Zobrazeno 1 - 10
of 16
pro vyhledávání: '"ALEXANDER W. TEASS"'
Autor:
Dale W. Porter, Jeffery McLaurin, Kurt Brumbaugh, Vincent Castranova, Christoper M. Beighley, Lyndell Millecchia, Alexander W. Teass, Dawn Ramsey, Amir Khan, Victor A. Robinson, Patsy Willard
Publikováno v:
Toxicological Sciences. 90:188-197
Our laboratory has previously reported results from a rat silica inhalation study which determined that, even after silica exposure ended, pulmonary inflammation and damage progressed with subsequent fibrosis development. In the present study, the re
Autor:
Dawn Ramsey, Kurt Brumbaugh, Vincent Castranova, Lori A. Battelli, Victor A. Robinson, Amir Khan, Alexander W. Teass, Ann F. Hubbs, Dale W. Porter, Robert R. Mercer, Jeff McLaurin
Publikováno v:
Toxicological Sciences. 79:370-380
Human epidemiologic studies have found that silicosis may develop or progress even after occupational exposure has ended, suggesting that there is a threshold lung burden above which silica-induced pulmonary disease progresses without further exposur
Autor:
Jeff McLaurin, Victor A. Robinson, Alexander W. Teass, Douglas Landsittel, Patsy Willard, Donna Pack, Dawn Ramsey, Ann F. Hubbs, Dale W. Porter, Lyndell Millecchia, Vincent Castranova, Amir Khan
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 283:L485-L493
In previous reports from this study, measurements of pulmonary inflammation, bronchoalveolar lavage cell cytokine production and nuclear factor-κB activation, cytotoxic damage, and fibrosis were detailed. In this study, we investigated the temporal
Autor:
Vincent Castranova, Mark Barger, Amir Khan, Jane Ma, Dale W. Porter, Jeff McLaurin, Dawn Ramsey, Douglas Landsittel, Jianping Ye, Alexander W. Teass, Victor A. Robinson
Publikováno v:
Inhalation Toxicology. 14:349-367
In vitro studies suggest that silica-induced lung disease may be linked to processes regulated by nuclear factor-kappa B (NF-kappa B) activation, but this has not been examined in vivo. Rats were exposed to a silica aerosol of 15 mg/m(3) (6 h/day, 5
Autor:
Gabriele Sabbioni, D. Gayle DeBord, Kenneth K. Brown, Avima M. Ruder, Robert P. Streicher, Dennis R. Roberts, Elizabeth M. Ward, Alexander W. Teass, Glenn Talaska
Publikováno v:
JNCI Journal of the National Cancer Institute. 88:1046-1053
Background: In April 1991, an excess of bladder cancer cases among workers employed at a chemical manufacturing facility in Niagara Falls, NY, was reported. This excess was primarily confined to 708 workers who had ever been employed in the rubber ch
Publikováno v:
Applied Occupational and Environmental Hygiene. 10:557-565
A urinalysis method for o-toluidine and aniline was developed for biological monitoring. Urine specimens were made 4.7 M in sodium hydroxide and heated at 80°C for 2 hours to convert the metabolites acetanilide and N-acetyl-o-toluidine to the free a
Publikováno v:
Applied Occupational and Environmental Hygiene. 7:231-240
A method for the estimation of formaldehyde dose from inhalable dust/fibers using a commercially available inhalable sampler was developed. Filters containing sampled dust/fibers were placed in 10 ml of distilled water and incubated at 37°C for 4 ho
Autor:
Vincent Castranova, Lyndell Millecchia, Alexander W. Teass, Jane Y. C. Ma, Ann F. Hubbs, Dale W. Porter
Publikováno v:
Oxygen/Nitrogen Radicals: Cell Injury and Disease ISBN: 9781461353881
Numerous investigations have been conducted to elucidate mechanisms involved in the initiation and progression of silicosis. However, most of these studies involved bolus exposure of rats to silica, i.e. intratracheal instillation or a short duration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90370e86df206be265984347286a67d2
https://doi.org/10.1007/978-1-4615-1087-1_20
https://doi.org/10.1007/978-1-4615-1087-1_20
Publikováno v:
Clinical Chemistry. 48:1604-1605
In the course of investigating the exposure of gold miners and other workers to mercury, investigators at the National Institute for Occupational Safety & Health (NIOSH) measured urine N -acetyl-β-d-glucosaminidase (NAG; EC 3.2.1.52) activity to mon
Publikováno v:
Applied Industrial Hygiene. 3:274-279
The sampling of 2-furaldehyde, pentanedial, and pentanal from air has been accomplished using sorbent tubes containing 120-mg and 60-mg beds of XAD-2 coated with 10 percent 2-(hydroxymethyl)piperidine. Samples were collected at ca. 50 cm3/min for a m