Zobrazeno 1 - 10
of 34
pro vyhledávání: '"AL Guyatt"'
Autor:
RJ Packer, N Shrine, R Hall, CA Melbourne, R Thompson, AT Williams, ML Paynton, AL Guyatt, PH Lee, C John, A Campbell, C Hayward, M de Vries, JM Vonk, J Davitte, E Hessel, D Michalovich, JC Betts, I Sayers, A Yeo, IP Hall, MD Tobin, LV Wain
BackgroundChronic sputum production impacts on quality of life and is a feature of many respiratory diseases. Identification of the genetic variants associated with chronic sputum production in a disease agnostic sample could improve understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0807dee241dc34e2c14db70ea93cc92b
https://doi.org/10.1101/2022.01.11.22269075
https://doi.org/10.1101/2022.01.11.22269075
Autor:
Martin CA; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK., Woolf K; University College London Medical School, London, UK., Bryant L; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Carr S; Department of Nephrology, University Hospitals of Leicester NHS Trust, Leicester, UK.; General Medical Council, London, UK., Gray LJ; Biostatistics Research Group, Department of Health Sciences, University of Leicester, Leicester, UK., Gupta A; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Guyatt AL; Department of Health Sciences, University of Leicester, Leicester, UK., John C; Department of Health Sciences, University of Leicester, Leicester, UK., Melbourne C; Genetic Epidemiology Research Group, Department of Health Sciences, University of Leicester, Leicester, UK., McManus IC; University College London Medical School, London, UK., Nazareth J; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK., Nellums LB; Population and Lifespan Sciences, School of Medicine, University of Nottingham, Nottingham, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK., Pan D; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK., Khunti K; Diabetes Research Centre, University of Leicester, Leicester, UK., Pareek M; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK.
Publikováno v:
The Lancet regional health. Europe [Lancet Reg Health Eur] 2024 Nov 21; Vol. 48, pp. 101148. Date of Electronic Publication: 2024 Nov 21 (Print Publication: 2025).
Autor:
Shrine N; Department of Health Sciences, University of Leicester, Leicester, UK., Guyatt AL; Department of Health Sciences, University of Leicester, Leicester, UK., Erzurumluoglu AM; Department of Health Sciences, University of Leicester, Leicester, UK., Jackson VE; Department of Health Sciences, University of Leicester, Leicester, UK.; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Hobbs BD; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Melbourne CA; Department of Health Sciences, University of Leicester, Leicester, UK., Batini C; Department of Health Sciences, University of Leicester, Leicester, UK., Fawcett KA; Department of Health Sciences, University of Leicester, Leicester, UK., Song K; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Sakornsakolpat P; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Li X; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Boxall R; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK., Reeve NF; Department of Health Sciences, University of Leicester, Leicester, UK., Obeidat M; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada., Zhao JH; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wielscher M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Kentistou KA; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Sun BB; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhou J; Flatiron Institute, Simons Foundation, New York, NY, USA., Hui J; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Population Health, The University of Western Australia, Crawley, Western Australia, Australia.; PathWest Laboratory Medicine of WA, Sir Charles Gairdner Hospital, Crawley, Western Australia, Australia.; School of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia., Karrasch S; Institute of Epidemiology, Helmholtz Zentrum Muenchen-German Research Center for Environmental Health, Neuherberg, Germany.; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-Universität, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany., Imboden M; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Enroth S; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala Universitet, Uppsala, Sweden., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Surakka I; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; The National Institute for Health and Welfare (THL), Helsinki, Finland., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Allen RJ; Department of Health Sciences, University of Leicester, Leicester, UK., Bakke PS; Department of Clinical Science, University of Bergen, Bergen, Norway., Beaty TH; Department of Epidemiology, Johns Hopkins University School of Public Health, Baltimore, MD, USA., Bleecker ER; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Bossé Y; Department of Molecular Medicine, Laval University, Québec, Canada.; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Québec, Canada., Brandsma CA; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, GRIAC Research Institute, University of Groningen, Groningen, The Netherlands., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Crapo JD; National Jewish Health, Denver, CO, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK.; Department of Human Genetics, Wellcome Trust Sanger Institute, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., DeMeo DL; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Dudbridge F; Department of Health Sciences, University of Leicester, Leicester, UK., Ewert R; Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany., Gulsvik A; Department of Clinical Science, University of Bergen, Bergen, Norway., Hansell AL; Centre for Environmental Health & Sustainability, University of Leicester, Leicester, UK.; UK Small Area Health