Zobrazeno 1 - 10
of 3 470
pro vyhledávání: '"AKT signaling"'
Autor:
Ruomeng Hu, Ying Wang, Wenwen Li, Hongjiang Liu, Rong Wu, Xuan Xu, Xiaohua Jiang, Qiong Xing, Jianye Wang, Zhaolian Wei
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 279-289 (2024)
Introduction: Cell transplantation is an emerging and effective therapeutic approach for enhancing uterine adhesions caused by endometrial damage. Currently, human umbilical cord blood mononuclear cells (HUCBMCs) have been extensively for tissue and
Externí odkaz:
https://doaj.org/article/0ebdf4d8c53a40089222942036367f05
Autor:
Fatmah R. Alsereidi, Zenith Khashim, Hezlin Marzook, Ahmed M. Al-Rawi, Tiana Salomon, Mahra K. Almansoori, Moustafa M. Madkour, Ahmed Mohamed Hamam, Mahmoud M. Ramadan, Quinn P. Peterson, Mohamed A. Saleh
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-22 (2024)
Abstract Abstract Dapagliflozin (DAPA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, is well-recognized for its therapeutic benefits in type 2 diabetes (T2D) and cardiovascular diseases. In this comprehensive in vitro study, we investigated DA
Externí odkaz:
https://doaj.org/article/66efeddb86da4093bfbe280b78a341bb
Autor:
Ruxue Liu, Minghan Qiu, Xinxin Deng, Meng Zhang, Zhanhua Gao, Yayun Wang, Hanwei Mei, Mengting Zhai, Qiaonan Zhang, Jie Hao, Zhen Yang, Huaqing Wang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Pancreatic cancer is a malignant tumor of the digestive tract with a high mortality rate. Erianin has antitumor activity, but the regulatory targets and mechanism of action in pancreatic cancer are unclear. The objective of this s
Externí odkaz:
https://doaj.org/article/2979d4c7c6f34c0b9f3802ea74f7a103
Autor:
Julia Delenko, Xiangying Xue, Prodyot K Chatterjee, Nathaniel Hyman, Andrew J Shih, Robert P Adelson, Polona Safaric Tepes, Peter K Gregersen, Christine N Metz
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Patients with endometriosis suffer with chronic pelvic pain and infertility, and from the lack of pharmacologic therapies that consistently halt disease progression. Differences in the endometrium of patients with endometriosis vs
Externí odkaz:
https://doaj.org/article/58b4eb40154b4c599df8834f46e7764f
Autor:
Dantong Sun, Lipin Tan, Yongbing Chen, Qiang Yuan, Kanqiu Jiang, Yangyang Liu, Yuhang Xue, Jinzhi Zhang, Xianbao Cao, Minzhao Xu, Yang Luo, Zhonghua Xu, Zhonghen Xu, Weihua Xu, Mingjing Shen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background Lung cancer remains one of the most prevalent cancer types worldwide, with a high mortality rate. Upregulation of programmed cell death protein 1 (PD-1) and its ligand (PD-L1) may represent a key mechanism for evading immune surve
Externí odkaz:
https://doaj.org/article/a5c8c51ef27847c69ee69bbe67c23fcd
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Increasing evidence has shown that many environmental and toxic factors can cause testicular damage, leading to testicular ferroptosis and subsequent male reproductive disorders. Melatonin is a major hormone and plays an vital role in regula
Externí odkaz:
https://doaj.org/article/ba225db2788345a1a2dcb170662e82b6
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 57, Iss , Pp 101045- (2024)
PSMA expression gradually increases from benign prostatic hyperplasia to adenocarcinoma of the prostate and is therefore used for the development of improved diagnostic (PSMA)‐based prostate cancer imaging tools. Pharmacological induction of PSMA i
Externí odkaz:
https://doaj.org/article/8478a7f4e35142058873a3693c25cd98
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionBladder cancer (BCa) is a common malignancy in the urinary tract. It has high recurrence rates and often requires microscopic examination, which presents significant challenges in clinical treatment. Previous research has shown that circu
Externí odkaz:
https://doaj.org/article/e52beea7415c495099a2cdced5b831b6
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 775-782 (2024)
Understanding the precise mechanism of BMSC (bone marrow mesenchymal stem cell) osteogenesis is critical for metabolic bone diseases and bone reconstruction. The histone-lysine N-methyltransferase 2D (KMT2D) acts as an important methyltransferase rel
Externí odkaz:
https://doaj.org/article/9eb636875c48482ead6ca11bec1aae6a
Autor:
Fatemeh Khaloozadeh, Ehsan Razmara, Fatemeh Asgharpour-Babayian, Alireza Fallah, Reihaneh Ramezani, Fatemeh Rouhollah, Sadegh Babashah
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 23, Pp 634-654 (2024)
Given that tumor cells primarily instigate systemic changes through exosome secretion, our study delved into the role of colorectal cancer (CRC)-secreted exosomal miR-224 in stromal reprogramming and its impact on endothelial cell angiogenesis. Furth
Externí odkaz:
https://doaj.org/article/bb600d1b8a90421b8d86cde25be43eaf