Zobrazeno 1 - 10
of 595
pro vyhledávání: '"ALBERT I. MEYERS"'
Publikováno v:
Tetrahedron. 58:207-213
Addition of sulfonyl carbanions with or without an electrophilic tether has been shown, under certain conditions, to add to α,β-unsaturated oxazolines in good yields and high de's. When 4-bromobutylsulfonyl carbanions are added to unsaturated oxazo
Publikováno v:
The Journal of Organic Chemistry. 66:6037-6045
Synthesis of protected tetradehydro-(6,6'-S)-(14,14'-S)-(16,16'-R)-disorazole (3), a potential precursor to the natural product disorazole C1 (1), is described. Key features of this work include (a) an unprecedented sequential 1,5 O --O silyl rearran
Autor:
Albert W. Kruger, Albert I. Meyers
Publikováno v:
Tetrahedron Letters. 42:4301-4304
Three enantiomerically and geometrically pure building blocks representing fragments of the antifungal antibiotic viridenomycin have been prepared.
Publikováno v:
Tetrahedron Letters. 42:4305-4308
A second generation approach toward the synthesis of viridenomycin is described. Three key fragments of the molecule have been synthesized in stereochemically pure form. Initial studies toward the coupling of these fragments with the aim of assemblin
Publikováno v:
Tetrahedron. 57:2635-2642
Cyclobutannulation of the bicyclic lactam with allyldimethyltritylsilane is accomplished in high yield with good diastereoselectivity. The resulting tricyclic system is converted to a enantiomerically pure cyclobutane-fused pyrrolidine.
Autor:
Albert I. Meyers, Mark F. Mechelke
Publikováno v:
Tetrahedron Letters. 41:9377-9381
The enantioselective synthesis of branched polyhydroxylated pyrrolidines from a novel α-methylene bicyclic lactam (4b) is described.
Autor:
Michael D. Groaning, Albert I. Meyers
Publikováno v:
Tetrahedron. 56:9843-9873
Autor:
Kozo Oda, Albert I. Meyers
Publikováno v:
Tetrahedron Letters. 41:8193-8197
Chiral 3-alkyl-3-arylpyrrolidines were prepared from the substituted bicyclic lactams. Stereoselectivity in the alkylation of bicyclic lactams was improved by using an alkyl triflate or tosylate as the electrophile.
Autor:
Alex G. Waterson, Albert I. Meyers
Publikováno v:
The Journal of Organic Chemistry. 65:7240-7243
Autor:
Mark F. Mechelke, Albert I. Meyers
Publikováno v:
Tetrahedron Letters. 41:4339-4342
The enantioselective synthesis of (+)-euphococcinine (1), a homotropane alkaloid, has been achieved in five steps from bicyclic lactam 5.