Statistics Unit, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, St Mary's Hospital, London, UK., Hao K; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hoffman JD; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Hokanson JE; Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Joshi PK; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Joubert P; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Québec, Canada.; Department of Molecular Biology, Medical Biochemistry, and Pathology, Laval University, Québec, Canada., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Li X; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada., Li L; Department of Epidemiology & Biostatistics, Peking University Health Science Center, Beijing, China., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Locantore N; GSK R&D, Collegeville, PA, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Maranville JC; MRL, Merck & Co., Inc, Kenilworth, NJ, USA., Murray A; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK., Nickle DC; MRL, Merck & Co., Inc, Kenilworth, NJ, USA.; Gossamer Bio, San Diego, CA, USA., Packer R; Department of Health Sciences, University of Leicester, Leicester, UK., Parker MM; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Paynton ML; Department of Health Sciences, University of Leicester, Leicester, UK., Porteous DJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Prokopenko D; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Qiao D; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rawal R; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Runz H; MRL, Merck & Co., Inc, Kenilworth, NJ, USA., Sayers I; Division of Respiratory Medicine and NIHR-Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Sin DD; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada.; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Artigas MS; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain., Sparrow D; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Tal-Singer R; GSK R&D, Collegeville, PA, USA., Timmers PRHJ; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Van den Berge M; University of Groningen, University Medical Center Groningen, Department of Pulmonology, GRIAC Research Institute, University of Groningen, Groningen, The Netherlands., Whittaker JC; Target Sciences - R&D, GSK Medicines Research Centre, Stevenage, UK., Woodruff PG; UCSF Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, CA, USA., Yerges-Armstrong LM; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Troyanskaya OG; Department of Computer Science, Princeton University, Princeton, NJ, USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Polašek O; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; University of Split School of Medicine, Split, Croatia., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala Universitet, Uppsala, Sweden., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Probst-Hensch NM; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Schulz H; Institute of Epidemiology, Helmholtz Zentrum Muenchen-German Research Center for Environmental Health, Neuherberg, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany., James AL; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Medicine and Pharmacology, The University of Western Australia, Crawley, Western Australia, Australia., Wilson JF; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Stubbe B; Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Zeggini E; Wellcome Sanger Institute, Hinxton, UK.; Institute of Translational Genomics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UK., Wareham N; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Silverman EK; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Scott RA; Target Sciences - R&D, GSK Medicines Research Centre, Stevenage, UK., Walters RG; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Meyers DA; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Hall IP; Division of Respiratory Medicine and NIHR-Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK. mt47@leicester.ac.uk.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK. mt47@leicester.ac.uk., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK. lvw1@leicester.ac.uk.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK. lvw1@leicester.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2024 May; Vol. 56 (5), pp. 1032-1033.
Autor:
Guyatt AL; Department of Population Health Sciences, University of Leicester, Leicester, UK.; These authors are joint first authors., Cai YS; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Centre for Environmental Health and Sustainability, University of Leicester, Leicester, UK.; National Institute for Health and Care Research Health Protection Research Unit in Environmental Exposures and Health, University of Leicester, Leicester, UK.; National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust, Research & Innovation, Leicester General Hospital, Leicester, UK.; These authors are joint first authors., Doiron D; Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University, Montréal, QC, Canada., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK.; National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust, Research & Innovation, Leicester General Hospital, Leicester, UK., Hansell AL; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Centre for Environmental Health and Sustainability, University of Leicester, Leicester, UK.; National Institute for Health and Care Research Health Protection Research Unit in Environmental Exposures and Health, University of Leicester, Leicester, UK.; National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust, Research & Innovation, Leicester General Hospital, Leicester, UK.
Publikováno v:
ERJ open research [ERJ Open Res] 2024 Apr 29; Vol. 10 (2). Date of Electronic Publication: 2024 Apr 29 (Print Publication: 2024).
