Zobrazeno 1 - 7
of 7
pro vyhledávání: '"AKIYOSHI SUGANUMA"'
Autor:
Shigeki Sawada, Yuji Hori, Akiyoshi Suganuma, Kazuo Tsukidate, Kanako Uchida, Toyohiko Aoki, Atsushi Hakura
Publikováno v:
Genes and Environment. 32:53-60
The effect of dimethyl sulfoxide (DMSO) on the mutagenicity of 14 promutagens belonging to several chemical classes and one direct mutagen as a reference compound was examined in the Ames preincubation test, to clarify how much the test results were
Autor:
Shigeki Sawada, Toyohiko Aoki, Kanako Uchida, Atsushi Hakura, Yuji Hori, Akiyoshi Suganuma, Kazuo Tsukidate, Tadakazu Sugihara
Publikováno v:
Genes and Environment. 32:1-6
Dimethyl sulfoxide (DMSO) is generally believed to be non-cytotoxic at the concentrations used in the routine Ames test. In the present study, we found that DMSO reduced the number of bacterial survivors at a concentration of 14% in the treatment mix
Autor:
Kenji Ishihara, Akira Inomata, Akiyoshi Suganuma, Toyohiko Aoki, Kohei Sawada, Tsuyoshi Yokoi, Yuji Uemura, Naoki Asai, Naruo Katsutani
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 105:156-166
This (1)H nuclear magnetic resonance metabonomics study was aimed to determine urinary biomarkers of cholestasis resulting from inhibition of biliary secretion of bile or obstruction of bile flow. To inhibit biliary secretion of bile, cyclosporine A
Autor:
Yoshiro Yamaura, Akiyoshi Suganuma, Satoshi Suzuki, Yasuhiro Fujikawa, Shinobu Yui, Yasuko Niikura, Tetsuo Satoh
Publikováno v:
Human & Experimental Toxicology. 24:333-336
Egasyn-βglucuronidase complex is located at the luminal site of liver microsomal endoplasmic reticulum. When organophosphorus insecticides (OP) are incorporated into the liver microsomes, they become tightly bound to egasyn, a carboxylesterase isozy
Autor:
Kohei Sawada, Taisuke Uehara, Toyohiko Aoki, Akiyoshi Suganuma, Kazuo Tsukidate, Motohiro Shiotani, Dai Kakiuchi, Kyoko Nakano-Ito
Publikováno v:
Molecular medicine reports. 11(2)
Vitamin A deficiency (VAD) caused by malnutrition and certain intestinal diseases induces visual impairments, including night blindness and photoreceptor cell dysfunction as indicated by reduced a‑ and b‑waves in an electroretinogram (ERG). The e
Autor:
Akiyoshi Suganuma, Kazuo Tsukidate, Yuki Seki, Jiro Sonoda, Kerns William D, Atsushi Hakura, Toyohiko Aoki, Satoru Hosokawa
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 49(11)
Previously, we reported that the mutation frequency was markedly increased in the colon after the oral treatment of mice with an environmental mutagen/carcinogen, benzo[ a ]pyrene (BP); however this was not followed by tumor development. The reasons
Autor:
DAI KAKIUCHI, TAISUKE UEHARA, MOTOHIRO SHIOTANI, KYOKO NAKANO-ITO, AKIYOSHI SUGANUMA, TOYOHIKO AOKI, KAZUO TSUKIDATE, KOHEI SAWADA
Publikováno v:
Molecular Medicine Reports; 2015, Vol. 11 Issue 2, p995-1003, 9p