Zobrazeno 1 - 10
of 166
pro vyhledávání: '"AKT/GSK3β"'
Autor:
Haihui Xing, Guohua Chen, Faisal Raza, Hajra Zafar, Lei Xing, Qiaoyun Li, Ran Li, Shanshan Xu, Dan Chen
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 3, p 109 (2024)
Background: Severe neurological condition like Alzheimer’s disease (AD) has a significantly negative impact on families and society, wherein there is no proven cure. As one of the principal active constituents of Achyranthes bidentata Blume, ecdyst
Externí odkaz:
https://doaj.org/article/fcee73f351464c23aa3dc2686070af10
Akademický článek
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Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Optimal mitochondrial functioning is indispensable for acquiring oocyte competence and meiotic maturation, whilst mitochondrial dysfunction may lead to diminished reproductive potential and impaired fertility. The role of the intra-ovarian IGF system
Externí odkaz:
https://doaj.org/article/2850d4d03e0545ddaf9df400742d1b36
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Publikováno v:
Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Granulosa cells (GCs) in cumulus oophorus highly express follicle stimulating hormone receptor (FSHR), which is the most important mediator of both estradiol synthesis and oocyte maturation. Obese women have elevated free fatty ac
Externí odkaz:
https://doaj.org/article/0f6c9630e7e3487f937c54f05d66f04f
Autor:
Dingyi Yu, Pengli Zhang, Junying Li, Ting Liu, Yaodan Zhang, Qingqing Wang, Jianbing Zhang, Xiaoyan Lu, Xiaohui Fan
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 11, Iss 2, Pp 220-231 (2021)
Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world; however, it lacks effective and safe treatments. Ginkgo biloba dropping pill (GBDP), a unique Chinese G. biloba leaf extract preparation, exhibits antioxidan
Externí odkaz:
https://doaj.org/article/b59b2fb26b354e8a855fde0c57780457
Autor:
Xiao Lin, Fang Xu, Ke-Wen Zhang, Wu-Xia Qiu, Hui Zhang, Qiang Hao, Meng Li, Xiao-Ni Deng, Ye Tian, Zhi-Hao Chen, Ai-Rong Qian
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Osteoporosis, characterized by the destruction of bone resorption and bone formation, is a serious disease that endangers human health. Osteoporosis prevention and treatment has become one of the important research contents in the field of medicine.
Externí odkaz:
https://doaj.org/article/375a85a7c17b40daaedf7d16d61a0cb5
Publikováno v:
Di-san junyi daxue xuebao, Vol 42, Iss 12, Pp 1201-1208 (2020)
Objective To investigate how insulin affects the metabolism of amyloid precursor protein (APP) in a cell model of Alzheimer's disease (AD). Methods Human neuroblastoma SH-SY5Y cells and the nonneural cell lines HEK293 and 2EB2 were treated with diffe
Externí odkaz:
https://doaj.org/article/efbe3a3e7b9546c881c2ab80dc875f9f
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
5-Fluorouracil (5-Fu) is one of the basic drugs in colorectal cancer (CRC) chemotherapy, and its efficacy is mainly limited by the acquisition of drug resistance. However, the underlying mechanisms remain unclear. In this study, hypoxia inducible fac
Externí odkaz:
https://doaj.org/article/3ca44f3286b24504b0b94ae5ae5f43d2
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Modified Sijunzi Decoction (MSJZD) is an empirical prescription of Traditional Chinese Medicine (TCM) and has been corroborated to be effective in multiple human diseases, but its role in non-small cell lung cancer (NSCLC) is enigmatic. Here we mainl
Externí odkaz:
https://doaj.org/article/49f0a2023c24431885fafdd9cf327d6e