Autor:
Higbee DH; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, UK.; Academic Respiratory Unit, University of Bristol, Southmead Hospital, Bristol, UK., Lirio A; Department of Population Health Sciences, University of Leicester, Leicester, UK., Hamilton F; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, UK., Granell R; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, UK., Wyss AB; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC., London SJ; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC., Bartz TM; Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington, Seattle, WA., Gharib SA; Computational Medicine Core, Center for Lung Biology, UW Medicine Sleep Center, Department of Medicine, University of Washington, Seattle, WA., Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA.; Harvard Medical School, Boston, MA., Wan E; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA.; Harvard Medical School, Boston, MA.; Pulmonary and Critical Care Section, Department of Medicine, VA Boston Healthcare System, Boston, MA, USA., Silverman E; Pulmonary and Critical Care Section, Department of Medicine, VA Boston Healthcare System, Boston, MA, USA., Crapo JD; Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, Colorado., Lominchar J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen., Dantoft T; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital., Kårhus L; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital., O'Connor GT; Pulmonary Center, School of Medicine, Boston University, Boston, Massachusetts.; Division of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Boston Medical Center, Boston, Massachusetts., Dupuis J; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada., Xu H; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts., De Vries MM; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands., Hu X; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA., Barr RG; Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA., Wijnant SRA; Department of Bioanalysis, Ghent University, Ghent, Belgium.; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium., Brusselle GG; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.; Department of Epidemiology, Department of Respiratory Medicine, Erasmus MC, Rotterdam, the Netherlands., Lahouse L; Department of Bioanalysis, Ghent University, Ghent, Belgium.; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Li X; Centre for Heart Lung Innovation, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada., Hernández Cordero AI; Centre for Heart Lung Innovation, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada., Obeidat M; Centre for Heart Lung Innovation, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada., Sin DD; Centre for Heart Lung Innovation, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada.; Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Harris SE; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK., Redmond P; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK., Taylor AM; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK., Cox SR; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, UK., Williams AT; Department of Population Health Sciences, University of Leicester, Leicester, UK., Shrine N; Department of Population Health Sciences, University of Leicester, Leicester, UK., John C; Department of Population Health Sciences, University of Leicester, Leicester, UK., Guyatt AL; Department of Population Health Sciences, University of Leicester, Leicester, UK., Hall IP; University of Nottingham and NIHR Nottingham Biomedical Research Centre., Smith GD; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Biomedical Research Centre, Leicester, UK.; joint senior authors., Dodd JW; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, UK james.dodd@bristol.ac.uk.; Academic Respiratory Unit, University of Bristol, Southmead Hospital, Bristol, UK.; joint senior authors.
Publikováno v:
The European respiratory journal [Eur Respir J] 2023 Dec 22. Date of Electronic Publication: 2023 Dec 22.
Autor:
Shrine N; Department of Population Health Sciences, University of Leicester, Leicester, UK. nick.shrine@leicester.ac.uk., Izquierdo AG; Department of Population Health Sciences, University of Leicester, Leicester, UK., Chen J; Department of Population Health Sciences, University of Leicester, Leicester, UK., Packer R; Department of Population Health Sciences, University of Leicester, Leicester, UK., Hall RJ; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Guyatt AL; Department of Population Health Sciences, University of Leicester, Leicester, UK., Batini C; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Thompson RJ; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Pavuluri C; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Malik V; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Hobbs BD; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Moll M; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Kim W; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Tal-Singer R; COPD Foundation, Washington DC, USA., Bakke P; Department of Clinical Science, Unversity of Bergen, Bergen, Norway., Fawcett KA; Department of Population Health Sciences, University of Leicester, Leicester, UK., John C; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Coley K; Department of Population Health Sciences, University of Leicester, Leicester, UK., Piga NN; Department of Population Health Sciences, University of Leicester, Leicester, UK., Pozarickij A; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Millwood IY; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Li L; Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China., Wijnant SRA; Department of Respiratory Diseases, Ghent Universital Hospital, Ghent, Belgium.; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.; Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands., Lahousse L; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.; Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands., Brusselle G; Department of Respiratory Diseases, Ghent Universital Hospital, Ghent, Belgium.; Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands., Uitterlinden AG; Department of Internal Medicine, Eramus Medical Center, Rotterdam, The Netherlands., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Oelsner EC; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Barr RG; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Wielscher M; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Imboden M; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Department of Public Health, University of Basel, Basel, Switzerland., Jeong A; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Department of Public Health, University of Basel, Basel, Switzerland., Bartz TM; Cardiovascular Health Research Unit, Departments of Medicine and Biostatistics, University of Washington, Seattle, WA, USA., Gharib SA; Computational Medicine Core, Center for Lung Biology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA., Flexeder C; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Karrasch S; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Gieger C; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Peters A; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute for Medical Information Processing, Biometry and Epidemiology, Medical Faculty, Ludwig Maximilian University, Munich, Germany., Stubbe B; Department of Internal Medicine B-Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Hu X; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Ortega VE; Division of Respiratory Medicine, Department of Internal Medicine, Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ, USA., Meyers DA; Department of Medicine, University of Arizona, Tucson, AZ, USA., Bleecker ER; Department of Medicine, University of Arizona, Tucson, AZ, USA., Gabriel SB; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gupta N; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Smith AV; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Zhao JH; Department of Public and Primary Care, Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Hansen