Zobrazeno 1 - 10
of 17
pro vyhledávání: '"AKM Ghulam Muhammad"'
Autor:
Marianela Candolfi, Gwendalyn D. King, Kader Yagiz, James F. Curtin, Yohei Mineharu, AKM Ghulam Muhammad, David Foulad, Kurt M. Kroeger, Nick Barnett, Regis Josien, Pedro R. Lowenstein, Maria G. Castro
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 757-770 (2012)
Adenovirus-mediated delivery of the immune-stimulatory cytokine Flt3L and the conditionally cytotoxic thymidine kinase (TK) induces tumor regression and long-term survival in preclinical glioma (glioblastoma multiforme [GBM]) models. Flt3L induces ex
Externí odkaz:
https://doaj.org/article/48055997b2cf415fbca0be0e9b4482d5
Autor:
Maria G. Castro, Yohei Mineharu, Kader Yagiz, Pedro R. Lowenstein, Akm Ghulam Muhammad, Kurt M. Kroeger, Nick Barnett, Régis Josien, Gwendalyn D. King, Marianela Candolfi, David Foulad, James F. Curtin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 757-770 (2012)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Adenovirus-mediated delivery of the immune-stimulatory cytokine Flt3L and the conditionally cytotoxic thymidine kinase (TK) induces tumor regression and long-term survival in preclinical glioma (glioblastoma multiforme [GBM]) models. Flt3L induces ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9242b65c8691e2281958aa8b5c79449d
http://www.sciencedirect.com/science/article/pii/S1476558612800091
http://www.sciencedirect.com/science/article/pii/S1476558612800091
Autor:
Kyle R. Kelson, Chunyan Liu, Nicholas S. R. Sanderson, Kurt M. Kroeger, Maria G. Castro, Daniel Larocque, Weidong Xiong, Pedro R. Lowenstein, Akm Ghulam Muhammad, Gwendalyn D. King
Publikováno v:
Molecular Therapy. 19(10):1793-1801
Glioblastoma multiforme (GBM) is a primary brain tumor with a median survival of 14.6 months postdiagnosis. The infiltrative nature of GBM prevents complete resection and residual brain tumor cells give rise to recurrent GBM, a hallmark of this disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab4d1680b4510323ef441cc5a273f77
Autor:
Kurt M. Kroeger, Maria G. Castro, Gwendalyn D. King, Pedro R. Lowenstein, Akm Ghulam Muhammad, Serguei Bannykh, Yohei Mineharu, Chunyan Liu
Publikováno v:
Clinical Cancer Research. 17:4705-4718
Purpose: Glioblastoma multiforme (GBM) is a deadly primary brain tumor. Clinical trials for GBM using dendritic cell (DC) vaccination resulted in antitumor immune responses. Herein, we tested the hypothesis that combining in situ (intratumoral) Ad-Fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5bd290ccaca22929ddb7f3ec77d15d
https://doi.org/10.1158/1078-0432.ccr-11-0915
https://doi.org/10.1158/1078-0432.ccr-11-0915
Autor:
Charlene M. Manalo, Kurt M. Kroeger, Chunyan Liu, Maria G. Castro, Pedro R. Lowenstein, Catherine Bresee, Akm Ghulam Muhammad, Robert N. Pechnick, Gwendalyn D. King, Marianela Candolfi
Publikováno v:
Molecular Therapy. 16:682-690
Glioblastoma multiforme (GBM) is an invasive and aggressive primary brain tumor which is associated with a dismal prognosis. We have earlier developed a macroscopic, intracranial, syngeneic GBM model, in which treatment with adenoviral vectors (Ads)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b89897a1105e0372d5956a7561725b
https://doi.org/10.1038/mt.2008.18
https://doi.org/10.1038/mt.2008.18
Autor:
Marianela Candolfi, Hikmat Assi, Pedro R. Lowenstein, Akm Ghulam Muhammad, Gislaine Martins, Maria G. Castro, Kurt M. Kroeger, Nicholas R. Sanderson, Mariana Puntel, Kader Yagiz, Sofia Salehi, Naomi Keech, Robert Dunn, David Foulad, Mia Wibowo, Gabrielle E. Alzadeh, Chunyan Liu, James F. Curtin
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 10, Pp 947-960 (2011)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 10, Pp 947-960 (2011)
