Association of liver abnormalities with in-hospital mortality in patients with COVID-19

Autor: Yong Li, Zeyang Ding, Yang Yang, Binhao Zhang, Chang Shu, Wei Wang, Yuwei Wang, Wei Zhu, Wanguang Zhang, Huaqiu Zhang, Jihong Liu, Tongtong Liu, Guannan Jin, Junbo Hu, Jia Song, Lin Chen, Wen-kui Yu, Ping Yin, Huan Feng, Hui Wang, Junnan Liang, Ganxun Li, Qian Chen, Zhouping Tang, Bixiang Zhang, Xiaoping Chen, Peng Zhu, Zhen-Yu Yin

Publikováno v: Journal of Hepatology

Background and Aims The evolution and clinical significance of abnormal liver chemistries and the impact of hepatitis B infection on outcome in patients with COVID-19 is not well characterized. This study aimed to explore these issues. Methods This l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3543f445abe1f64f8ff7d1ae96bd264
https://doi.org/10.1016/j.jhep.2020.12.012

Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury

Autor: Jan G. Hengstler, Eric J. C. Gálvez, Kai Markus Schneider, Lena Susanna Candels, Till Strowig, Christoph A. Thaiss, Michael Spiteller, Ina Bergheim, Eicke Latz, Benjamin Lelouvier, Ahmed Ghallab, Lijun Liao, Maiju Myllys, Anika Nier, Carolin V. Schneider, Antje Mohs, C Elfers, Sebastian Zuehlke, Alain Roulet, Konrad Kilic, Christian Trautwein, Amirouche Ouzerdine, Wenfang Gui, Theresa H. Wirtz

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 909-933 (2021)
Cellular and Molecular Gastroenterology and Hepatology, 11(4):909-933
Cellular and Molecular Gastroenterology and Hepatology : CMGH 11(4), 909-933 (2021). doi:10.1016/j.jcmgh.2020.11.002
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology
United Kingdom
United States

Background & Aims Acute liver failure (ALF) represents an unmet medical need in Western countries. Although the link between intestinal dysbiosis and chronic liver disease is well-established, there is little evidence for a functional role of gut-liv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c846d93f45d023f4eb14b075b03462
https://doi.org/10.1016/j.jcmgh.2020.11.002

ACE2, TMPRSS2 distribution and extrapulmonary organ injury in patients with COVID-19

Autor: Jie Zhang, Xuefeng Ma, Jie Tan, Yongning Xin, Likun Zhuang, Lizhen Chen, Mengzhen Dong, Shousheng Liu

Publikováno v: Biomedicine & Pharmacotherapy, Vol 131, Iss, Pp 110678-(2020)
Biomedicine & Pharmacotherapy

Graphical abstract
Highlights • Expressions of ACE2 and TMPRSS2 were observed in the extrapulmonary organs. • Direct infections of SARS-CoV-2 in extrapulmonary organs were observed in patients with COVID-19. • Clinical manifestation and ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21778d1ae80e7573ac46023bd6d54111
https://doi.org/10.1016/j.biopha.2020.110678

Acetaminophen-induced reduction of NIMA-related kinase 7 expression exacerbates acute liver injury.

Autor: Sun Z; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Wang Q; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Sun L; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Wu M; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Li S; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Hua H; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Sun Y; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu, China., Ni T; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Zhou C; Department of Pathology, Children's Hospital of Nanjing Medical University, Nanjing, China., Huang S; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Zhang A; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Zhang Y; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China., Jia Z; Nanjing Key Laboratory of Pediatrics, Children's Hospital of Nanjing Medical University, Nanjing, China.; Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China.

Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2022 Jul 20; Vol. 4 (10), pp. 100545. Date of Electronic Publication: 2022 Jul 20 (Print Publication: 2022).

Rodenticide (Yellow Phosphorus Poison)-Induced Hepatotoxicity in India: Constraints During Management.

Autor: Eapen CE; Department of Hepatology, Christian Medical College, Vellore, India., Venkataraman J; Department of Hepatology, Sri Ramachandra Institute of Higher Education & Research, Chennai, India.

Publikováno v: Journal of clinical and experimental hepatology [J Clin Exp Hepatol] 2021 Jul-Aug; Vol. 11 (4), pp. 414-417. Date of Electronic Publication: 2021 Apr 30.