AF; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Trondheim, Norway., Langhammer A; HUNT Research Centre, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Levanger, Norway.; Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway., Willer C; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Bhatta L; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Trondheim, Norway., Porteous D; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Sofer T; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Lee J; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Daviglus ML; Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA., Yu B; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Lim E; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Xu H; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., O'Connor GT; Pulmonary Center, School of Medicine, Boston University, Boston, MA, USA., Thareja G; Bioinformatics Core, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar., Albagha OME; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.; Center for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Suhre K; Bioinformatics Core, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar.; Department of Biophysics and Physiology, Weill Cornell Medicine, New York, NY, USA., Granell R; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Faquih TO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Hiemstra PS; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Slats AM; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Mullin BH; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia., Hui J; Busselton Population Medical Research Institute, QEII Medical Centre, Nedlands, Western Australia, Australia.; School of Population and Global Health, University of Western Australia, Crawley, Western Australia, Australia.; PathWest Laboratory Medicine of WA, Nedlands, Western Australia, Australia., James A; Busselton Population Medical Research Institute, QEII Medical Centre, Nedlands, Western Australia, Australia., Beilby J; School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia.; Busselton Population Medical Research Institute, QEII Medical Centre, Nedlands, Western Australia, Australia., Patasova K; Department of Twin Research and Genetic Epidemiology, King's College London School of Medicine, London, UK.; Division of Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Hysi P; Department of Twin Research and Genetic Epidemiology, King's College London School of Medicine, London, UK.; UCL Institute of Ophthalmology, University College London, London, UK., Koskela JT; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Wyss AB; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA., Jin J; Westat, Durham, NC, USA., Sikdar S; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA.; Department of Mathematics and Statistics, Old Dominion University, Norfolk, VA, USA., Lee M; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA., May-Wilson S; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Pirastu N; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Kentistou KA; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Joshi PK; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Timmers PRHJ; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Williams AT; Department of Population Health Sciences, University of Leicester, Leicester, UK., Free RC; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Wang X; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Morrison JL; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Gilliland FD; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Chen Z; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Wang CA; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia., Foong RE; Wal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, Western Australia, Australia.; School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia., Harris SE; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Taylor A; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Redmond P; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Cook JP; Department of Health Data Science, University of Liverpool, Liverpool, UK., Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Genentech, South San Francisco, CA, USA., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Palviainen T; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Kaprio J; Institute for Molecular Medicine Finland-FIMM, University of Helsinki, Helsinki, Finland., Rantanen T; Faculty of Sport and Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland., Pietiläinen KH; Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Obesity and Abdominal Centers, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Cox SR; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Pennell CE; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia.; Department of Maternity and Gynaecology, John Hunter Hospital, Newcastle, New South Wales, Australia., Hall GL; Wal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, Western Australia, Australia.; School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia., Gauderman WJ; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Brightling C; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK.; Department of Infection, Inflammation and Immunity, Institute for Lung Health, University of Leicester, Leicester, UK., Wilson JF; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK., Vasankari T; FILHA-Finnish Lung Health Association, Helsinki, Finland.; Department of Respiratory Diseases and Allergology, University of Turku, Turku, Finland., Laitinen T; Administration Center, Tampere University Hospital and University of Tampere, Tampere, Finland., Salomaa V; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Timpson NJ; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; ALSPAC, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Zeggini E; Wellcome Sanger Institute, Cambridge, UK.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich (TUM) and Klinikum Rechts der Isar, TUM School of Medicine, Munich, Germany., Dupuis J; Department of Epidemiology, Biostatistics, and Occupational Health, School of Population and Global Health, McGill University, Montreal, Quebec, Canada., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Brumpton B; HUNT Research Centre, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Levanger, Norway.; Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, UK.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK.; Computational Medicine, Berlin Institute of Health at Charité, Universitätsmedizin Berlin, Berlin, Germany., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Schmidt CO; Institute for Community Medicine, SHIP-Clinical Epidemiological Research, University Medicine Greifswald, Greifswald, Germany., Probst-Hensch N; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Department of Public Health, University of Basel, Basel, Switzerland., Jarvelin MR; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Polasek O; School of Medicine, University of Split, Split, Croatia., Rudan I; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK., Lee JH; Jeffrey Cheah Biomedical Centre, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Sayers I; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Rawlins EL; Wellcome Trust-CRUK Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Dudbridge F; Department of Population Health Sciences, University of Leicester, Leicester, UK., Silverman EK; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Strachan DP; Population Health Research Institute, St George's University of London, London, UK., Walters RG; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK., London SJ; Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA., Cho MH; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Hall IP; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK. martin.tobin@leicester.ac.uk.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK. martin.tobin@leicester.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2023 Oct; Vol. 55 (10), pp. 1778-1779.