We have demonstrated that modifying the tumor microenvironment through intratumoral administration of adenoviral vectors (Ad) encoding the conditional cytotoxic molecule, i.e., HSV1-TK and the immune-stimulatory cytokine, i.e., fms-like tyrosine kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf0aa42ffb45631fabe5f8b1b6f397a
http://www.sciencedirect.com/science/article/pii/S1476558611800825
http://www.sciencedirect.com/science/article/pii/S1476558611800825
Autor:
Hikmat Assi, Maria G. Castro, Yohei Mineharu, Mariana Puntel, Kurt M. Kroeger, Weidong Xiong, Mia Wibowo, Pedro R. Lowenstein, David Foulad, Akm Ghulam Muhammad, Kader Yagiz, Gregory J. Baker, Chunyan Liu, Marianela Candolfi
Publikováno v:
Anti-cancer agents in medicinal chemistry. 11(8)
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. GBM is very aggressive due to its poor cellular differentiation and invasiveness, which makes complete surgical resection virtually impossible. Therefore, GBM's invasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b044859da0f1258edec4863c22a6ef
https://pubmed.ncbi.nlm.nih.gov/21707497
https://pubmed.ncbi.nlm.nih.gov/21707497
Autor:
Chunyan Liu, Sharon Lee, Kurt M. Kroeger, Ali Zadmehr, Gabrielle E. Ahlzadeh, Marianela Candolfi, Ronald Rodriguez, Clive N. Svendsen, Waldemar Debinski, Kader Yagiz, Mariana Puntel, Pedro R. Lowenstein, Akm Ghulam Muhammad, Maria G. Castro, David Foulad, Dhruv Sareen, Matthew Tesarfreund, Weidong Xiong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(46)
Restricting the cytotoxicity of anticancer agents by targeting receptors exclusively expressed on tumor cells is critical when treating infiltrative brain tumors such as glioblastoma multiforme (GBM). GBMs express an IL-13 receptor (IL13Rα2) that di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e177aaa001d6c22291aa0ed0fae0c4
https://pubmed.ncbi.nlm.nih.gov/21030678
https://pubmed.ncbi.nlm.nih.gov/21030678
Autor:
David Foulad, Weidong Xiong, Gregory J. Baker, Kurt M. Kroeger, Maria G. Castro, Chunyan Liu, Philip Ng, James F. Curtin, Alireza Salem, Donna Palmer, Pedro R. Lowenstein, Niyati Bondale, Akm Ghulam Muhammad, Jonathan Lerner, Mariana Puntel, Kader Yagiz, Marianela Candolfi, Catherine Farrokhi, Robert N. Pechnick, Katherine E. Lawrence
Publikováno v:
Articles
Glioblastoma multiforme (GBM) is the most common and most aggressive primary brain tumor in humans. Systemic immunity against gene therapy vectors has been shown to hamper therapeutic efficacy; however, helper-dependent high-capacity adenovirus (HC-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdc53f3bef89146879fc1d267103d89
https://arrow.tudublin.ie/context/scschbioart/article/1053/viewcontent/Muhammad_AKM_Clin_Pharmacol_Ther_2010_for_Arrow.pdf
https://arrow.tudublin.ie/context/scschbioart/article/1053/viewcontent/Muhammad_AKM_Clin_Pharmacol_Ther_2010_for_Arrow.pdf
Autor:
Robert N. Pechnick, Alireza Salem, Jonathan Lerner, Niyati Bondale, Kurt M. Kroeger, Chunyan Liu, Philip Ng, Mariana Puntel, Maria G. Castro, Marianela Candolfi, James F. Curtin, Weidong Xiong, Catherine Farrokhi, Donna Palmer, Kader Yagiz, Pedro R. Lowenstein, Akm Ghulam Muhammad
Publikováno v:
Journal of virology. 84(12)
Glioblastoma multiforme (GBM) is a deadly primary brain tumor. Conditional cytotoxic/immune-stimulatory gene therapy (Ad-TK and Ad-Flt3L) elicits tumor regression and immunological memory in rodent GBM models. Since the majority of patients enrolled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eec9c311b653a5e3d9f8df61d81f313
https://pubmed.ncbi.nlm.nih.gov/20375153
https://pubmed.ncbi.nlm.nih.gov/20375153