Zobrazeno 1 - 10
of 48
pro vyhledávání: '"ALEXANDER E. KARU"'
Autor:
Jean-Luc Pellequer, Victoria A. Roberts, Shu-wen W. Chen, Alexander E. Karu, Qing X. Li, Young-Soo Keum
Publikováno v:
Journal of Molecular Recognition
Journal of Molecular Recognition, 2005, 18, pp.282-294. ⟨10.1002/jmr.740⟩
Journal of Molecular Recognition, 2005, 18, pp.282-294. ⟨10.1002/jmr.740⟩
Polychlorinated biphenyls (PCBs) are a family of 209 isomers (congeners) with a wide range of toxic effects. In structural terms, they are of two types: those with and those without chlorines at the ortho positions (2, 2′, 6 and 6′). Only 20 cong
Publikováno v:
Journal of Agricultural and Food Chemistry. 50:3380-3389
A set of haptens structurally resembling the herbicide imazethapyr (PURSUIT) was synthesized and used to derive monoclonal antibodies (MAbs) and direct and indirect competition enzyme immunoassays (EIAs) which could detect imazethapyr, imazaquin (SCE
Publikováno v:
Analytical Chemistry. 73:5477-5484
A previously described monoclonal antibody, S2B1, was highly selective for coplanar (non-ortho-chlorinated) PCB congeners in enzyme immunoassays that measured binding at equilibrium. In the present study, kinetic exclusion fluoroimmunoassay (KinExA)
Publikováno v:
Analytica Chimica Acta. 419:1-8
Several approaches were investigated to fully use an enzyme linked immunosorbent assay (ELISA) for accurate measurement of polycyclic aromatic hydrocarbons (PAHs) and their degradation products in surface water and sediment collected from the Pearl H
Autor:
Qing X. Li, Kai Li, Mei Liu, Victoria A. Roberts, Rongliang Chen, Alexander E. Karu, Bitao Zhao
Publikováno v:
Analytical Chemistry. 71:302-309
As a first step toward developing sensitive enzyme-linked immunosorbent assays (ELISAs) for multianalyte detection of polycyclic aromatic hydrocarbons (PAHs), haptens with different lengths of carboxylic acid spacers at various positions were derived
Publikováno v:
Journal of Agricultural and Food Chemistry. 45:1509-1517
The Fab domain sequences from messenger RNA of a mouse hybridoma cell line secreting a monoclonal antibody (MAb) specific for the phenylurea herbicide diuron were amplified and inserted into the M13 phagemid vector pComb8. Phage displaying diuron-spe
Publikováno v:
Analytical Chemistry. 67:3829-3839
Polychlorinated biphenyls (PCBs) are ubiquitous environmental pollutants with diverse toxic, teratogenic, reproductive, immunotoxic, and tumorigenic effects. Three of the least abundant of the 209 PCB isomers (congeners) are the most toxic and most d
Publikováno v:
Journal of Agricultural and Food Chemistry. 42:310-315
Diuron is one of the most heavily used herbicides in California, and well water and surface water are routinely monitored for diuron residues. In a previous paper, we described haptens and monoclonal antibodies suitable for quantitative competition e
Autor:
Michael W. Bigelow, Bruce D. Hammock, Marvin H. Goodrow, Douglas J. Schmidt, Alexander E. Karu
Publikováno v:
Journal of Agricultural and Food Chemistry. 42:301-309
Diuron and related phenylurea herbicides and their metabolites are important candidates for sensitive and specific immunodetection. This paper describes a scheme for the synthesis of two different types of phenylurea haptens for immunization and use
Publikováno v:
Food and Agricultural Immunology. 6:371-384
Quantitative competition immunoassays with appropriate combinations of antibodies give consistent dose‐response patterns which may be used to identify and estimate amounts of cross‐reacting compounds. Previously reported methods of analyzing cros