Zobrazeno 1 - 2
of 2
pro vyhledávání: '"AKO, adipose triglyceride lipase knockout"'
Autor:
Mussbacher, Marion, Stessel, Heike, Wölkart, Gerald, Haemmerle, Guenter, Zechner, Rudolf, Mayer, Bernd, Schrammel, Astrid
Publikováno v:
Journal of Molecular and Cellular Cardiology
Systemic deletion of the gene encoding for adipose triglyceride lipase (ATGL) in mice leads to severe cardiac dysfunction due to massive accumulation of neutral lipids in cardiomyocytes. Recently, impaired peroxisome proliferator-activated receptor
Autor:
Schrammel, Astrid, Mussbacher, Marion, Wölkart, Gerald, Stessel, Heike, Pail, Karoline, Winkler, Sarah, Schweiger, Martina, Haemmerle, Guenter, Al Zoughbi, Wael, Höfler, Gerald, Lametschwandtner, Alois, Zechner, Rudolf, Mayer, Bernd
Publikováno v:
Biochimica et Biophysica Acta
Systemic knockout of adipose triglyceride lipase (ATGL), the pivotal enzyme of triglyceride lipolysis, results in a murine phenotype that is characterized by progredient cardiac steatosis and severe heart failure. Since cardiac and vascular dysfuncti