Autor:
Packer RJ; Department of Population Health Sciences, University of Leicester, Leicester, UK richard.packer@leicester.ac.uk.; Leicester NIHR Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Shrine N; Department of Population Health Sciences, University of Leicester, Leicester, UK., Hall R; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Melbourne CA; Department of Population Health Sciences, University of Leicester, Leicester, UK., Thompson R; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Williams AT; Department of Population Health Sciences, University of Leicester, Leicester, UK., Paynton ML; Department of Population Health Sciences, University of Leicester, Leicester, UK., Guyatt AL; Department of Population Health Sciences, University of Leicester, Leicester, UK., Allen RJ; Department of Population Health Sciences, University of Leicester, Leicester, UK., Lee PH; Department of Population Health Sciences, University of Leicester, Leicester, UK., John C; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., de Vries M; University of Groningen, University Medical Center Groningen, Department of Epidemiology and Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands., Vonk JM; University of Groningen, University Medical Center Groningen, Department of Epidemiology and Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands., Davitte J; GSK R&D, Collegeville, PA, USA., Hessel E; GSK R&D, Stevenage, UK., Michalovich D; GSK R&D, Stevenage, UK., Betts JC; GSK R&D, Stevenage, UK., Sayers I; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Yeo A; GSK R&D, Stevenage, UK., Hall IP; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Publikováno v:
The European respiratory journal [Eur Respir J] 2023 Jun 15; Vol. 61 (6). Date of Electronic Publication: 2023 Jun 15 (Print Publication: 2023).
Autor:
Packer RJ; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK.; Leicester National Institute of Health and Care Research Biomedical Research Centre, Glenfield Hospital, Leicester LE5 4PW, UK., Williams AT; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK., Hennah W; Orion Pharma, Espoo 02200, Finland.; Neuroscience Center, HiLIFE, University of Helsinki, Helsinki 00100, Finland.; Institute for Molecular Medicine FIMM, HiLIFE, University of Helsinki, Helsinki 00100, Finland., Eisenberg MT; Department of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK., Shrine N; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK., Fawcett KA; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK., Pearson W; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK., Guyatt AL; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK., Edris A; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK.; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Gent 9000, Belgium., Hollox EJ; Department of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK., Marttila M; Orion Pharma, Espoo 02200, Finland., Rao BS; Orion Pharma, Nottingham NG1 2GB, UK., Bratty JR; Orion Pharma, Nottingham NG1 2GB, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK.; Leicester National Institute of Health and Care Research Biomedical Research Centre, Glenfield Hospital, Leicester LE5 4PW, UK., Dudbridge F; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester LE1 7RH, UK.; Leicester National Institute of Health and Care Research Biomedical Research Centre, Glenfield Hospital, Leicester LE5 4PW, UK.
Publikováno v:
Bioinformatics (Oxford, England) [Bioinformatics] 2023 Apr 03; Vol. 39 (4).
