Zobrazeno 1 - 10
of 24
pro vyhledávání: '"ALAN S. GELBARD"'
Autor:
Roy S. Tilbury, Alan S. Gelbard
Publikováno v:
Radiotracers for Medical Applications ISBN: 9780429278822
Radiotracers for Medical Applications
Radiotracers for Medical Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7c77b309c1ab6f79ecd154d226dd990
https://doi.org/10.1201/9780429278822-8
https://doi.org/10.1201/9780429278822-8
Publikováno v:
Microbiology. 144:2629-2638
Sinorhizobium meliloti 1021 and Rhizobium etli CE3 turn over nitrogen and carbon from glutamine to ammonium and CO2, respectively. Some of the ammonium released is assimilated back into glutamine, indicating that a glutamine cycle similar to that in
Publikováno v:
Advances in Enzymology and Related Areas of Molecular Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecb821b56900a07a8d53f3d945d781dc
https://doi.org/10.1002/9780470123034.ch4
https://doi.org/10.1002/9780470123034.ch4
Publikováno v:
Journal of neurochemistry. 61(5)
Certain halogenated hydrocarbons, e.g., dichloroacetylene, are nephrotoxic to experimental animals and neurotoxic to humans; cysteine-S-conjugate beta-lyases may play a role in the nephrotoxicity. We now show that with dichlorovinylcysteine as substr
Autor:
Yasuhisa Asano, Sabina Filc-DeRicco, Karen C. Rosenspire, Edward Nieves, Arthur J.L. Cooper, Alan S. Gelbard
Publikováno v:
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes. 41(2)
L-[13N]Tyrosine and L-[13N]phenylalanine were synthesized using immobilized enzymes by two methods. In method 1, [13N]ammonia is converted to L-[13N]glutamate; transamination with p-hydroxyphenylpyruvate yields L-[13N]tyrosine. [13N]Tyrosine is separ
Publikováno v:
Radiology. 142:495-500
Eleven patients with untreated primary Ewing sarcoma were studied with intravenously administered 13N-labeled L-glutamate. Seven were repeatedly scanned during chemotherapy using this agent and 99mTc-methylene diphosphonate (99mTc-MDP). The untreated
Autor:
Gerald Rosen, Alan S. Gelbard, Richard S. Benua, Andrew G. Huvos, Robert E. Reiman, John S. Laughlin
Publikováno v:
Cancer. 48:1976-1981
An investigation was performed to correlate the regional uptake of N-13 L-glutamate with histologic changes in tumor tissue in patients undergoing adjuvant chemotherapy for osteogenic sarcoma. A parametric image was produced by calculating the ratio
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 843:37-48
The short-term metabolic fate of labeled nitrogen derived from [13N]ammonia or from L-[amide-13N]glutamine was determined in murine tumors known to be resistant (Ridgeway Osteogenic Sarcoma (ROS] or sensitive (Sarcoma-180 (S-180)) to glutaminase ther
Autor:
Alan S. Gelbard
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 18:933-945
The progress that has been made in incorporating the short-lived, positron-emitting isotopes N-13 and C-11, into biologically active compounds by biosynthetic means is reviewed. These methods include the use of whole cells or plant leaves to carry ou
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 21:803-814
NH2OH was labeled with a β+emitter (13N, t1/2 = 9 96 min.). Hydroxyl[13N]amine was synthesized from HSO and [13N]nitrite (produced via the 160(p,α)13N reaction by proton bombardment of H2O). The synthesis reactions are: Hydroxyl[13N]amine was purif