3a93acd484ea9d20b10a8ca701d
Autor:
Neelam Sood, Binjul Juneja
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 66, Iss 4, Pp 842-844 (2023)
Benign fibrous histiocytoma also known as dermatofibroma is one of the common mesenchymal neoplasms. It commonly develops in young adult with female predominance and predilection for the extremities, particularly lower extremities. Implantation of ep
Externí odkaz:
https://doaj.org/article/0c63a2108e2f4006a7e0d33069c3c228
Publikováno v:
Journal of Pre-Clinical and Clinical Research, Vol 15, Iss 3, Pp 151-154 (2021)
Introduction . Currently, nearly 23,000 cases of lung cancer are diagnosed in Poland annually, of which 5% are cases with rearrangements in the ALK gene. In recent years, tremendous progress has been made in understanding the genetic makeup of this t
Externí odkaz:
https://doaj.org/article/30d77e1e7f454a258f0127a6317c0da6
Publikováno v:
PeerJ, Vol 10, p e14147 (2022)
Background Alkanes are important components of fossil energy, such as crude oil. The alkane monooxygenase encoded by alkB gene performs the initial step of alkane degradation under aerobic conditions. The alkB gene is well studied due to its ubiquity
Externí odkaz:
https://doaj.org/article/fffb5baf1b7749caaf2383f0e9f69bf3
Autor:
Matteo Canale, Elisabetta Petracci, Paola Cravero, Marita Mariotti, Gabriele Minuti, Giulio Metro, Vienna Ludovini, Sara Baglivo, Maurizio Puccetti, Alessandra Dubini, Giovanni Martinelli, Angelo Delmonte, Lucio Crinò, Paola Ulivi
Publikováno v:
Translational Oncology, Vol 23, Iss , Pp 101471- (2022)
Non-small-cell lung cancer (NSCLC) is the primary cause of cancer-related death. Gene rearrangements involving the anaplastic lymphoma kinase (ALK) tyrosine kinase identify a clinical and molecular subset of NSCLC patients, who benefit from the monot
Externí odkaz:
https://doaj.org/article/9fcffe32bbf24565b0725968e3ffe4ea
Autor:
Sheng-Yen Hsiao, Hong-Lin He, Teng-Song Weng, Cheng-Yao Lin, Chien-Ming Chao, Wen-Tsung Huang, Chao-Jung Tsao
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 1, Pp 232-238 (2021)
Anti-epithelial growth factor receptor or anti-vascular endothelial growth factor agents combined with chemotherapy were the standard of treatment for metastatic colorectal cancer (CRC). However, increasing evidence of molecularly stratified treatmen
Externí odkaz:
https://doaj.org/article/c942450403054456af2597f81ed59e1b
Autor:
Sara Akhavanfard, Erik Nohr, Mohammad AlNajjar, Mollie Haughn, Sayaka Hashimoto, Carol Deeg, Ruthann Pfau, Marie-Anne Brundler, Shalini C. Reshmi
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 1, Pp 585-591 (2021)
Neuroblastoma is the most common cancer in infants younger than 12 months of age, occurring with an incidence of 1 in 100,000 children. The clinical outcome of neuroblastoma ranges from spontaneous regression to treatment-resistant progression and/or
Externí odkaz:
https://doaj.org/article/0f7adf513d9144df8d44b43f2fe23a72