Autor:
Shrine N; Department of Population Health Sciences, University of Leicester, Leicester, UK. nick.shrine@leicester.ac.uk., Izquierdo AG; Department of Population Health Sciences, University of Leicester, Leicester, UK., Chen J; Department of Population Health Sciences, University of Leicester, Leicester, UK., Packer R; Department of Population Health Sciences, University of Leicester, Leicester, UK., Hall RJ; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Guyatt AL; Department of Population Health Sciences, University of Leicester, Leicester, UK., Batini C; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Thompson RJ; Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Pavuluri C; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Malik V; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Hobbs BD; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Moll M; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Kim W; Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Tal-Singer R; COPD Foundation, Washington DC, USA., Bakke P; Department of Clinical Science, Unversity of Bergen, Bergen, Norway., Fawcett KA; Department of Population Health Sciences, University of Leicester, Leicester, UK., John C; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester National Institute for Health and Care Research, Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Coley K; Department of Population Health Sciences, University of Leicester, Leicester, UK., Piga NN; Department of Population Health Sciences, University of Leicester, Leicester, UK., Pozarickij A; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Millwood IY; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Li L; Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China., Wijnant SRA; Department of Respiratory Diseases, Ghent Universital Hospital, Ghent, Belgium.; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.; Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands., Lahousse L; Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.; Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands., Brusselle G; Department of Respiratory Diseases, Ghent Universital Hospital, Ghent, Belgium.; Department of Epidemiology, Eramus Medical Center, Rotterdam, The Netherlands., Uitterlinden AG; Department of Internal Medicine, Eramus Medical Center, Rotterdam, The Netherlands., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Oelsner EC; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Barr RG; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Wielscher M; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Imboden M; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Department of Public Health, University of Basel, Basel, Switzerland., Jeong A; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; Department of Public Health, University of Basel, Basel, Switzerland., Bartz TM; Cardiovascular Health Research Unit, Departments of Medicine and Biostatistics, University of Washington, Seattle, WA, USA., Gharib SA; Computational Medicine Core, Center for Lung Biology, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA., Flexeder C; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Karrasch S; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Germany.; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Gieger C; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Peters A; Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute for Medical Information Processing, Biometry and Epidemiology, Medical Faculty, Ludwig Maximilian University, Munich, Germany., Stubbe B; Department of Internal Medicine B-Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Hu X; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Ortega VE; Division of Respiratory Medicine, Department of Internal Medicine, Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ, USA., Meyers DA; Department of Medicine, University of Arizona, Tucson, AZ, USA., Bleecker ER; Department of Medicine, University of Arizona, Tucson, AZ, USA., Gabriel SB; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gupta N; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Smith AV; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Zhao JH; Department of Public and Primary Care, Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Hansen AF; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Trondheim, Norway., Langhammer A; HUNT Research Centre, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Levanger, Norway.; Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway., Willer C; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Bhatta L; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology, Trondheim, Norway., Porteous D; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Sofer T; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Lee J; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Daviglus ML; Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA., Yu B; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Lim E; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Xu H; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., O'Connor GT; Pulmonary Center, School of Medicine, Boston University, Boston, MA, USA., Thareja G; Bioinformatics Core, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar., Albagha OME; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.; Center for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Suhre K; Bioinformatics Core, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar.; Department of Biophysics and Physiology, Weill Cornell Medicine, New York, NY, USA., Granell R; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Faquih TO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Hiemstra PS; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Slats AM; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Mullin BH; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia., Hui J; Busselton Population Medical Research Institute, QEII Medical Centre, Nedlands, Western Australia, Australia.; School of Population and Global Health, University of Western Australia, Crawley, Western Australia, Australia.; 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Publikováno v:
Nature genetics [Nat Genet] 2023 Mar; Vol. 55 (3), pp. 410-422. Date of Electronic Publication: 2023 Mar 13.
Autor:
Bryant L; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Free RC; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Woolf K; University College London Medical School, London, UK., Melbourne C; Genetic Epidemiology Research Group, Department of Health Sciences, University of Leicester, Leicester, UK., Guyatt AL; Genetic Epidemiology Research Group, Department of Health Sciences, University of Leicester, Leicester, UK., John C; Genetic Epidemiology Research Group, Department of Health Sciences, University of Leicester, Leicester, UK., Gupta A; Oxford Teaching Hospitals NHS Foundation Trust, Oxford, UK., Gray LJ; Biostatistics research group, Department of Health Sciences, University of Leicester, Leicester, UK., Nellums L; Population and Lifespan Sciences, School of Medicine, University of Nottingham, Nottingham, UK., Martin CA; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK., McManus IC; University College London Medical School, London, UK., Garwood C; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Modhawdia V; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Carr S; General Medical Council, London, UK.; Department of Nephrology, University Hospitals of Leicester NHS Trust, Leicester, UK., Wain LV; Genetic Epidemiology Research Group, Department of Health Sciences, University of Leicester, Leicester, UK., Tobin MD; Genetic Epidemiology Research Group, Department of Health Sciences, University of Leicester, Leicester, UK., Khunti K; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Akubakar I; Faculty of Pop Health Sciences, School of Life & Medical Sciences, University College London, London, UK., Pareek M; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK.
Publikováno v:
International journal of epidemiology [Int J Epidemiol] 2023 Feb 08; Vol. 52 (1), pp. e38-e45.