Zobrazeno 1 - 10
of 2 979
pro vyhledávání: '"AKT-mTOR"'
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 10255-10272 (2024)
Na Guo,1,* Yu Xia,1,* Nannan He,1 Huixin Cheng,1 Lei Zhang,2 Jian Liu1,2 1The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu Province, People’s Republic of China; 2Gansu Provincial Maternity and Child-Care Hospital (G
Externí odkaz:
https://doaj.org/article/722842ef32bb4e67ac26948f00f8ecfb
Autor:
Chaoqun Wang, Yuntao Li, Yonggang Zhang, Daniel Smerin, Lijuan Gu, Shuting Jiang, Xiaoxing Xiong
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-19 (2024)
Abstract Background Triolein, a symmetric triglyceride exhibiting anti-inflammatory and antioxidant properties, has demonstrated potential in mitigating cellular damage. However, its therapeutic efficacy in ischemic stroke (IS) and underlying molecul
Externí odkaz:
https://doaj.org/article/2322faf789114aa99d5686c5ecf48b6b
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The pathogenesis of pulmonary arterial hypertension (PAH) is closely linked to the abnormal proliferation of pulmonary artery smooth muscle cells. Studies have demonstrated that microRNAs play pivotal roles in the progression of pulmonary hy
Externí odkaz:
https://doaj.org/article/e035c6fa01e8448daf7af4ae541303c3
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background The role of the RING finger protein superfamily in carcinogenesis has been widely studied, but one member of this family, RNF19A, has not yet been thoroughly explored in bladder cancer (BCa). Methods The expression levels of RNF19
Externí odkaz:
https://doaj.org/article/959fa4293ce94efc86b0db9f031d4ae3
Autor:
Zhiwei Xue, Junzhi Liu, Wenchen Xing, Feiyu Mu, Yanzhao Wu, Jiangli Zhao, Xuchen Liu, Donghai Wang, Jian Wang, Xingang Li, Jiwei Wang, Bin Huang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Exosomes (EXO) play crucial roles in intercellular communication and glioma microenvironment modulation. Tumor-associated macrophages are more likely to become M2-like type macrophages in the immunosuppressive microenvironment. He
Externí odkaz:
https://doaj.org/article/ab6eb2da5fc549e4b4af71c30d6b0f94
Autor:
Yongliang Sha, Huijie Zhuang, Jin Shi, Song Ge, Shiqing He, Yiqiu Wang, Li Ma, Hao Guo, Hui Cheng
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background β-1,3-Galactosyltransferase-4 (B3GALT4), a member of the β-1,3-galactosyltransferase gene family, is essential to the development of many malignancies. However, its biological function in breast cancer is still unknown. Method P
Externí odkaz:
https://doaj.org/article/671ae44fdb66486682acf07209fe6780
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Small cell lung cancer (SCLC) is a very aggressive tumor. Abnormal expression of BUB1 has been reported in several cancer types, wherein it plays a range of functional roles. This work aimed to elucidate the functional significance and molec
Externí odkaz:
https://doaj.org/article/9801f8bbf6704a1db5861d55a601133e
Publikováno v:
Journal of Bone Oncology, Vol 49, Iss , Pp 100652- (2024)
Background: Osteosarcoma (OS) is a highly malignant primary bone tumor primarily affecting children and adolescents. Despite advancements in therapeutic strategies, long-term survival rates for OS remain unfavorable, especially in advanced or recurre
Externí odkaz:
https://doaj.org/article/a98c351b8e1e4774bb338692068892b6
Autor:
Kaiwen Zhang, Xingyu Zheng, Yiqing Sun, Xinyu Feng, Xirong Wu, Wenlu Liu, Chao Gao, Ye Yan, Wenyan Tian, Yingmei Wang
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Ovarian cancer (OC) is a form of gynecological malignancy that is associated with worse patient outcomes than any other cancer of the female reproductive tract. Topoisomerase II α (TOP2A) is commonly regarded as an oncogene that is associated with m
Externí odkaz:
https://doaj.org/article/f828b2d674374b2d8660d30302855606
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e40117- (2024)
Background: Pancreatic cancer patients have limited treatment options and extremely poor prognosis. Dysregulations of proteasome 26S subunit, non-ATPases (PSMDs) contribute to the development of various cancers, whereas the significance of PSMDs in p
Externí odkaz:
https://doaj.org/article/95d2728ef0974407bc232837e69c4a3c