Zobrazeno 1 - 10
of 274
pro vyhledávání: '"AKIHIRO SAKAI"'
Autor:
Takashi Matsuki, Daisuke Kawakita, Hideaki Takahashi, Takuro Okada, Akihiro Sakai, Yushi Ueki, Hiroshi Tsuge, Kenji Hanyu, Kaho Momiyama, Ryusuke Shodo, Mayu Yamauchi, Yukiko Asako, Hideaki Hirai, Toshitaka Nagao, Yuichiro Tada
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Although immune checkpoint inhibitors (ICIs) are effective in some patients with salivary gland carcinoma (SGC), biomarkers which predict the efficacy and prognosis of SGC patients treated with pembrolizumab have not been identified. We cond
Externí odkaz:
https://doaj.org/article/b5b7acb4c83f4a13bea2ec729ee7a8c0
Autor:
Hiroaki Iijima, Akihiro Sakai, Koji Ebisumoto, Go Ogura, Mayu Yamauchi, Takanobu Teramura, Aritomo Yamazaki, Takane Watanabe, Toshihide Inagi, Ryoko Yanagiya, Ai Yamamoto, Hiroshi Ashida, Yoshiyuki Ota, Yurina Sato, Naoya Kobayashi, Daisuke Maki, Naoya Nakamura, Kenji Okami
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 18 (2024)
Background: Recurrent or metastatic squamous cell carcinoma of the head and neck (R/MHNSCC) is a challenging malignancy with a poor prognosis and limited treatment options. Nivolumab, an immune checkpoint inhibitor (ICI) targeting the programmed cell
Externí odkaz:
https://doaj.org/article/f9e11e18f88743a487e81bbe064a545b
Autor:
Chihiro Fushimi, Hideaki Takahashi, Daisuke Kawakita, Satoshi Kano, Kiyoaki Tsukahara, Hiroyuki Ozawa, Kenji Okami, Akihiro Sakai, Keisuke Yamazaki, Takuro Okada, Toyoyuki Hanazawa, Yuichiro Sato, Yorihisa Imanishi, Akira Shimizu, Takashi Matsuki, Toshitaka Nagao, Yuichiro Tada
Publikováno v:
Cancer Medicine, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Background Salivary duct carcinoma (SDC) is a high‐grade adenocarcinoma with a 5‐year survival rate of 40%. Although drug therapy has improved patients' prognosis, the impact of brain metastasis (BM) remains poorly understood. We aimed t
Externí odkaz:
https://doaj.org/article/15d1e28de5a0440e94de49f5d8890cef
Autor:
Hiroaki Iijima, Akihiro Sakai, Koji Ebisumoto, Mayu Yamauchi, Takanobu Teramura, Aritomo Yamazaki, Toshihide Inagi, Kenji Okami
Publikováno v:
Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-6 (2023)
Abstract Background Immune checkpoint inhibitors might cause immune-related adverse events that are still largely unknown. Case presentation An 80-year-old Asian female was diagnosed with cervical lymph node metastasis from lip cancer (cT1N0M0) and u
Externí odkaz:
https://doaj.org/article/e6a57d272a5f48668b1afc70a28dc3b9
Autor:
Akihiro Sakai, Koji Ebisumoto, Hiroaki Iijima, Mayu Yamauchi, Takanobu Teramura, Aritomo Yamazaki, Takane Watanabe, Toshihide Inagi, Daisuke Maki, Kenji Okami
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Objective This study aimed to evaluate the clinical effectiveness of chemotherapy following immune checkpoint inhibitors (ICI). The association between inflammatory and nutritional factors and prognosis has also been investigated. Methods We
Externí odkaz:
https://doaj.org/article/ab17ca163ec044e7ad86ac08125c606d
Autor:
Akihiro Sakai, Koji Ebisumoto, Hiroaki Iijima, Mayu Yamauchi, Takanobu Teramura, Aritomo Yamazaki, Takane Watanabe, Toshihide Inagi, Daisuke Maki, Kenji Okami
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 8, Iss 3, Pp 667-674 (2023)
Abstract Background Transoral salvage surgery has the potential to preserve a patient's quality of life. Therefore, we investigated the outcomes, safety, and risk factors for postoperative complications of salvage transoral videolaryngoscopic surgery
Externí odkaz:
https://doaj.org/article/0a972d5c068a45008f197accff2b520a
Autor:
Akihiro Sakai, Koji Ebisumoto, Hiroaki Iijima, Mayu Yamauchi, Daisuke Maki, Tsuyoshi Fukuzawa, Kenji Okami
Publikováno v:
Cancer Reports, Vol 7, Iss 2, Pp n/a-n/a (2024)
Abstract Background The abscopal effect is a rare phenomenon in which localized radiation therapy triggers tumor reduction in nontargeted areas. Although this phenomenon has been observed in various cancer types, it remains infrequent and not fully u
Externí odkaz:
https://doaj.org/article/51ff6ff41fc8427fb3a226a054e79318
Autor:
Shinji Kohsaka, Yuichiro Tada, Mizuo Ando, Masato Nakaguro, Yukina Shirai, Toshihide Ueno, Shinya Kojima, Hideaki Hirai, Natsuki Saigusa, Satoshi Kano, Kiyoaki Tsukahara, Takafumi Togashi, Hiroyuki Ozawa, Takahito Kondo, Kenji Okami, Hideaki Takahashi, Daisuke Kawakita, Chihiro Fushimi, Takayoshi Suzuki, Akira Shimizu, Isaku Okamoto, Takuro Okada, Yuichiro Sato, Yorihisa Imanishi, Yoshihiro Watanabe, Akihiro Sakai, Koji Ebisumoto, Yukiko Sato, Makoto Urano, Yoshitaka Honma, Keisuke Yamazaki, Yushi Ueki, Toyoyuki Hanazawa, Yuki Saito, Tomotaka Shimura, Toshitaka Nagao, Hiroyuki Mano
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-12 (2022)
Abstract Molecular targets and predictive biomarkers for prognosis in salivary duct carcinoma (SDC) have not been fully identified. We conducted comprehensive molecular profiling to discover novel biomarkers for SDC. A total of 67 SDC samples were ex
Externí odkaz:
https://doaj.org/article/55457a756c094554a6dc1105eb124504
Autor:
Daichi Murakami, Takahito Kimura, Masamitsu Kono, Akihiro Sakai, Tomohiro Suenaga, Masanobu Hiraoka, Hideki Sakatani, Makiko Ohtani, Hiroyuki Suzuki, Daisuke Tokuhara, Muneki Hotomi
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Sensorineural hearing loss associated with Kawasaki disease has been increasingly reported, but its etiology remains unclear. Most reported cases of sensorineural hearing loss associated with Kawasaki disease have been mild and reversible during acut
Externí odkaz:
https://doaj.org/article/ce9dc8f7583947b58df6530c07926831
Autor:
Kyohei Yugawa, Takashi Maeda, Shigeyuki Nagata, Jin Shiraishi, Akihiro Sakai, Shohei Yamaguchi, Kozo Konishi, Kenkichi Hashimoto
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-9 (2022)
Abstract Background Posthepatectomy liver failure (PHLF) is a life-threatening complication following hepatic resection. The aspartate aminotransferase-to-platelet ratio index (APRI) is a non-invasive model for assessing the liver functional reserve
Externí odkaz:
https://doaj.org/article/63ba096badf64019bfe57a9d237992bf