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Akademický článek

Chromosomal localization of lipolytic enzymes in the mouse: pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase

Autor: CH Warden, RC Davis, MY Yoon, DY Hui, K Svenson, YR Xia, A Diep, KY He, AJ Lusis

Publikováno v: Journal of Lipid Research, Vol 34, Iss 8, Pp 1451-1455 (1993)

Several lipases and their cofactors are involved in the absorption, transport, storage, and mobilization of lipids. As part of an effort to examine the role of these enzymes in plasma lipid metabolism and genetic susceptibility to atherosclerosis, we

Externí odkaz: https://doaj.org/article/c8013e8b0fa946c282fba2bddee81c5d

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Akademický článek

Genetic variation in mouse apolipoprotein A-IV expression is determined pre- and post-transcriptionally

Autor: K Reue, DA Purcell-Huynh, TH Leete, MH Doolittle, A Durstenfeld, AJ Lusis

Publikováno v: Journal of Lipid Research, Vol 34, Iss 6, Pp 893-903 (1993)

Among inbred mouse strains there is a striking genetic variation in the levels of apolipoprotein A-IV (apoA-IV) mRNA in the liver, although intestinal mRNA levels vary only twofold in these strains. In the present study we have characterized the apoA

Externí odkaz: https://doaj.org/article/727232308c24490c982291ea275d9fa1

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Akademický článek

Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice

Autor: S Dueland, J Drisko, L Graf, D Machleder, AJ Lusis, RA Davis

Publikováno v: Journal of Lipid Research, Vol 34, Iss 6, Pp 923-931 (1993)

Compared to BALB/c mice, inbred C57BL/6 mice are more susceptible to developing fatty streak atherosclerotic lesions when fed a cholesterol-rich diet containing taurocholate. We examined the metabolic basis for the taurocholate requirement. In contra

Externí odkaz: https://doaj.org/article/44afd7d08d7e499396736095cdd3fc91

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Akademický článek

Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression.

Autor: JJ Hwa, S Zollman, CH Warden, BA Taylor, PA Edwards, AM Fogelman, AJ Lusis

Publikováno v: Journal of Lipid Research, Vol 33, Iss 5, Pp 711-725 (1992)

Inbred strains of mice exhibit large genetic variations in hepatic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity. A tissue-specific genetic variation between the strains BALB/c and C57BL/6, resulting in about 5-fold higher levels

Externí odkaz: https://doaj.org/article/880dbab9f3f041b1b4c125667912c622

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Akademický článek

Phenotypic characterization of the Ath-1 gene controlling high density lipoprotein levels and susceptibility to atherosclerosis.

Autor: RC LeBoeuf, MH Doolittle, A Montcalm, DC Martin, K Reue, AJ Lusis

Publikováno v: Journal of Lipid Research, Vol 31, Iss 1, Pp 91-101 (1990)

The Ath-1 gene determines the levels of high density lipoprotein (HDL) lipid in response to a high fat diet challenge as well as susceptibility to diet-induced atherosclerosis in mice (Paigen et al. 1987. Proc. Natl. Acad. Sci. USA. 84: 3763-3767). A

Externí odkaz: https://doaj.org/article/65bfbca461c9460b956780d7fd99dbaa

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Akademický článek

Description of two different patients with abetalipoproteinemia: synthesis of a normal-sized apolipoprotein B-48 in intestinal organ culture.

Autor: ME Bouma, I Beucler, M Pessah, C Heinzmann, AJ Lusis, HY Naim, T Ducastelle, B Leluyer, J Schmitz, R Infante

Publikováno v: Journal of Lipid Research, Vol 31, Iss 1, Pp 1-15 (1990)

We describe here two patients, M. P. and S. L., with recessive abetalipoproteinemia. Analysis of restriction fragments of DNA from both patients using cDNA probes spanning the entire apolipoprotein B gene revealed no major insertions or deletions. Fu

Externí odkaz: https://doaj.org/article/f5d663306da24691ba7ec22588cfeb3c

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Erratum: Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

Autor: J Lamb, Pek Yee Lum, L.W. Castellani, Christopher D. Armour, J. Stockton, EE Schadt, S Edwards, TA Drake, M. Mehrabian, M. Suh, H. Allayee, AJ Lusis

Publikováno v: Nature Genetics. 37:1381-1381

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1f2e9d92417f29e1f87bca0e59d1fc2
https://doi.org/10.1038/ng1205-1381a

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Human leukemia cell line K562 responds to erythroid-potentiating activity

Autor: CE Gauwerky, AJ Lusis, DW Golde

Publikováno v: Blood. 59(2)

We report that erythroid-potentiating activity (EPA), known to stimulate the proliferation of normal human erythroid precursors in vitro, has a growth-promoting effect on human K562 erythroleukemia cells and Friend mouse erythroleukemia cells. Detail

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2df06217aaf01c60f89ff1776e2998
https://pubmed.ncbi.nlm.nih.gov/6976809

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An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1)

Autor: HP Koeffler, R Billing, AJ Lusis, R Sparkes, DW Golde

Publikováno v: Blood. 56(2)

A variant subline (KG-1a) of the human acute myelogenous leukemia (AML) cell line (KG-1) has been isolated. The cells retain the same constitutive markers as the parent line, including HLA antigens, isoenzymes, and karyotype. The cells from the subli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138f1405aa3be909170fb1cd975eaa05
https://pubmed.ncbi.nlm.nih.gov/6967340

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